gen2mhg molecular genetics
MOLECULAR GENETICS
GEN2MHG
2015
Credit points: 15
Subject outline
This unit introduces students to concepts and methods in molecular and human genetics. Topics covered include: DNA and RNA structure, DNA replication, chromosome structure, transposable elements, transcription, translation, regulation of gene expression, recombination, DNA damage and repair, molecular biology and recombinant technologies, modes of inheritance, single and multigene diseases, epigenetic diseases, diagnosis of genetic diseases, gene therapy, personalised medicine, biotechnology and applications of genetic model organisms, bioinformatics, DNA in forensic sciences, synthetic life.
SchoolSchool of Molecular Sciences/LIMS
Credit points15
Subject Co-ordinatorChristine Hawkins
Available to Study Abroad StudentsYes
Subject year levelYear Level 2 - UG
Exchange StudentsYes
Subject particulars
Subject rules
Prerequisites BIO1GEN or BIO1MGC or BIO1EEB
Co-requisitesN/A
Incompatible subjects GEN2HMG
Equivalent subjectsN/A
Special conditionsN/A
Learning resources
Readings
| Resource Type | Title | Resource Requirement | Author and Year | Publisher |
|---|---|---|---|---|
| Readings | Concepts in Genetics, 10th Edition | Prescribed | Klug, Cummings, Spencer and Palladino, 2014 | Pearson Education |
| Readings | Human Molecular Genetics, 4th Edition | Recommended | Strachan, T and Read, A.P., 2011 | Garland Science |
Graduate capabilities & intended learning outcomes
01. Produce well-structured, scientifically accurate reports using grammatically correct English, which present evidence-based explanations of laboratory experiments.
- Activities:
- Extensive outline of the desired layout and contents of the written task are included in the practical manual. Part of a practical session prior to each report being submitted is dedicated to explaining to the students how to complete the task.
- Related graduate capabilities and elements:
- Quantitative Literacy/ Numeracy(Quantitative Literacy/ Numeracy)
- Inquiry/ Research(Inquiry/ Research)
- Critical Thinking(Critical Thinking)
- Discipline-specific GCs(Discipline-specific GCs)
- Writing(Writing)
02. As part of a team, deliver a clear, engaging and scientifically accurate oral presentation on a scientific topic you have researched.
- Activities:
- Part of a practical session is dedicated to teaching the students what constitutes a good oral presentation. Information is also included in the prac manual.
- Related graduate capabilities and elements:
- Discipline-specific GCs(Discipline-specific GCs)
- Inquiry/ Research(Inquiry/ Research)
- Speaking(Speaking)
03. Perform basic calculations required for design of molecular biology experiments.
- Activities:
- Students are given reading material and detailed instructions that describe the calculations they will perform. An unassessed on-line quiz is also provided for students to practice similar calculations, in preparation for undertaking the assessed worksheet.
- Related graduate capabilities and elements:
- Inquiry/ Research(Inquiry/ Research)
- Critical Thinking(Critical Thinking)
- Quantitative Literacy/ Numeracy(Quantitative Literacy/ Numeracy)
- Writing(Writing)
- Discipline-specific GCs(Discipline-specific GCs)
04. Demonstrate independent research skills by locating and evaluating relevant scientific information.
- Activities:
- Students are taught in a practical session how to search online databases for appropriate scientific literature.
- Related graduate capabilities and elements:
- Writing(Writing)
- Quantitative Literacy/ Numeracy(Quantitative Literacy/ Numeracy)
- Critical Thinking(Critical Thinking)
- Inquiry/ Research(Inquiry/ Research)
- Discipline-specific GCs(Discipline-specific GCs)
05. Place theoretical and/or experimental information into the appropriate discipline specific context.
- Activities:
- Students are taught to incorporate information from both lectures and practical sessions to make sound discipline - specific arguments in their scientific reports and theory exam.
- Related graduate capabilities and elements:
- Inquiry/ Research(Inquiry/ Research)
- Writing(Writing)
- Discipline-specific GCs(Discipline-specific GCs)
- Quantitative Literacy/ Numeracy(Quantitative Literacy/ Numeracy)
- Critical Thinking(Critical Thinking)
06. Understand and explain genetics concepts, including molecular mechanisms underpinning inheritance and expression of genetic traits.
- Activities:
- Working individually or in small groups students will learn how to interpret and evaluate genetics literature and concepts and apply their knowledge to solving discipline specific problems.
