Publications

For a complete list of publications see:
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Cully TR, Choi R, Bjorksten A, Stephenson DG, Murphy RM and Launikonis BS (2018) Junctional membrane Ca2+-dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutation, PNAS, doi: 10.1073/pnas.1800490115.

Xu H, Ren X, Lamb GD and Murphy RM (2018) Physiological and biochemical characteristics of skeletal muscles in sedentary and active rats, J Muscle Res Cell Motility, doi: 10.1007/s10974-018-9493-0.

Thomassen M, Hostrup M, Murphy RM, Cromer BA, Skovgaard C, Gunnarsson TP, Møller Christensen P and Bangsbo J (2018) Abundance of ClC-1 chloride channel in human skeletal muscle: Fibre type specific differences and effect of training, J Appl Physiol, doi: 10.1152/japplphysiol.01042.2017.

Christiansen D, Bishop DJ,  Broatch JR, Bangsbo J, McKenna MJ and Murphy RM (2018) Cold-water immersion after training sessions: Effects on fiber type-specific adaptations in muscle K+ transport proteins to sprint-interval training in men, J Appl Physiol,  doi: 10.1152/japplphysiol.00259.2018.

Barker RG, Xu H, Wyckelsma VL and Murphy RM (2018) Mitochondrial content is preserved throughout disease progression in the mdx mouse model of Duchenne muscular dystrophy, regardless of taurine supplementation, Am J Physiol Cell Physiol, doi.org/10.1152/ajpcell.00046.2017.

Barker RG, Frankish BP, Xu H and Murphy RM (2018) Elevated GLUT4 and glycogenin protein abundance correspond to increased glycogen content in the soleus muscle of mdx mice with no benefit associated with taurine supplementation, Physiol Reports, 6(5), doi: 10.14814/phy2.13596.

Christiansen D, Murphy RM, Broatch JR, Bangsbo J, McKenna MJ and Bishop DJ (2018) Increased FXYD1 and PGC-1α mRNA after blood flow-restricted running is related to fibre type-specific AMPK signalling and oxidative stress in human muscle, Acta Physiol, 223(2): e13045, doi: 10.1111/apha.13045.

CR Lamboley, H Xu, TL Dutka, ED Hanson, A Hayes, JA Violet, RM Murphy and GD Lamb (2018) Effect of androgen deprivation therapy on the contractile properties of type I and type II skeletal muscle fibres in men with non-metastatic prostate cancer, Clinical and Experimental Physiology and Pharmacology, 45(2): 146-154.

Barker RG, van der Poel C, Horvath D and Murphy RM (2017) Benefits of pre-natal taurine supplementation in preventing the onset of acute damage in the mdx mouse, PLoS Curr., doi: 10.1371/currents.md.9a3e357a0154d01050b591601cbd4fdb.

Wette SG, Smith HK, Lamb GD and Murphy RM (2017) Characterization of Muscle Ankyrin Repeat Proteins in human skeletal muscle, Am J Physiol Cell Physiol, 313(3): C327-339.

Diermeier S, Buttgereit A, Schuermann S, Winter L, Xu H, Murphy RM, Clemen CS, Schröder R and Friedrich O (2017) Pre-aged remodelling of myofibrillar cytoarchitecture in skeletal muscle expressing R349P mutant desmin, Neurobiology of Aging, 58(C): 77-87, doi: 10.1016/j.neurobiolaging.2017.06.001.

Wyckelsma VL, Levinger I, Murphy RM, Petersen AC, Perry BD, Hedges CP, Anderson MJ and McKenna MJ (2017) Intense interval training in healthy older adults increases skeletal muscle [3H]ouabain binding and also Na+,K+-ATPase α2 isoform abundance in Type II fibers, Physiol Rep., 5(7): e13219.

Wyckelsma VL, Levinger I, McKenna MJ, Formosa L, Ryan MT, Petersen AC and Murphy RM (2017) Preservation of skeletal muscle mitochondrial content in older adults: a relationship between mitochondrial dynamics, fibre type and exercise training, J Physiol, 595(11): 3345-3359.

Dutka TL, Mollica JP, Lamboley C, Weerakkody VC, Greening D, Posterino GS, Murphy RM and Lamb GD (2017) S-Nitrosylation and S-Glutathionylation of Cys134 on troponin I have opposing competitive actions on Ca2+ sensitivity in rat fast-twitch muscle fibers, Am J Physiol Cell Physiol, 312(3): C316-327.

Cully TR, Murphy RM, Roberts L, Raastad T, Fasse R, Coombes JS, Jayasinghe ID and Launikonis BS (2017) The plasmalemma of human skeletal muscle alters its structure to change its Ca2+ handling in response to heavy load resistance exercise, Nature Communications, 8: 14266.

