Publications

Lab leader

Miles MA, Kitevska-Ilioski T and Hawkins CJ (2017) Old and novel functions of caspase-2, Int Rev Cell Mol Biol., 332: 155-212.

Miles MA, Shekhar TM, Hall NE and Hawkins CJ (2016) TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells, Mutat Res 787: 15-31.

Caria S, Marshall B, Burton RL, Campbell S, Pantaki-Eimany D, Hawkins CJ, Barry M and Kvansakul M (2016) The N-terminus of the vaccinia virus protein F1L is an intrinsically unstructured region that is not involved in apoptosis regulation, J Biol Chem., 291(28): 14600-08.

Shekhar TM, Miles MA, Gupte A, Taylor S, Tascone B, Walkley CR and Hawkins CJ (2016) IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα, Oncotarget, 7(23): 33866-86.

Bloomer DT, Kitevska T, Brand IL, Jabbour AM, Nguyen H and Hawkins CJ (2016) Modeling metazoan apoptotic pathways in yeast, Methods Mol Biol., 1419: 161-83.

Green MM, Shekhar TM and Hawkins CJ (2016) Data on the DNA damaging and mutagenic potential of the BH3-mimetics ABT-263/Navitoclax and TW-37, Data Brief., 6: 710-14.

Shekhar TS, Green MM, Rayner DM, Miles MA, Cutts SM and Hawkins CJ (2015) Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells, Mutation Res., 777: 23-32.

Kitevska T, Roberts SJ, Pantaki-Eimany D, Boyd SE, Scott FL and Hawkins CJ (2014) Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate, Biosci Rep., 34(2): e00100.

Gangoda L, Doerflinger M, Srivastava R, Narayan N, Edgington LE, Orian J, Hawkins CJ, O'Reilly LA, Gu H, Bogyo M, Ekert P, Strasser A and Puthalakath H (2014) Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice, Cell Death Differ., 21: 1815-24.

Huang N, Civciristov S, Hawkins CJ and Clem RJ (2013) SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda, Insect Biochem Mol Biol., 43: 444-54.

Beaumont TE, Shekhar TM, Kaur L, Pantaki-Eimany D, Kvansakul M and Hawkins CJ (2013) Yeast techniques for modeling drugs targeting Bcl-2 and caspase family members, Cell Death Dis., 4: e619.

Brand IL, Civciristov S, Taylor NL, Talbo GH, Pantaki-Eimany D, Levina V, Clem RJ, Perugini MA, Kvansakul M and Hawkins CJ (2012) Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria, PLoS One, 7: e39248.

Brand IL, Green MM, Civciristov S, Pantaki-Eimany D, George C, Gort TR, Huang N, Clem RJ and Hawkins CJ (2011) Functional and biochemical characterization of the baculovirus caspase inhibitor MaviP35, Cell Death Dis., 2: e242.