- Related graduate capabilities and elements:
- Writing(Writing)
- Quantitative Literacy/ Numeracy(Quantitative Literacy/ Numeracy)
- Inquiry/ Research(Inquiry/ Research)
- Discipline-specific GCs(Discipline-specific GCs)
- Critical Thinking(Critical Thinking)
07. Apply basic experimental molecular genetic techniques in research.
- Activities:
- In lectures, students are taught about the various techniques used in research and the rationale behind choosing a specific technique to address a particular question. In practical classes, the students participate in pairs or groups in hands-on experiments demonstrating those techniques.
- Related graduate capabilities and elements:
- Discipline-specific GCs(Discipline-specific GCs)
- Critical Thinking(Critical Thinking)
08. Apply knowledge of molecular structures and mechanisms to current medical, environmental and ethical issues related to genetics.
- Activities:
- In their oral presentation and exam, students integrate the information provided in formal lectures, guest lectures, workshops, reading material, self-guided learning and practical classes to recognise and understand the connections between molecular genetics and diverse aspects of society and biology.
- Related graduate capabilities and elements:
- Writing(Writing)
- Speaking(Speaking)
- Inquiry/ Research(Inquiry/ Research)
- Critical Thinking(Critical Thinking)
- Discipline-specific GCs(Discipline-specific GCs)
- Quantitative Literacy/ Numeracy(Quantitative Literacy/ Numeracy)
Subject options
Select to view your study options…
Melbourne, 2015, Semester 2, Day
Overview
Online enrolmentYes
Maximum enrolment size224
Enrolment information Availability of lab space Based on BIO1GEN, BIO1MGC or BIO1EEB grades
Subject Instance Co-ordinatorChristine Hawkins
Class requirements
Laboratory ClassWeek: 31 - 43
One 3.0 hours laboratory class per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Or Type: Directed Learning Activity Or Delivery Method: On-Line"
LectureWeek: 31 - 43
Three 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Or Delivery Method: On-Line"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| Worksheets | 17 | 01, 03, 04, 05, 06, 07 | |
| Practical reports (two) | 25 | 01, 03, 04, 05, 06, 07, 08 | |
| Oral presentation (10 min) | 7 | 02, 04, 05, 06, 08 | |
| On-line quizzes (weeks 2-12) | 11 | 05, 06, 07, 08 | |
| Exam (1.5 hour) | 40 | 05, 06, 08 |
Singapore, 2015, Semester 1, Blended
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorChristine Hawkins
Class requirements
Laboratory ClassWeek: 10 - 22
One 36.0 hours laboratory class per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"36-hours of Practical or Directed Learning Activities during the teaching period and delivered via face-to-face or online"
LectureWeek: 10 - 22
One 36.0 hours lecture per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| Worksheets | 17 | 01, 03, 04, 05, 06, 07 | |
| Practical reports (two) | 25 | 01, 03, 04, 05, 06, 07, 08 | |
| Oral presentation (10 min) | 7 | 02, 04, 05, 06, 08 | |
| On-line quizzes (weeks 2-12) | 11 | 05, 06, 07, 08 | |
| Exam (1.5 hour) | 40 | 05, 06, 08 |
Singapore, 2015, Week 45-49, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorChristine Hawkins
Class requirements
PracticalWeek: 45 - 49
One 36.0 hours practical per study period on weekdays during the day from week 45 to week 49 and delivered via blended.
"Consisting of wet/dry/simulation activities."
LectureWeek: 45 - 49
One 36.0 hours lecture per study period on weekdays during the day from week 45 to week 49 and delivered via blended.
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| Worksheets | 17 | 01, 03, 04, 05, 06, 07 | |
| Practical reports (two) | 25 | 01, 03, 04, 05, 06, 07, 08 | |
| Oral presentation (10 min) | 7 | 02, 04, 05, 06, 08 | |
| On-line quizzes (weeks 2-12) | 11 | 05, 06, 07, 08 | |
| Exam (1.5 hour) | 40 | 05, 06, 08 |
Singapore, 2015, Week 45-49, Night
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorChristine Hawkins
Class requirements
PracticalWeek: 45 - 49
One 36.0 hours practical per study period on weekdays at night from week 45 to week 49 and delivered via face-to-face.
"Consisting of we/dry/simulation activies."
LectureWeek: 45 - 49
One 36.0 hours lecture per study period on weekdays at night from week 45 to week 49 and delivered via face-to-face.
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| Worksheets | 17 | 01, 03, 04, 05, 06, 07 | |
| Practical reports (two) | 25 | 01, 03, 04, 05, 06, 07, 08 | |
| Oral presentation (10 min) | 7 | 02, 04, 05, 06, 08 | |
| On-line quizzes (weeks 2-12) | 11 | 05, 06, 07, 08 | |
| Exam (1.5 hour) | 40 | 05, 06, 08 |