MacInnis MJ, Zacharewicz E, Haikalis ME, Martin BJ, Skelly LE, Tarnopolsky MA, Murphy RM* and Gibala MJ* (2017) Superior mitochondrial adaptations in human skeletal muscle after interval compared to continuous single-leg cycling matched for total work, J Physiol., 595(9): 2955-2968.

Xu H, Lamb GD and Murphy RM (2017) Changes in contractile and metabolic parameters of skeletal muscle as rats age from 3 to 12 months, J Muscle Cell Res Motility, doi: 10.1007/s10974-017-9484-6.

Goodman C, Coenen A, Frey J, You J, Barker RG, Frankish BP, Murphy RM and Hornberger T (2017) Insights into the role and regulation of TCTP in skeletal muscle, Oncotarget, 8(12): 18754-18772, doi: 10.18632/ oncotarget.13009.

Gilbert DF, Stebbing M, Künzel1 K, Murphy RM, Zacharewicz E, Buttgereit A, Stokes L, Adams DJ and Friedrich O (2016) Store-operated Ca2+ entry (SOCE) and purinergic receptor-mediated Ca2+ homeostasis in murine BV2 microglia cells: early cellular responses to ATP-mediated microglia activation, Front Mol Neuro., 9: 111.

Perry BD, Wyckelsma VL, Murphy RM, Steward C, Anderson M, Levinger I, Petersen AC and McKenna MJ (2016) Dissociation between short-term unloading and resistance training effects on skeletal muscle Na+-K+-ATPase, muscle function and fatigue in humans, J Appl Physiol., 121: 1074-86.

Horvath DM, Murphy RM, Mollica JP, Hayes A and Goodman C (2016) The effect of taurine and β-alanine supplementation on taurine transporter protein and fatigue resistance in skeletal muscle from mdx mice, Amino Acids, 48: 2635-45.

Mohktar RA, Montgomery MK, Murphy RM and Watt MJ (2016) Perilipin 5 is dispensable for normal substrate metabolism and in the adaptation of skeletal muscle to exercise training, Am J Physiol Endo Met., 311: E128-37.

Xu H, Frankenberg NT, Lamb GD, Gooley PR, Stapleton DI and Murphy RM (2016) When phosphorylated at Thr148, the β2 subunit of AMP activated kinase does not associate with glycogen in skeletal muscle, Am J Physiol Cell Physiol., 311: C35-42.

Wyckelsma VL, McKenna MJ, Levinger I, Petersen AC, Lamboley CR and Murphy RM (2016) Cell specific changes in the abundance of GAPDH and Na+, K+-ATPase proteins in skeletal muscle from aged individuals, implications for protein measurements, Exp Gerontol., 75: 8-15.

Cully TR, Edwards JN, Murphy RM and Launikonis BS (2016) A quantitative description of tubular system Ca2+-handling in fast- and slow-twitch muscle fibres, J Physiol., 594: 2795-810.

Lamboley CR, Wyckelsma VL, McKenna MJ, Murphy RM and Lamb GD (2016) Ca2+ leakage out of the sarcoplasmic reticulum is increased in type I skeletal muscle fibres in aged humans, J Physiol., 594: 469-81.

Harvey TJ, Murphy RM, Morrison J and Posterino GS (2015) Maternal nutrient restriction alters Ca2+ handling and contractile function of isolated left ventricle bundles in male but not female juvenile rats, PLoS One, 10(9): e0138388.

Lamboley CR, Wyckelsma VL, Dutka TL, McKenna MJ, Murphy RM and Lamb GD (2015) Contractile properties and sarcoplasmic reticulum calcium content in type I and type II skeletal muscle fibres in active aged humans, J Physiol., 593(11): 2499-514.

Xu H, Stapleton D and Murphy RM (2015) Rat skeletal muscle glycogen degradation pathways reveal differential association of glycogen related proteins with glycogen granules, J Biochem Physiol., 71(2): 267-80.

Murphy RM (2015) Clarity for AMPK – dissecting out human skeletal muscle responses to exercise, J Physiol., 593(8): 1769-70.

Wyckelsma VL, McKenna MJ, Serpiello FR, Lamboley CR, Aughey RJ, Stepto NK, Bishop DJ and Murphy RM (2015) Single fiber expression and fiber-specific adaptability to short-term intense exercise training of Na+,K+-ATPase α and β isoforms in human skeletal muscle, J Appl Physiol., 118(6): 699-706.

Hong YH, Frugier T, Zhang M, Murphy RM, Lynch GS, Betik AC, Rattigan S and McConell GK (2015) Glucose uptake during contraction in isolated skeletal muscle of neuronal nitric oxide synthase mu knockout mice, J Appl Physiol., 118(9): 1113-21.

