gen3mgg molecular genetics theory
MOLECULAR GENETICS AND GENOMICS
GEN3MGG
2019
Credit points: 15
Subject outline
Molecular Genetics and Genomics introduces students to advanced concepts in modern molecular genetics and genomics. The topics covered in this subject include the genetic regulation of normal development and genetic disease; stem cells and regenerative medicine; Cancer and molecular medicine; Model organisms for modelling Human genetic diseases, including Mice and fruit fly; Immuno-genetics; Forensic genetics; Genomics, bioinformatics and gene therapy. A large part of this blended subject involves problem based learning, where students work through online Genetics case studies, bioinformatics projects and scientific literature analyses, which provide the conceptual basis for face to face workshops.
SchoolSchool of Molecular Sciences/LIMS
Credit points15
Subject Co-ordinatorJames Tsatsaronis
Available to Study Abroad StudentsYes
Subject year levelYear Level 3 - UG
Exchange StudentsYes
Subject particulars
Subject rules
Prerequisites GEN2MHG
Co-requisitesN/A
Incompatible subjects GEN3HMG
Equivalent subjectsN/A
Special conditionsN/A
Learning resources
Readings
| Resource Type | Title | Resource Requirement | Author and Year | Publisher |
|---|---|---|---|---|
| Readings | Genetics Analysis and Principles | Recommended | Brooker, R | MCGRAW HILL 2011 |
| Readings | Human Embryology and developmental | Recommended | Carlson, B | ELSEVIER 2013 |
| Readings | Human Evolutionary Genetics | Recommended | Jobling M.A, Hurles. M and Tyler-Smith C | GARLAND SCIENCE 2004 |
| Readings | Human Molecular Genetics 4th Edition | Recommended | Strachan, T and Read, A.P. | GARLAND SCIENCE 2011 |
| Readings | Principle of Development | Recommended | Wolpert, L and Tickle C | OXFORD 2010 |
| Readings | Janeway's Immunobiology 7th edition | Recommended | Murphy, Travers and Walport | Garland Science |
| Readings | Concepts of Genetics, 10th, international edition | Recommended | Klug et. al., | Pearson |
Graduate capabilities & intended learning outcomes
01. Analyse and evaluate experimental and published data relating to molecular genetics experiments to prepare a comprehensive literature review.
- Activities:
- A research topic related to the subject intended learning outcomes will be selected by the student. Online training in evidence based research review writing will be provided online and workshopped. Students will also receive online training in the use of referencing software and receive a round of written feedback before submitting a 500 word literature review via turnitin.
- Related graduate capabilities and elements:
- Literacies and Communication Skills(Writing,Speaking,Quantitative Literacy)
- Literacies and Communication Skills(Writing,Speaking,Quantitative Literacy)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Personal and Professional Skills(Teamwork including leadership and working in groups,Ethical behaviour,Study and Learning Skills)
- Discipline -Specific Knowledge and Skills(Discipline-Specific Knowledge and Skills)
02. Articulate and apply advanced genetics theory and analytical methods in the genetic control of development, the structure and function of genes and chromosomes, human variation, genetic disease and genome biology.
- Activities:
- Genetics concepts and analytical methods are explained in lectures and recommended reading. Students participate in theory revision sessions. Students can revise content and practice their knowledge via online resources (LMS quizzes Peerwise) including: practice exam questions, discussion groups, lectopia and other materials. Students attempt 2 in- class multiple choice exams and can use the feedback on these exams to structure their revision before the end-of- semester examination (2 x 1.5 hour theory exam)
- Related graduate capabilities and elements:
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Discipline -Specific Knowledge and Skills(Discipline-Specific Knowledge and Skills)
03. Use bioinformatics to solve genetics problems.
- Activities:
- Information to complete assignments will be available online. Individually, students will access online worksheets, tutorials, genome databases and bioinformatics tools to solve genetics problems: - Students have to complete bioinformatics worksheets using online tutorials and database mining tools. - Students perform DNA sequence analysis online to identify disease related DNA polymorphisms and to design molecular clinical diagnostic tests- Students use online databases and apply gene search and analysis tools to analyse clinical case study data.
