MEDICINAL AND ORGANIC CHEMISTRY

CHE2MOC

2016

Credit points: 15

Subject outline

This is an elective second year chemistry subject, which is taken in conjunction with CHE2FCA and involves lectures, tutorials, workshops and a laboratory component. This subject will include an introduction to medicinal chemistry, with an emphasis on how drugs interact with their molecular targets of lipids, carbohydrates, nucleic acids and proteins. Organic chemistry will focus on the properties, nomenclature, reactions and mechanisms of key functional groups used in organic synthesis, including the effects observed on stereochemistry.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorBelinda Abbott

Available to Study Abroad StudentsYes

Subject year levelYear Level 2 - UG

Exchange StudentsYes

Subject particulars

Subject rules

Prerequisites Either CHE1BAS or CHE1CHF or CHE1GEN, and CHE1APL

Co-requisites CHE2FCA

Incompatible subjects CHE2MEC

Equivalent subjectsN/A

Special conditionsN/A

Learning resources

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsIntroduction to Medicinal Chemistry, 4rd editionPrescribedPatrick, G.OXFORD UNIVERSITY PRESS, 2009.
ReadingsOrganic Chemistry, 9th edition, 2016PrescribedMcMurry, J.THOMSON-BROOKS/COLE

Graduate capabilities & intended learning outcomes

01. Explain the fundamental concepts of medicinal chemistry.

Activities:
During lectures students will answer short questions individually or as part of small groups, reinforcing lecture material. Students will work through problems that reinforce the concepts associated with this ILO individually. This material will be covered in tutorials and students will be required to orally explain their answers and participate in tutorial discussions. Written assignments will be used to reinforce and assess this ILO.

02. Illustrate understanding of the ways drugs interact with their molecular targets.

Activities:
During lectures students will answer short questions individually or as part of small groups, reinforcing lecture material. The concepts associated with this ILO will be reinforced using online quizzes, administered using LMS. Written assignments will be used to reinforce and assess this ILO.

03. Employ concepts of bonding to explain the properties of organic compounds.

Activities:
During lectures students will answer short questions individually or as part of small groups, reinforcing lecture material. Students will work through problems that reinforce the concepts associated with this ILO individually. This material will be covered in tutorials and students will be required to orally explain their answers and participate in tutorial discussions. The concepts associated with this ILO will be reinforced using online quizzes administered using LMS. Written assignments will be used to reinforce and assess this ILO.

04. Design synthetic schemes for the preparation of organic compounds showing understanding of reaction mechanisms.

Activities:
During lectures students will answer short questions individually or as part of small groups thereby reinforcing lecture material. Students will work through problems that reinforce the concepts associated with this ILO individually. This material will be covered in tutorials and students will be required to orally explain their answers and participate in tutorial discussions. The concepts associated with this ILO will be reinforced using online quizzes administered using LMS. Written assignments will be used to reinforce and assess this ILO.

05. Demonstrate practical skills needed to conduct chemical synthesis, chemical analysis and be able to interpret and report the results of spectroscopic measurements.

Activities:
Working individually or in small groups students will aquire practical skills required for the manipulation of chemicals for chemical synthesis. Working individually or in small groups students will learn techniques (chemical and instrumental) used in modern chemical analysis. Working individually or in small groups students will learn how to make spectroscopic measurements. Students will develop skills in the preparation of laboratory reports, including the use of correct and appropriate prose and presentation of experimental data and results.

Subject options

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Start date between: and    Key dates

Melbourne, 2016, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorBelinda Abbott

Class requirements

Tutorial Week: 10 - 22
One 1.0 hours tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Lecture Week: 10 - 22
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Laboratory Class Week: 10 - 22
One 3.0 hours laboratory class per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
LMS Quiz (0.5 hr)10 01, 02, 03, 04
Laboratory reports (equivalent to 1200 essay words)30 03, 05
Test (0.5 hr)10 01, 02, 03, 04
Topic exams (2 x 1.25 hr exams) or equivalent assessment tasks during semester50 01, 02, 03, 04