Whelan - Biophysics, DNA damage, fluorescence, single molecule imaging

Group leader

Dr Donna Whelan

Research Fellow, College of Science, Health and Engineering

View profile, publications and contact details

Research overview

We specialize in applying state-of-the-art techniques to biological questions. In particular we make use of microscopic and spectroscopic methods to visualize the compositions and ultrastructures of individual cells and their subcomponents. These experiments offer a unique approach to probing crucial cellular pathways, the disease mechanisms that perturb them, and potential future treatments. Specifically, single molecule fluorescence techniques including super resolution imaging and Forster resonance energy transfer are used in tandem with infrared spectroscopic approaches to probe DNA damage response, DNA double strand break repair, viral perturbation of host cell structures, and the role of DNA damage in neurodegenerative disorders.

Research areas