PHARMACEUTICAL FORMULATION B

PHA2PFB

2015

Credit points: 15

Subject outline

Pharmacists dispense many dosage forms and need to understand their strengths and limitations. Students will be taught the design and formulation of two-phase pharmaceutical products including suspensions and emulsions. Major topics include: pharmaceutically relevant physicochemical phenomena, quality assurance, preparation and extemporaneous dispensing of pharmaceutical preparations, including pharmaceutical calculations.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorChristina Dennis

Available to Study Abroad StudentsNo

Subject year levelYear Level 2 - UG

Exchange StudentsNo

Subject particulars

Subject rules

Prerequisites PHA1PFA. Only available to students enrolled in the Bachelor of Pharmacy course (SVPB or SBPM or SHPM or SBPB or SHPB).

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Special conditions A satisfactory placement, report and/or manual is required to pass this subject. Students must have a current Police check and Working with Children check before attending placement.

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsAulton's Pharmaceutics: the design and manufacture of medicinesPrescribedAulton, ME and Taylor, K. 20134TH ED., LONDON: CHURCHILL LIVINGSTONE
ReadingsAustralian Pharmaceutical Formulary and Handbook 2012PrescribedTBA22ND ED., CANBERRA: PHARMACEUTICAL SOCIETY OF AUSTRALIA, 2012.
ReadingsMartindale: the complete drug referenceRecommendedTBA38TH ED., 2014 LONDON: PHARMACEUTICAL PRESS
ReadingsPharmaceutical PracticeRecommendedRees JA, Smith, I. and Watson J 20145TH ED., LONDON: CHURCHILL LIVINGSTONE
ReadingsPhysicochemical Principles of PharmacyRecommendedFlorence, AT& Attwood, D 20115TH ED., BASINGSTOKE: MACMILLAN

Graduate capabilities & intended learning outcomes

01. Meet the PSA Professional Practice Standard for Compounding by preparing and dispensing extemporaneous products.

Activities:
Activity: Tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, including exam. Students must prepare and dispense solution and two-phase formulations. Marks are awarded for labelling accuracy, elegance of product. Quality assurance protocols are used throughout, and students must be able to self-assess the quality of their products.
Related graduate capabilities and elements:
Critical Thinking (Critical Thinking)
Discipline-specific GCs (Discipline-specific GCs)
Ethical Awareness (Ethical Awareness)

02. Explain and predict the properties of 2-phase systems and discuss their formulation.

Activities:
Activity: Lectures, tutorials, problem sheet questions, practical work. Assessment: Assessed in the written exam and practical skills assessment. Questions on these assessments contain physiochemical and formulation information that must be used to predict the behaviour of gels, suspensions, or emulsion systems. On the exam students must be able to use their knowledge of the science behind 2-phase systems to complete the problems.
Related graduate capabilities and elements:
Critical Thinking (Critical Thinking)
Creative Problem-solving (Creative Problem-solving)
Ethical Awareness (Ethical Awareness)
Discipline-specific GCs (Discipline-specific GCs)

03. Use knowledge of topical formulations to justify the selection of an appropriate topical product for a specified use.

Activities:
Activity: Lectures, tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, which includes an oral component, written exam. In these assessments students are asked to select an appropriate topical product for an application and justify this choice.
Related graduate capabilities and elements:
Discipline-specific GCs (Discipline-specific GCs)
Speaking (Speaking)
Critical Thinking (Critical Thinking)
Ethical Awareness (Ethical Awareness)
Creative Problem-solving (Creative Problem-solving)

04. Accurately perform basic pharmaceutical calculations.

Activities:
Activity: Lectures, tutorials, on-line quiz bank. Assessment: Students should successfully complete the on-line quizzes and then sit a final test where they must achieve a score of 90% to pass the subject. The questionbank is accessible via the LMS - students can repeat quizzes as often as they like. A Question and Answer forum is set up to encourage collaborative problem-solving. There is also a dedicated tutorial for calculations and problem-solving.
Related graduate capabilities and elements:
Critical Thinking (Critical Thinking)
Creative Problem-solving (Creative Problem-solving)
Discipline-specific GCs (Discipline-specific GCs)
Quantitative Literacy/ Numeracy (Quantitative Literacy/ Numeracy)

05. Discuss factors affecting drug stability and how these influence the choice of dosage form and packaging as well as application of quality assurance to compounded products.

Activities:
Activity: Lectures, tutorials. Assessment: Written exam and practical interview.
Related graduate capabilities and elements:
Critical Thinking (Critical Thinking)
Creative Problem-solving (Creative Problem-solving)
Discipline-specific GCs (Discipline-specific GCs)

06. Discuss the mechanisms in place to ensure professional efficient running of a pharmacy department.

Activities:
Activity: Placement
Related graduate capabilities and elements:
Discipline-specific GCs (Discipline-specific GCs)
Ethical Awareness (Ethical Awareness)
Writing (Writing)

Subject options

Select to view your study options…

Start date between: and    Key dates

Bendigo, 2015, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorDavid Morton

Class requirements

Tutorial Week: 10 - 22
Sixteen 1.0 hours tutorial per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Practical Week: 10 - 22
Six 3.0 hours practical per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"18 hours (total) laboratory work per semester"

Placement - Off Site
One 5.0 days placement - off site per study period on weekdays during the day and delivered via face-to-face.
"one 1-week placement (during the mid year break or in November)."

Lecture Week: 10 - 22
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
3-hour examination60 02, 01, 03, 05, 04
Calculation competency testHurdle requirement10 04
In-class practical testHurdle requirement25 03, 01
Placement taskHurdle requirment5 06

Malaysia, 2015, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorDavid Morton

Class requirements

Lecture Week: 10 - 22
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Placement - Off Site
One 5.0 days placement - off site per study period on weekdays during the day and delivered via face-to-face.
"one 1-week placement (during the mid year break or in November)."

Practical Week: 10 - 22
Six 3.0 hours practical per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
"18 hours (total) laboratory work per semester"

Tutorial Week: 10 - 22
Sixteen 3.0 hours tutorial per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
3-hour examination60 02, 01, 03, 05, 04
Calculation competency testHurdle requirement10 04
In-class practical testHurdle requirement25 03, 01
Placement taskHurdle requirment5 06

Malaysia, 2015, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorChristina Dennis

Class requirements

Tutorial Week: 31 - 43
Sixteen 1.0 hours tutorial per study period on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Practical Week: 31 - 43
Six 3.0 hours practical per study period on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"18 hours (total) laboratory work per semester"

Placement - Off Site
One 5.0 days placement - off site per study period on weekdays during the day and delivered via face-to-face.
"one 1-week placement (during the mid year break or in November)."

Lecture Week: 31 - 43
Two 1.0 hours lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Assessments

Assessment elementComments% ILO*
3-hour examination60 02, 01, 03, 05, 04
Calculation competency testHurdle requirement10 04
In-class practical testHurdle requirement25 03, 01
Placement taskHurdle requirment5 06