- Related graduate capabilities and elements:
- Literacies and Communication Skills(Writing,Speaking,Quantitative Literacy)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Personal and Professional Skills(Teamwork including leadership and working in groups,Ethical behaviour,Study and Learning Skills)
- Discipline -Specific Knowledge and Skills(Discipline-Specific Knowledge and Skills)
04. Apply clinical problem solving skills to diagnose genetic diseases.
- Activities:
- An online problem solving clinical case study activity is followed by a formative learning quiz. Study questions and student online feedback arising from the online case study is then discussed in a workshop. An assessed quiz is then taken online to test knowledge. Six case studies will be conducted and students will select one to create a case study poster that is also assessed. Written feedback on the posters is given by peers and academics.
- Related graduate capabilities and elements:
- Literacies and Communication Skills(Writing,Speaking,Quantitative Literacy)
- Literacies and Communication Skills(Writing,Speaking,Quantitative Literacy)
- Literacies and Communication Skills(Writing,Speaking,Quantitative Literacy)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Inquiry and Analytical Skills(Critical Thinking,Creative Problem-solving,Inquiry/Research)
- Personal and Professional Skills(Teamwork including leadership and working in groups,Ethical behaviour,Study and Learning Skills)
- Personal and Professional Skills(Teamwork including leadership and working in groups,Ethical behaviour,Study and Learning Skills)
- Personal and Professional Skills(Teamwork including leadership and working in groups,Ethical behaviour,Study and Learning Skills)
- Discipline -Specific Knowledge and Skills(Discipline-Specific Knowledge and Skills)
Subject options
Select to view your study options…
Melbourne, 2019, Semester 1, Blended
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorJames Tsatsaronis
Class requirements
Unscheduled Online ClassWeek: 10 - 22
One 2.0 hours unscheduled online class per week on weekdays during the day from week 10 to week 22 and delivered via blended.
"Online Lectorial and knowledge test quiz followed by online activity and assessment"
Lecture/WorkshopWeek: 10 - 22
One 2.0 hours lecture/workshop per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"Lecture and knowledge test quiz followed by problem based workshop and assessment."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| Weekly online activity and quiz (900 words equivalent) | 20 | 02 | |
| Case study online quizzes & case study poster (600 words equivalent) | 14 | 01, 02, 04 | |
| Literature review and bioinformatics worksheets (1000 words) | 26 | 01, 02, 03, 04 | |
| One 2-hour exam at end of semester (1800 words equivalent) | 40 | 02 |
Singapore (PSB), 2019, Term L6, Day
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorNoni Frankenberg
Class requirements
Unscheduled Online ClassWeek: 44 - 48
One 24.0 hours unscheduled online class per study period on weekdays during the day from week 44 to week 48 and delivered via blended.
"Online Lectorial and knowledge test quiz followed by online activity and assessment"
Lecture/WorkshopWeek: 44 - 48
One 24.0 hours lecture/workshop per study period on weekdays during the day from week 44 to week 48 and delivered via blended.
"Lecture and knowledge test quiz followed by problem based workshop and assessment."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| Weekly online activity and quiz (900 words equivalent) | 20 | 02 | |
| Case study online quizzes & case study poster (600 words equivalent) | 14 | 01, 02, 04 | |
| Literature review and bioinformatics worksheets (1000 words) | 26 | 01, 02, 03, 04 | |
| One 2-hour exam at end of semester (1800 words equivalent) | 40 | 02 |
Singapore (PSB), 2019, Term L6, Night
Overview
Online enrolmentYes
Maximum enrolment sizeN/A
Enrolment information
Subject Instance Co-ordinatorNoni Frankenberg
Class requirements
Unscheduled Online ClassWeek: 44 - 48
One 24.0 hours unscheduled online class per study period on weekdays at night from week 44 to week 48 and delivered via blended.
"Online Lectorial and knowledge test quiz followed by online activity and assessment"
Lecture/WorkshopWeek: 44 - 48
One 24.0 hours lecture/workshop per study period on weekdays at night from week 44 to week 48 and delivered via blended.
"Lecture and knowledge test quiz followed by problem based workshop and assessment"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| Weekly online activity and quiz (900 words equivalent) | 20 | 02 | |
| Case study online quizzes & case study poster (600 words equivalent) | 14 | 01, 02, 04 | |
| Literature review and bioinformatics worksheets (1000 words) | 26 | 01, 02, 03, 04 | |
| One 2-hour exam at end of semester (1800 words equivalent) | 40 | 02 |