MEDICINAL CHEMISTRY A

CHE2MCA

2020

Credit points: 15

Subject outline

Students will be introduced to the chemical principles that are required to understand the action and behaviours of a drug compound. The main areas of study include an introduction to the chemistry and nomenclature of carbohydrates, lipids, steroids and heterocyclic compounds and some of their reactions. This unit will provide an understanding of how the chemical structure and behaviour of drug molecules relate to the activity of drugs in biological systems, and how this knowledge can be used to devise strategies for drug design and principles of drug structure-activity relationships (SAR and QSAR), drug-receptor interactions and drugs metabolism. This unit will also contain a computer based practical component.

School: Molecular Sciences (Pre 2022)

Credit points: 15

Subject Co-ordinator: Jasim Al-Rawi

Available to Study Abroad/Exchange Students: Yes

Subject year level: Year Level 2 - UG

Available as Elective: No

Learning Activities: N/A

Capstone subject: No

Subject particulars

Subject rules

Prerequisites: (CHE1C1B AND CHE1C1A) OR (CHE1CHF AND CHE1APL)

Co-requisites: N/A

Incompatible subjects: N/A

Equivalent subjects: N/A

Quota Management Strategy: N/A

Quota-conditions or rules: N/A

Special conditions: N/A

Minimum credit point requirement: N/A

Assumed knowledge: N/A

Learning resources

Medicinal Chemistry: An Introduction

Resource Type: Book

Resource Requirement: Recommended

Author: Thomas, G.

Year: 2007

Edition/Volume: N/A

Publisher: Wiley

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Organic chemistry

Resource Type: Book

Resource Requirement: Prescribed

Author: Bruice, P. Y.

Year: 2017

Edition/Volume: N/A

Publisher: Pearson

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

An Introduction to Medicinal Chemistry

Resource Type: Book

Resource Requirement: Prescribed

Author: Patrick, G.

Year: 2013

Edition/Volume: N/A

Publisher: Oxford University Press

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Career Ready

Career-focused: No

Work-based learning: No

Self sourced or Uni sourced: N/A

Entire subject or partial subject: N/A

Total hours/days required: N/A

Location of WBL activity (region): N/A

WBL addtional requirements: N/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Apply understanding of the chemistry of important biological molecules such as carbohydrates, lipids, steroids and heterocyclic molecules to medicinal products.
02. Apply advanced understanding of the chemistry of organic compounds and its impact on syntheses to enhance drug efficacy.
03. Use the major concepts and language of pharmaceutical and medicinal chemistry correctly.
04. Determine likely routes of administration through recognition of drug structures, identification and prediction of likely metabolic and elimination pathways, solubility and metabolism.
05. Devise strategies for drug design and principles of drug structure-activity relationships (SAR and QSAR).

Albury-Wodonga, 2020, Semester 1, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Keith White

Class requirements

Computer LaboratoryWeek: 13 - 16
One 3.00 hours computer laboratory per study period on weekdays during the day from week 13 to week 16 and delivered via face-to-face.
Computer Laboratory simulation

LectureWeek: 10 - 22
Three 1.00 hour lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

PracticalWeek: 15 - 15
One 3.00 hours practical per study period on weekdays during the day from week 15 to week 15 and delivered via face-to-face.

TutorialWeek: 11 - 22
One 1.00 hour tutorial per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

One 3-hour end-of-semester written examination (3,000-words equivalent)

N/AN/AN/ANo60SILO1, SILO2, SILO3, SILO4, SILO5

Two in-class tests (15% each) (600-words equivalent in total)

N/AN/AN/ANo30SILO1, SILO2, SILO3

Two laboratory reports (5% each) (300-words equivalent in total)

N/AN/AN/ANo10SILO2, SILO3

Bendigo, 2020, Semester 1, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jasim Al-Rawi

Class requirements

Computer LaboratoryWeek: 13 - 16
One 3.00 hours computer laboratory per study period on weekdays during the day from week 13 to week 16 and delivered via face-to-face.
Computer Laboratory simulation

LectureWeek: 10 - 22
Three 1.00 hour lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

PracticalWeek: 15 - 15
One 3.00 hours practical per study period on weekdays during the day from week 15 to week 15 and delivered via face-to-face.

TutorialWeek: 11 - 22
One 1.00 hour tutorial per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

One 3-hour end-of-semester written examination (3,000-words equivalent)

N/AN/AN/ANo60SILO1, SILO2, SILO3, SILO4, SILO5

Two in-class tests (15% each) (600-words equivalent in total)

N/AN/AN/ANo30SILO1, SILO2, SILO3

Two laboratory reports (5% each) (300-words equivalent in total)

N/AN/AN/ANo10SILO2, SILO3

Singapore (PSB), 2020, Term 2, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

Computer LaboratoryWeek: 21 - 31
One 3.00 hours computer laboratory per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.

