MEDICINAL CHEMISTRY C

CHE3MCC

2017

Credit points: 30

Subject outline

CHE3MCC is a core 3rd year subject required for a Medicinal Chemistry major, along with CHE3MCD. Learning activities within the subject include lectures, tutorials, workshops and laboratory classes. Core topics address the areas of bioinorganic and medicinal chemistry, organic synthesis and techniques for chemical analysis (e.g. nuclear magnetic resonance, mass spectrometry, separation science, atomic spectroscopy). One optional topic must also be selected, from areas such as bonding, sustainability and chemistry, polymer chemistry.

SchoolSchool of Molecular Sciences/LIMS

Credit points30

Subject Co-ordinatorConor Hogan

Available to Study Abroad StudentsYes

Subject year levelYear Level 3 - UG

Exchange StudentsYes

Subject particulars

Subject rules

Prerequisites Admission into SBMC and either (CHE2FCA and CHE2FCB and CHE2MOC) or CHE2MEC.

Co-requisitesN/A

Incompatible subjects CHE3ADA

Equivalent subjectsN/A

Special conditions Optional topics may vary from year to year.

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsOrganic ChemistryPrescribedMcMurry, J., 2016Thomson-Brookes/Cole
ReadingsQuantitative Chemical AnalysisPrescribedHarris, D.C., 2010Freeman
ReadingsSpectrometric Identification of Organic CompoundsPrescribedSilverstein, Webster & Kiemle, 2005Wiley
ReadingsPhysical ChemistryRecommendedAtkins, P and de Paula, J., 2010Oxford University Press
ReadingsChemistry in ContextRecommendedAnderson, Middlecamp and Cann, 2011McGraw-Hill

Graduate capabilities & intended learning outcomes

01. Demonstrate thorough understanding of "Key Principles of Chemistry" as defined by the Royal Australian Chemical Institute and employ experimental methods of investigation of the defined principles.

Activities:
During lectures students will answer short questions individually or as part of small groups, reinforcing lecture material. In tutorials and in their own time students will apply these concepts to solve a variety of problems, some of which are assessed via quizzes or assignments and others which are provided as optional problem sets for exam preparation.
Related graduate capabilities and elements:
Literacies and Communication Skills (Writing,Speaking,Quantitative Literacy)

02. Apply professional integrity and safe laboratory practices when designing and performing experiments, colecting data and reporting results, in order to satisfy the professional accreditation requirements of the Royal Australian Chemical Institute.

Activities:
Students are explicitly briefed on safe laboratory practices and given an assignment on risk assessment and use of material safety data sheets. Working individually or in small groups, students will aquire practical skills required for the manipulation of chemicals for chemical synthesis and learn how to use modern instrumentation to perform chemical analyses. Student laboratory reports and assignments are compared to ensure authenticity and mark allocation or penalty applied.
Related graduate capabilities and elements:
Literacies and Communication Skills (Writing,Speaking,Quantitative Literacy)

03. Apply relevant mathematical, graphical and computational methods to acquire, manipulate, interpret and evaluate chemical data and summarise results using appropriate significant figures and units.

Activities:
Student calculations are submitted in subject assignments, laboratory reports and exams and are assessed for accuracy of result and logical structure. The evaluation and reporting of errors and uncertainties is particularly dealt with in the laboratory assessment.
Related graduate capabilities and elements:
Literacies and Communication Skills (Writing,Speaking,Quantitative Literacy)

04. Write coherent descriptions of chemical principles and report experimental results with well supported interpretations using correctly referenced professional prose.

Activities:
Laboratory reports: students submit laboratory reports throughout the semester that are marked against a rubric for professional presentation. Reports returned in a timely manner and annotated with helpful comments to aid improvement. Topic assignments: students submit topic assignments throughout the semester that are marked against a rubric for professional prose and accurate description of information including references where appropriate. Assignments returned and annotated with helpful comments to aid improvement.
Related graduate capabilities and elements:
Literacies and Communication Skills (Writing,Speaking,Quantitative Literacy)

05. Solve abstract, routine and real-world problems of chemical relevance by sourcing, collating and summarising legitimate scientific information.

Activities:
In tutorial problem classes and assignments students must apply chemical concepts to solve a variety of problems and draw from appropriate chemical data sources to do so. In the laboratory context, a referencing and databases assignment trains students in using the chemical literature.
Related graduate capabilities and elements:
Literacies and Communication Skills (Writing,Speaking,Quantitative Literacy)

06. Orally present chemistry matters, supported by legitimate evidence and appropriately defended to peers or professionals.

Activities:
Students will be expected to orally explain their answers and participate in tutorial discussions on a regular basis. Students present a 10-minute seminar on a completed laboratory experiment that is assessed against a rubric for professional prose, presentation of information and data, critical evaluation and summary of results.
Related graduate capabilities and elements:
Literacies and Communication Skills (Writing,Speaking,Quantitative Literacy)

Subject options

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Start date between: and    Key dates

Melbourne, 2017, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorConor Hogan

Class requirements

Laboratory Class Week: 10 - 22
One 5.0 hours laboratory class per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"Students attend 8 wet lab sessions and additional learning activities as required."

Lecture/Workshop Week: 10 - 22
Five 1.0 hours lecture/workshop per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"All students attend 4 core topics and choose 1 additional topic from the electives offered."

Tutorial Week: 10 - 22
One 1.0 hours tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
Assignments (equivalent to 2000 words in total)Tasks to be completed during semester which are designed to help students master concepts and solve chemistry problems.25 01, 03, 04, 05
Laboratory work, written reports and an oral report (equivalent to 2500 words)Develops and assess competency in practical skills, and in data handling and reporting. A hurdle requirement of 50% applies to the lab component.30 01, 02, 03, 04, 05, 06
Examinations (equivalent to 4500 words)A 2.5 hour paper on core topics, and 2 hour paper on the elective topics. A hurdle requirement of 50% applies to the exam component.45 01, 03, 04, 05