PHARMACEUTICAL FORMULATION A

PHA1PFA

2016

Credit points: 15

Subject outline

This subject introduces students to the pharmaceutical sciences and covers the areas of physical chemistry and laboratory skills necessary to prepare and understand the formulation of pharmaceutical products. This subject focuses on solution formulations. Students will be introduced to products and routes of administration, absorption, distribution and elimination of drugs. They will study pharmaceutically relevant physicochemical phenomena, formulation of solutions, and pharmaceutical calculations.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorJoy Spark

Available to Study Abroad StudentsNo

Subject year levelYear Level 1 - UG

Exchange StudentsNo

Subject particulars

Subject rules

Prerequisites CHE1C1A

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Special conditionsN/A

Learning resources

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsAulton's Pharmaceutics The Design and Manufacture of MedicinesPrescribedAulton, ME and Taylor, K. 20134TH ED., LONDON: CHURCHILL LIVINGSTONE
ReadingsAustralian Pharmaceutical Formulary and HandbookPrescribedPharmaceutical Society of Australia22ND ED, CANBERRA: PHARMACEUTICAL SOCIETY OF AUSTRALIA, 2012
ReadingsPharmaceutical Formulations - Solutions. Practical Laboratory ManualPrescribedLa Trobe UniversityLa Trobe University
ReadingsPharmaceutical PracticePrescribedRees, JA Smith, I and Watson J5TH ED., LONDON: CHURCHILL LIVINGSTONE
ReadingsMartindale: the complete drug referenceRecommendedPharmaceutical Press35TH EDN, LONDON: PHARMACEUTICAL PRESS, 2007.
ReadingsPhysical ChemistryRecommendedEngel, T and Reid, P 2006PEARSON: SAN FRANCISCO

Graduate capabilities & intended learning outcomes

01. Apply methods of compounding by manufacturing and dispensing a solution product in accordance with the PSA Professional Practice Standard for Compounding.

Activities:
Product Labelling And Extemporaneous products: During the semester labelling and documentation for products is assessed. The labelling and documentation must meet the PSA standard, and so students are assessed on these important professional writing skills. At the end of the semester a practical test is given and students must reach the hurdle benchmark by completing the tasks in line with the PSA guidelines. Students are also assessed in the interview, where they can be asked questions on any of the practical tasks they have been given in the semester. They could be asked specifically about a product, a label, or the science of the formulation.

02. Predict and explain the properties of solutions by the calculation and interpretation of thermodynamic parameters and describe how these relate to pharmaceutical solutions.

Activities:
Assessed in the exam and during the prac interview. In addition to written calculations, students must be able to explain orally the significance of the physical chemistry to formulation and bioavailability, and also the role of ingredients in a formulation.

03. Assess the advantages and disadvantages of a wide variety of dosage forms by describing how dosage form can impact on factors such as bioavailability, stability and product handling.

Activities:
Assessed in the exam, and during the prac interview. In addition to written calculations, students must be able to explain orally the significance of the physical chemistry to formulation and bioavailability, and also the role of ingredients in a formulation.

04. Apply pharmacokinetic principles by describing ADME and how this can be affected by dosage form and route of administration.

Activities:
Assessed in the final exam and the practical interview.

05. Accurately calculate dosage by completion of calculation quizzes and hurdle test.

Activities:
There is a 50 minute calculations test that is a hurdle. Preparation is via a series of LMS quizzes. The questions in the final test are a selection of questions from these LMS quizzes. Students are allowed to repeat the test until they reach the hurdle benchmark.

Subject options

Select to view your study options…

Start date between: and    Key dates

Bendigo, 2016, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJoy Spark

Class requirements

Laboratory Class Week: 31 - 43
One 2.5 hours laboratory class per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delievered Face-to-Face or as Directed Online Learning."

Lecture Week: 31 - 43
Three 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Or Delivery Method: On-Line"

Tutorial Week: 31 - 43
One 1.0 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Or Type: On-Line Quiz Or Delivery Method: On-Line"

Assessments

Assessment elementComments% ILO*
3-hour examination60 02, 05, 04, 03
In-class test, Pharmaceutical CalculationsHurdle requirement: must produce competent documentation and labels, must also achieve 70% in calculation test.10 05
Pharmaceutics practical skills30 04, 03, 02, 01

Singapore, 2016, Week 45-51, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJoy Spark

Class requirements

Laboratory Class Week: 45 - 51
One 15.0 hours laboratory class per study period on weekdays during the day from week 45 to week 51 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."

Lecture Week: 45 - 51
One 30.0 hours lecture per study period on weekdays during the day from week 45 to week 51 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."

Tutorial Week: 45 - 51
One 10.0 hours tutorial per study period on weekdays during the day from week 45 to week 51 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments% ILO*
3-hour examination60 02, 05, 04, 03
In-class test, Pharmaceutical CalculationsHurdle requirement: must produce competent documentation and labels, must also achieve 70% in calculation test.10 05
Pharmaceutics practical skills30 04, 03, 02, 01

Singapore, 2016, Week 12-16, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJoy Spark

Class requirements

Laboratory Class Week: 12 - 16
One 15.0 hours laboratory class per study period on weekdays during the day from week 12 to week 16 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."

Lecture Week: 12 - 16
One 30.0 hours lecture per study period on weekdays during the day from week 12 to week 16 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."

Tutorial Week: 12 - 16
One 10.0 hours tutorial per study period on weekdays during the day from week 12 to week 16 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments% ILO*
3-hour examination60 02, 05, 04, 03
In-class test, Pharmaceutical CalculationsHurdle requirement: must produce competent documentation and labels, must also achieve 70% in calculation test.10 05
Pharmaceutics practical skills30 04, 03, 02, 01

Singapore, 2016, Week 12-16, Night

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorJoy Spark

Class requirements

Laboratory Class Week: 12 - 16
One 15.0 hours laboratory class per study period on weekdays at night from week 12 to week 16 and delivered via face-to-face.
"15-hours of Lab-Based Practical Class per teaching period delivered face-to-face or as directed online learning."

Lecture Week: 12 - 16
One 30.0 hours lecture per study period on weekdays at night from week 12 to week 16 and delivered via face-to-face.
"30-hours of Blended Lectures or Interactive Online Activities per teaching period delivered via face-to-face or online."

Tutorial Week: 12 - 16
One 10.0 hours tutorial per study period on weekdays at night from week 12 to week 16 and delivered via face-to-face.
"10-hours of Tutorial or Online Quizzes per teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments% ILO*
3-hour examination60 02, 05, 04, 03
In-class test, Pharmaceutical CalculationsHurdle requirement: must produce competent documentation and labels, must also achieve 70% in calculation test.10 05
Pharmaceutics practical skills30 04, 03, 02, 01