LectureWeek: 21 - 31
Thirty six 1.00 hour lecture per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.
36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

PracticalWeek: 21 - 31
One 3.00 hours practical per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.

TutorialWeek: 21 - 31
Twelve 1.00 hour tutorial per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.
12-hours of tutorials or online quizzes during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

One 3-hour end-of-semester written examination (3,000-words equivalent)

N/AN/AN/ANo60SILO1, SILO2, SILO3, SILO4, SILO5

Two in-class tests (15% each) (600-words equivalent in total)

N/AN/AN/ANo30SILO1, SILO2, SILO3

Two laboratory reports (5% each) (300-words equivalent in total)

N/AN/AN/ANo10SILO2, SILO3

Singapore (PSB), 2020, Term 2, Night

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

Computer LaboratoryWeek: 21 - 31
One 3.00 hours computer laboratory per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.

LectureWeek: 21 - 31
Thirty six 1.00 hour lecture per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.
36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

PracticalWeek: 21 - 31
One 3.00 hours practical per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.

TutorialWeek: 21 - 31
Twelve 1.00 hour tutorial per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.
12-hours of tutorials or online quizzes during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

One 3-hour end-of-semester written examination (3,000-words equivalent)

N/AN/AN/ANo60SILO1, SILO2, SILO3, SILO4, SILO5

Two in-class tests (15% each) (600-words equivalent in total)

N/AN/AN/ANo30SILO1, SILO2, SILO3

Two laboratory reports (5% each) (300-words equivalent in total)

N/AN/AN/ANo10SILO2, SILO3

Singapore (PSB), 2020, Term 3, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

Computer LaboratoryWeek: 37 - 47
One 3.00 hours computer laboratory per study period on weekdays during the day from week 37 to week 47 and delivered via face-to-face.

LectureWeek: 37 - 47
Thirty six 1.00 hour lecture per study period on weekdays during the day from week 37 to week 47 and delivered via face-to-face.
36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

PracticalWeek: 37 - 47
One 3.00 hours practical per study period on weekdays during the day from week 37 to week 47 and delivered via face-to-face.

TutorialWeek: 37 - 47
Twelve 1.00 hour tutorial per study period on weekdays during the day from week 37 to week 47 and delivered via face-to-face.
12-hours of tutorials or online quizzes during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

One 3-hour end-of-semester written examination (3,000-words equivalent)

N/AN/AN/ANo60SILO1, SILO2, SILO3, SILO4, SILO5

Two in-class tests (15% each) (600-words equivalent in total)

N/AN/AN/ANo30SILO1, SILO2, SILO3

Two laboratory reports (5% each) (300-words equivalent in total)

N/AN/AN/ANo10SILO2, SILO3

Singapore (PSB), 2020, Term L3 , Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

Computer LaboratoryWeek: 19 - 23
One 3.00 hours computer laboratory per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.

LectureWeek: 19 - 23
Thirty six 1.00 hour lecture per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

PracticalWeek: 19 - 23
One 3.00 hours practical per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.

TutorialWeek: 19 - 23
Twelve 1.00 hour tutorial per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
12-hours of tutorials or online quizzes during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

One 3-hour end-of-semester written examination (3,000-words equivalent)

N/AN/AN/ANo60SILO1, SILO2, SILO3, SILO4, SILO5

Two in-class tests (15% each) (600-words equivalent in total)

N/AN/AN/ANo30SILO1, SILO2, SILO3

Two laboratory reports (5% each) (300-words equivalent in total)

N/AN/AN/ANo10SILO2, SILO3

Singapore (PSB), 2020, Term L3 , Night

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

Computer LaboratoryWeek: 19 - 23
One 3.00 hours computer laboratory per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.

LectureWeek: 19 - 23
Thirty six 1.00 hour lecture per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

PracticalWeek: 19 - 23
One 3.00 hours practical per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.

TutorialWeek: 19 - 23
Twelve 1.00 hour tutorial per study period on weekdays during the day from week 19 to week 23 and delivered via face-to-face.
12-hours of tutorials or online quizzes during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

One 3-hour end-of-semester written examination (3,000-words equivalent)

N/AN/AN/ANo60SILO1, SILO2, SILO3, SILO4, SILO5

Two in-class tests (15% each) (600-words equivalent in total)

N/AN/AN/ANo30SILO1, SILO2, SILO3

Two laboratory reports (5% each) (300-words equivalent in total)

N/AN/AN/ANo10SILO2, SILO3