PHARMACOLOGY B

PHA2PGB

2015

Credit points: 15

Subject outline

This unit will introduce human molecular and population genetics and immunology. The immune responses from a cellular and molecular perspective will be investigated incorporating innate immunity, inflammation, chemical cascades, adaptive immunity and cells of the immune system. The subject will also cover activation and expression of the genome, DNA mutation and repair, DNA coding and recombination, and how genetic variation in the human population influences both the immune system and the phamacutical response.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorIan Swift

Available to Study Abroad StudentsYes

Subject year levelYear Level 2 - UG

Exchange StudentsYes

Subject particulars

Subject rules

Prerequisites BIO1CO or approval of the course co-ordinator.

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Special conditionsN/A

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsHuman GeneticsRecommendedLewis, R 20089TH ED MCGRAW-HILL. NEW YORK.
ReadingsImmunology-A Short CoursePreliminaryCoico, R and Sunshine, G 20086TH ED, WILEY-BLACKWELL

Graduate capabilities & intended learning outcomes

01. Describe how mutations in DNA can give rise to inherited genetic disorders, and what mechanisms exist to correct these mutations.

Activities:
The origins of DNA mutations; how there lead to the development of genetic diseases, and how such mutations can be corrected will be examined in lectures and reinforced in tutorials. Understanding will be assessed in the mid-semester test and final examination.
Related graduate capabilities and elements:
Quantitative Literacy/ Numeracy (Quantitative Literacy/ Numeracy)
Discipline-specific GCs (Discipline-specific GCs)
Critical Thinking (Critical Thinking)
Writing (Writing)

02. Explain in detail the process of inflammation and the steps involved in initiation of the immune response.

Activities:
The inflammatory process and immune response initiation will be explained in lectures and reinforced in tutorials. Understanding will be assessed in the final examination.
Related graduate capabilities and elements:
Quantitative Literacy/ Numeracy (Quantitative Literacy/ Numeracy)
Critical Thinking (Critical Thinking)
Writing (Writing)
Inquiry/ Research (Inquiry/ Research)
Discipline-specific GCs (Discipline-specific GCs)

03. Discuss how selected genetic traits are inherited in the human population and how this variation can be studied with an emphasis on multifactorial traits

Activities:
The distribution and analysis of certain genetic traits throughout the human population will be explained in lectures and reinforced in tutorials. The practical component will also examine some of these characteristics and their occurrence and distribution in the student cohort. Understanding will be assessed in the mid-semester test and final examination.
Related graduate capabilities and elements:
Writing (Writing)
Critical Thinking (Critical Thinking)
Quantitative Literacy/ Numeracy (Quantitative Literacy/ Numeracy)
Discipline-specific GCs (Discipline-specific GCs)

04. Describe how genetic variation in the human population leads to uniqueness of cells of the immune system.

Activities:
Activities: Lectures, tutorials, practical exercise. The genetic variation in several molecules of the immune recognition system will be presented in lectures. Understanding will be assessed in the final examnation.
Related graduate capabilities and elements:
Writing (Writing)
Quantitative Literacy/ Numeracy (Quantitative Literacy/ Numeracy)
Teamwork (Teamwork)
Discipline-specific GCs (Discipline-specific GCs)
Critical Thinking (Critical Thinking)
Inquiry/ Research (Inquiry/ Research)

Subject options

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Start date between: and    Key dates

Bendigo, 2015, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorIan Swift

Class requirements

Lecture Week: 31 - 43
Three 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Lecture/Tutorials Or Delivery Method: On-Line"

Tutorial Week: 31 - 43
One 1.0 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Or Type: Directed Learning Activity Or Delivery Method: On-Line"

Assessments

Assessment elementComments% ILO*
2-hour written examination60 01, 02, 03, 04
1-hour mid-semester test10 01, 02, 03, 04
One group review article (5000 words)30 01, 02, 03, 04

Singapore, 2015, Semester 2, Blended

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorIan Swift

Class requirements

Lecture/Film Week: 31 - 43
One 36.0 hours lecture/film per study period on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."

Tutorial Week: 31 - 43
One 12.0 hours tutorial per study period on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"12-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online."

Assessments

Assessment elementComments% ILO*
2-hour written examination60 01, 02, 03, 04
1-hour mid-semester test10 01, 02, 03, 04
One group review article (5000 words)30 01, 02, 03, 04