Molecular Design

The Molecular Design theme uses molecules to solve real world problems across a broad range of disciplines.

Researchers have diverse interests ranging from computational studies on the interaction of drugs with proteins, to molecular synthesis, and surface and material science.

Current projects include the design of new metal-based radiopharmaceuticals; synthesis of drugs targeting resistant strains of malaria and hospital born "superbacteria"; generation of anti-microbial surfaces using peptides; small molecule platelet inhibitors; and the design of metal catalysts to form difficult bonds, such as the C-F bond found in many pharmaceuticals.

Members have expertise in NMR spectroscopy, X-ray crystallography, mass spectrometry, chemical separations, computational analysis of systems (ranging from species as large as proteins to as small as a single proton) and analysis of surfaces using advanced techniques such as atomic force microscopy.