pha1pfa pharmaceutical formulation a

PHARMACEUTICAL FORMULATION A

PHA1PFA

2019

Credit points: 15

Subject outline

This subject introduces students to the pharmaceutical sciences and covers the areas of physical chemistry and laboratory skills necessary to prepare and understand the formulation of pharmaceutical products. This subject focuses on solution formulations. Students will be introduced to products and routes of administration, absorption, distribution and elimination of drugs. They will study pharmaceutically relevant physicochemical phenomena, formulation of solutions, and pharmaceutical calculations.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorDavid Morton

Available to Study Abroad StudentsNo

Subject year levelYear Level 1 - UG

Exchange StudentsNo

Subject particulars

Subject rules

Prerequisites Students enrolled in SHPB or SBPB, or SVPB must complete CHE1C1A and PHA1IPP. Students enrolled in SBMSSI or SBSSI, or SBSCB must complete CHE1C1A.

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Special conditionsN/A

Learning resources

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsAulton's Pharmaceutics The Design and Manufacture of MedicinesPrescribedAulton, ME and Taylor, K. 2018Churchill Livingstone
ReadingsAustralian Pharmaceutical Formulary and Handbook APF24PrescribedSansom, L. (ed.) 2018Pharmaceutical Society of Australia
ReadingsExtemporaneous Dispensing Record Sheet folderPrescribedLa Trobe University 2019Available from the bookshop
ReadingsPharmaceutical PracticePrescribedRees, JA Smith, I and Watson JChurchill Livingstone
ReadingsMartindale: the Complete Drug ReferenceRecommendedBrayfield, A 2017Pharmaceutical Press
ReadingsPhysical ChemistryRecommendedEngel, T and Reid, P 2013Pearson
ReadingsPharmaceutical CalculationsPrescribedAnsel, C and Stockton, SJ 2017Walters Kluwer

Graduate capabilities & intended learning outcomes

01. Apply methods of compounding by manufacturing and dispensing a simple solution product in accordance with the PSA Professional Practice Standard for Compounding.

Activities:
Product Labelling And Extemporaneous products: During tutorials and laboratories labelling and documentation for products is practiced. The labelling and documentation must meet the PSA standard, and so students are assessed on these important professional writing skills.

02. Predict and explain the properties of solutions by the calculation and interpretation of thermodynamic parameters and describe how these relate to pharmaceutical solutions.

Activities:
Discussed during pre-lab activities and tutorials. Students are required to explain orally the significance of the physical chemistry to formulation and bioavailability, and also the role of ingredients in a formulation.

03. Assess the advantages and disadvantages of a wide variety of dosage forms by describing how dosage form can impact on factors such as bioavailability, stability and product handling.

Activities:
Discussed during pre-lab activities and tutorials. Students explain orally the significance of the physical chemistry to formulation and bioavailability, and also the role of ingredients in a formulation.

04. Apply pharmacokinetic principles by describing ADME and how this can be affected by dosage form and route of administration.

Activities:
Discussed in Lectures and tutorials.

05. Accurately perform simple pharmaceutical calculations

Activities:
There is a 50 minute calculation test. Preparation is via three online LMS quizzes, to sit the calculation test the students must achieve 80% in the final LMS quiz by the test date. The questions in the final test are a selection of questions from these LMS quizzes. Students are allowed to repeat the quizzes to reach the hurdle benchmark until the end of the examination period.

Subject options

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Start date between: and    Key dates

Bendigo, 2019, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorDavid Morton

Class requirements

TutorialWeek: 31 - 43
Two 1.0 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Pre laboratory and calculation tutorials. On-line quizzes to complete."

LectureWeek: 31 - 43
Three 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Laboratory ClassWeek: 31 - 43
Ten 3.0 hours laboratory class per study period on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Assessments

Assessment elementComments%ILO*
3-hour examination6002, 05, 04, 03
Three online in-class tests, Pharmaceutical Calculations (450-words equivalent)Students undertake three online LMS quizzes with immediate feedback. They must achieve 80% on each quiz to open the next quiz, including the final quiz, to sit the in-class test.1005
Pharmaceutics practical skills test (500-words equivalent)2001, 02, 03, 04
Prelab tests and activities (200-words equivalent)Formative assessment to support learning in laboratory exercises. May include on-line tests and interviews.1001, 02, 03, 04

Singapore (PSB), 2019, Term L6, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

Laboratory ClassWeek: 44 - 48
One 15.0 hours laboratory class per study period on weekdays during the day from week 44 to week 48 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."

