MEDICINAL AND BIOINORGANIC CHEMISTRY
CHE3MBC
2020
Credit points: 15
Subject outline
In this subject, the chemical principles encountered in the prerequisite subjects will be applied to issues of biological relevance within themes of medicinal chemistry, heterocyclic chemistry and bioinorganic chemistry. In the medicinal chemistry topic you will learn about issues related to pharmaceutical concerns from a chemical perspective, including an overview of the process of bringing new medicinal compounds to market. Most molecules of pharmaceutical relevance comprise organic heterocyclic rings containing nitrogen and oxygen; the synthetic strategies to access these compounds will be expanded in the heterocyclic chemistry topic with application to real-world examples. In the bioinorganic topic you will focus on the interplay of metal elements with biology from a chemical perspective # both essential metal elements such as iron and zinc, as well as the chemical basis for which toxic metal elements (e.g. mercury) act on the body, and finally how metal containing compounds can act as therapeutics. In this subject you will also gain experience conducting and interpreting laboratory experiments related to organic and bioinorganic chemistry.
School: Molecular Sciences (Pre 2022)
Credit points: 15
Subject Co-ordinator: Belinda Abbott
Available to Study Abroad/Exchange Students: Yes
Subject year level: Year Level 3 - UG
Available as Elective: No
Learning Activities: N/A
Capstone subject: No
Subject particulars
Subject rules
Prerequisites: Students must have completed CHE2FCA and CHE2FCB or Students must be admitted in the following course: SMCHS
Co-requisites: N/A
Incompatible subjects: N/A
Equivalent subjects: N/A
Quota Management Strategy: N/A
Quota-conditions or rules: N/A
Special conditions: N/A
Minimum credit point requirement: N/A
Assumed knowledge: N/A
Learning resources
Introduction to Medicinal Chemistry
Resource Type: Book
Resource Requirement: Recommended
Author: Patrick G
Year: 2013
Edition/Volume: N/A
Publisher: Oxford University Press
ISBN: N/A
Chapter/article title: N/A
Chapter/issue: N/A
URL: N/A
Other description: N/A
Source location: N/A
Organic Chemistry
Resource Type: Book
Resource Requirement: Recommended
Author: McMurry J
Year: 2016
Edition/Volume: N/A
Publisher: Thomson Brooks/Cole
ISBN: N/A
Chapter/article title: N/A
Chapter/issue: N/A
URL: N/A
Other description: N/A
Source location: N/A
Career Ready
Career-focused: No
Work-based learning: No
Self sourced or Uni sourced: N/A
Entire subject or partial subject: N/A
Total hours/days required: N/A
Location of WBL activity (region): N/A
WBL addtional requirements: N/A
Graduate capabilities & intended learning outcomes
Graduate Capabilities
Intended Learning Outcomes
Melbourne (Bundoora), 2020, Semester 2, Day
Overview
Online enrolment: Yes
Maximum enrolment size: N/A
Subject Instance Co-ordinator: Belinda Abbott
Class requirements
Laboratory ClassWeek: 32 - 43
Three 5.00 hours laboratory class per study period on weekdays during the day from week 32 to week 43 and delivered via face-to-face.
The laboratory program consists of 3 classes (5 hours each) over the semester. A schedule of experiments will be made available to students on the LMS at the start of semester.
LectureWeek: 31 - 43
Four 1.00 hour lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
SeminarWeek: 31 - 31
One 5.00 hours seminar per study period on weekdays during the day from week 31 to week 31 and delivered via face-to-face.
Laboratory safety introduction will be held in the first week of semester.
Assessments
| Assessment element | Category | Contribution | Hurdle | % | ILO* |
|---|---|---|---|---|---|
2 hr written examination (equivalent to 1500 essay words)A 1.5 hour paper scheduled for 2 hours in the central examination period. | N/A | N/A | No | 35 | SILO1 |
Tests (equivalent to 600 essay words)Two in class tests during semester. | N/A | N/A | No | 15 | SILO1 |
Essay assignment (equivalent to 450 essay words)One essay during semester for the bioinorganic chemistry component. | N/A | N/A | No | 10 | SILO4 |
Online quizzes (equivalent to 450 essay words)Two LMS quizzes during semester. | N/A | N/A | No | 10 | SILO1 |
Laboratory work, written reports (equivalent to 1500 essay words)HURDLE for subject pass, from accreditation with RACI. Students must complete a minimum 75% of lab assessment, and must obtain a score of at least 50% for the laboratory component of the subject. Develops and assess competency in practical skills, and in data handling and reporting. | N/A | N/A | Yes | 30 | SILO1, SILO2, SILO3 |