Members

Theme Leaders

E Lee - Cell death and survival pathways

Our group examines the molecular mechanisms underlying cell fate decisions dictated by the processes of apoptosis and autophagy.

Mielke -  Mucosal Immunity and Cancer

Our group aims to understand the function of immune cells in maintaining homeostasis and cancer progression of the large bowel and stomach.


Members

Fairlie - Apoptosis, autophagy, cancer, drug development and peptides

Our group use a combination of biochemistry, cell biology, structural biology and medicinal chemistry approaches to understand the precise molecular mechanisms that control apoptosis.


Greening - Extracellular vesicles, exosomes, cancer biology and uterine biology

Our group uses an integrated system biology approach to understand extracellular communication in the context of the tumour microenvironment and uterine development.


Humbert - Cancer biology, cell polarity and tissue architecture

Our laboratory is interested in how cell asymmetry and tissue organisation can regulate cancer initiation, progression and metastasis.


Mathivanan - Exosomes, secretome and systems biology

Our group explores the role of extracellular matrix components (soluble secreted proteins and extracellular vesicles) in cancer and intercellular communication.


Nedev - Cancer cell biology, Extracellular vescles, Immunology, Flow cytometry, Fluorescent imaging, Proteomics

Our lab seeks to identify novel mechanisms regulating the biogenesis of extracellular vesicles (EVs) through our collaboration with the Research Centre for Extracellular Vesicles (RCEV).


Simpson - Cancer secretome, extracellular communication, exosome and extracellular vesicle biology

Our group utilizes an integrated proteomic/genomic strategy to understand the role of the extracellular environment in cancer progression.


Whelan - Biophysics, DNA damage, fluorescence, single molecule imaging

Our group develops and applies advanced fluorescence imaging techniques to visualize cells at the single molecule and nano-scale. In particular, we are working to understand DNA damage and repair.