BIOPHARMACEUTICS
CHE3BPH
2016
Credit points: 15
Subject outline
Drugsare used in a wide range of dosage forms and pharmacists need to understand thedesign and rationale behind available dosage forms. Also, in order to properlyadvise patients on the use of drugs it is necessary to understand themechanisms by which the drugs are absorbed and interact in the body. Fundamental principles of biopharmaceutics arediscussed with emphasis on the qualitative and quantitative description offactors which influence drug disposition. Drugs are used in a wide range ofdosage forms and pharmacists need to understand the design and rationale behindthese available dosage forms. We will investigate different types offormulation and how the ingredients in a formulation together with method ofmanufacture, can influence the bioavailability of a drug within the body.
School: School of Molecular Sciences/LIMS
Credit points: 15
Subject Co-ordinator: David Morton
Available to Study Abroad Students: Yes
Subject year level: Year Level 3 - UG
Exchange Students: Yes
Subject particulars
Subject rules
Prerequisites: PHA1PFA or CHE2MCA
Co-requisites: N/A
Incompatible subjects: N/A
Equivalent subjects: N/A
Special conditions: N/A
Learning resources
Readings
| Resource Type | Title | Resource Requirement | Author and Year | Publisher |
|---|---|---|---|---|
| Readings | Aulton's Pharmaceutics: the Design and Manufacture of Medicines | Recommended | Aulton, ME (ed.) 2013 | 4th ed., London: Churchill |
| Readings | Applied Biopharmaceutics & Pharmacokinetics | Prescribed | Shargel, L.; Wu-Pong, S.; Yu, A. (2012) | 6th ed., New York, McGraw Hill |
| Readings | Concepts in Clinical Pharmacokinetics | Recommended | DiPiro et al. (2005) | 4th ed. Bethesda, ASHSP |
Graduate capabilities & intended learning outcomes
01. Evaluate the inclusion and function of all the ingredients in different formulations.
- Activities:
- The key concepts to be integrated are discussed in both lectures and workshops. Workshops are opportunities for students to problem solve and are designed to be interactive.
- Related graduate capabilities and elements:
- Critical Thinking(Critical Thinking)
- Discipline-specific GCs(Discipline-specific GCs)
- Creative Problem-solving(Creative Problem-solving)
02. Advise on and discuss the limitations and restrictions on different excipients used in pharmaceutical formulations.
- Activities:
- The key concepts to be integrated are discussed in both lectures and workshops. Workshops are opportunities for students to problem solve and are designed to be interactive.
- Related graduate capabilities and elements:
- Inquiry/ Research(Inquiry/ Research)
- Creative Problem-solving(Creative Problem-solving)
- Critical Thinking(Critical Thinking)
03. Explain how the use of pharmacokinetics can be used to predict drug disposition and assist in effective drug therapy.
- Activities:
- The key concepts to be integrated are discussed in both lectures and workshops. Workshops are opportunities for students to problem solve and are designed to be interactive.
- Related graduate capabilities and elements:
- Inquiry/ Research(Inquiry/ Research)
- Critical Thinking(Critical Thinking)
- Creative Problem-solving(Creative Problem-solving)
04. Interpret pharmacokinetic calculation problems and solve them accurately.
- Activities:
- The key concepts to be integrated are discussed in both lectures and workshops. Workshops are opportunities for students to problem solve and are designed to be interactive.
- Related graduate capabilities and elements:
- Critical Thinking(Critical Thinking)
- Inquiry/ Research(Inquiry/ Research)
- Discipline-specific GCs(Discipline-specific GCs)
- Creative Problem-solving(Creative Problem-solving)
05. Assess the effects of excipients and the type dosage form used on the bioavailability of a drug.
- Activities:
- The key concepts to be integrated are discussed in both lectures and workshops. Workshops are opportunities for students to problem solve and are designed to be interactive.
- Related graduate capabilities and elements:
- Creative Problem-solving(Creative Problem-solving)
Bendigo, 2016, Semester 1, Day
Overview
Online enrolment: Yes
Maximum enrolment size: N/A
Enrolment information:
Subject Instance Co-ordinator: David Morton
Class requirements
TutorialWeek: 10 - 22
One 2.0 hours tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"Or Type: Directed Learning Activity Or Delivery Method: On-Line"
LectureWeek: 10 - 22
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"Or Delivery Method: On-Line"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 05, 03, 01, 02 | |
| Assignment (1,500 words) | 20 | 01, 02, 04, 05 | |
| 2 class tests (50 minutes each) | 20 | 01, 04 |
Malaysia, 2016, Semester 1, Day
Overview
Online enrolment: Yes
Maximum enrolment size: N/A
Enrolment information:
Subject Instance Co-ordinator: David Morton
Class requirements
TutorialWeek: 10 - 22
One 2.0 hours tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"Or Type: Directed Learning Activity Or Delivery Method: On-Line"
LectureWeek: 10 - 22
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"Or Delivery Method: On-Line"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 05, 03, 01, 02 | |
| Assignment (1,500 words) | 20 | 01, 02, 04, 05 | |
| 2 class tests (50 minutes each) | 20 | 01, 04 |
Malaysia, 2016, Semester 2, Day
Overview
Online enrolment: Yes
Maximum enrolment size: N/A
Enrolment information:
Subject Instance Co-ordinator: David Morton
Class requirements
TutorialWeek: 31 - 43
One 2.0 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Or Type: Directed Learning Activity Or Delivery Method: On-Line"
LectureWeek: 31 - 43
Two 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Or Delivery Method: On-Line"
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 05, 03, 01, 02 | |
| Assignment (1,500 words) | 20 | 01, 02, 04, 05 | |
| 2 class tests (50 minutes each) | 20 | 01, 04 |
Singapore, 2016, Week 28-31, Day
Overview
Online enrolment: Yes
Maximum enrolment size: N/A
Enrolment information:
Subject Instance Co-ordinator: David Morton
Class requirements
LectureWeek: 28 - 31
One 24.0 hours lecture per study period on weekdays during the day from week 28 to week 31 and delivered via face-to-face.
"Equivalent of 24-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."
TutorialWeek: 28 - 31
One 24.0 hours tutorial per study period on weekdays during the day from week 28 to week 31 and delivered via face-to-face.
"24-hours of Directed Learning Activities during the teaching period and delivered via face-to-face or online."
Assessments
| Assessment element | Comments | % | ILO* |
|---|---|---|---|
| 3-hour examination | 60 | 05, 03, 01, 02 | |
| Assignment (1,500 words) | 20 | 01, 02, 04, 05 | |
| 2 class tests (50 minutes each) | 20 | 01, 04 |