LectureWeek: 44 - 48
One 30.0 hours lecture per study period on weekdays during the day from week 44 to week 48 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."

TutorialWeek: 44 - 48
One 10.0 hours tutorial per study period on weekdays during the day from week 44 to week 48 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments%ILO*
3-hour examination6002, 05, 04, 03
Three online in-class tests, Pharmaceutical Calculations (450-words equivalent)Students undertake three online LMS quizzes with immediate feedback. They must achieve 80% on each quiz to open the next quiz, including the final quiz, to sit the in-class test.1005
Pharmaceutics practical skills test (500-words equivalent)2001, 02, 03, 04
Prelab tests and activities (200-words equivalent)Formative assessment to support learning in laboratory exercises. May include on-line tests and interviews.1001, 02, 03, 04

Singapore (PSB), 2019, Term L2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

Laboratory ClassWeek: 11 - 15
One 15.0 hours laboratory class per study period on weekdays during the day from week 11 to week 15 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."

LectureWeek: 11 - 15
One 30.0 hours lecture per study period on weekdays during the day from week 11 to week 15 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."

TutorialWeek: 11 - 15
One 10.0 hours tutorial per study period on weekdays during the day from week 11 to week 15 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments%ILO*
3-hour examination6002, 05, 04, 03
Three online in-class tests, Pharmaceutical Calculations (450-words equivalent)Students undertake three online LMS quizzes with immediate feedback. They must achieve 80% on each quiz to open the next quiz, including the final quiz, to sit the in-class test.1005
Pharmaceutics practical skills test (500-words equivalent)2001, 02, 03, 04
Prelab tests and activities (200-words equivalent)Formative assessment to support learning in laboratory exercises. May include on-line tests and interviews.1001, 02, 03, 04

Singapore (PSB), 2019, Term L2, Night

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

Laboratory ClassWeek: 11 - 15
One 15.0 hours laboratory class per study period on weekdays at night from week 11 to week 15 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."

LectureWeek: 11 - 15
One 30.0 hours lecture per study period on weekdays at night from week 11 to week 15 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."

TutorialWeek: 11 - 15
One 10.0 hours tutorial per study period on weekdays at night from week 11 to week 15 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments%ILO*
3-hour examination6002, 05, 04, 03
Three online in-class tests, Pharmaceutical Calculations (450-words equivalent)Students undertake three online LMS quizzes with immediate feedback. They must achieve 80% on each quiz to open the next quiz, including the final quiz, to sit the in-class test.1005
Pharmaceutics practical skills test (500-words equivalent)2001, 02, 03, 04
Prelab tests and activities (200-words equivalent)Formative assessment to support learning in laboratory exercises. May include on-line tests and interviews.1001, 02, 03, 04

Singapore (PSB), 2019, Term L6, Night

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

Laboratory ClassWeek: 44 - 48
One 15.0 hours laboratory class per study period on weekdays at night from week 44 to week 48 and delivered via face-to-face.
"15 hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."

LectureWeek: 44 - 48
One 30.0 hours lecture per study period on weekdays at night from week 44 to week 48 and delivered via face-to-face.
"30 hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online"

TutorialWeek: 44 - 48
One 10.0 hours tutorial per study period on weekdays at night from week 44 to week 48 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online"

Assessments

Assessment elementComments%ILO*
3-hour examination6002, 05, 04, 03
Three online in-class tests, Pharmaceutical Calculations (450-words equivalent)Students undertake three online LMS quizzes with immediate feedback. They must achieve 80% on each quiz to open the next quiz, including the final quiz, to sit the in-class test.1005
Pharmaceutics practical skills test (500-words equivalent)2001, 02, 03, 04
Prelab tests and activities (200-words equivalent)Formative assessment to support learning in laboratory exercises. May include on-line tests and interviews.1001, 02, 03, 04