Pompeani N, Rybalka E, Stathis CG, Latchman H, Murphy RM, Croft K and Hayes A (2015) Skeletal muscle atrophy in Zucker obese rats occurs independently of calpain activation or ROS-mediated lipase activity, J Negative Results, 13: 153.

Head SI, Chan S, Houweling P, Quinlan KGR, Murphy RM, Wagner S, Friedrich O and North KN (2014) Altered Ca2+ kinetics associated with α-Actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution, PLoS Genet., 11(2): e1004862.

Kuruppath S, Sharp JA, Lefevre C, Murphy RM and Nicholas KR (2014) Comparative analysis of caveolins in mouse and tammar wallaby: Role in regulating mammary gland function, Gene, 552(1): 51-58.

Lamboley C, Murphy RM, McKenna M and Lamb GD (2014) Sarcoplasmic reticulum Ca2+ uptake and leak properties and SERCA protein expression in type I and type II fibres of human skeletal muscle, J Physiol., 592(6): 1381-95.

Frankenberg NT, Lamb GD, Overgaard K, Murphy RM and Vissing K (2014) Small heat shock proteins translocate to the cytoskeleton in human skeletal muscle following eccentric exercise independently of phosphorylation, J Appl Physiol., 116(11): 1463-72.

Frankenberg NT, Lamb GD, Vissing K and Murphy RM (2014) Subcellular fractionation reveals HSP72 does not associate with SERCA in human skeletal muscle following damaging eccentric and concentric exercise, J Appl Physiol., 116(11): 1503-11.

Dutka TL, Lamboley CR, Murphy RM and Lamb GD (2014) Acute effects of taurine on sarcoplasmic reticulum Ca2+ accumulation and contractility in human type I and type II skeletal muscle fibers, J Appl Physiol., 117(7): 797-805.

Murphy RM and Lamb GD (2013) Important considerations for protein analyses using antibody based techniques: down-sizing western blotting up-sizes outcomes, J Physiol., 591(23): 5823-31.

Lamboley C, Murphy RM, McKenna M and Lamb GD (2013) Endogenous and maximal sarcoplasmic reticulum calcium content and calsequestrin expression in Type I and Type II human skeletal muscle fibres, J Physiol., 591(23): 6053-68.

Fajardo VA, McMeekin L, Basic A, Lamb GD, Murphy RM and LeBlanc PJ (2013) Isolation of sarcolemmal plasma membranes by mechanically skinning rat skeletal muscle fibers for phospholipid analysis, Lipids, 48(4): 421-30.

Murphy RM, Dutka TL, Horvath D, Bell JR, Delbridge LM and Lamb GD (2013) Ca2+-dependent proteolysis of junctophilin 1 and junctophilin 2 in skeletal and cardiac muscle JP in muscle weakness, J Physiol Rapid Report, 591(3): 719-29.

Thomassen M, Murphy RM and Bangsbo J (2013) Fibre type specific changes in FXYD1 phosphorylation during acute intense exercise in humans, J Physiol Rapid Report, 591(6): 1523-33.

Cully TR, Edwards JN, Friedrich O, Stephenson DG, Murphy RM and Launikonis BS (2012) Changes in plasma membrane CaATPase (PMCA) and stromal interacting molecule 1 (STIM1) expression levels for Ca2+ signalling in dystrophic mdx mouse muscle, Am J Physiol Cell Physiol., 303(5): C567-76.

Larkins NT, Murphy RM and Lamb GD (2012) Influences of temperature, oxidative stress and phosphorylation on binding of heat shock proteins in skeletal muscle fibers, Am J Physiol Cell Physiol., 303(6): C654-65.

Murphy RM, Xu H, Latchman H, Larkins NT, Gooley PR and Stapleton D (2012) Single fiber analyses of glycogen related proteins reveal their differential association with glycogen in rat skeletal muscle, Am J Physiol Cell Physiol., 303(11): C1146-55.

Mollica JP, Dutka TL, Merry TL, Lamboley CR, McConell GK, McKenna MJ, Murphy RM and Lamb GD (2012) S-glutathionylation of Troponin I (fast) increases contractile apparatus Ca2+-sensitivity in fast-twitch muscle fibres in rats and humans, J Physiol., 590(6): 1443-63.

Dutka TL, Lamboley CR, McKenna MJ, Murphy RM and Lamb GD (2012) Effects of carnosine on contractile apparatus Ca2+-sensitivity and sarcoplasmic reticulum Ca2+ release in human skeletal muscle fibers, J Appl Physiol., 112(5): 728-36.

Larkins NT, Murphy RM and Lamb GD (2012) Absolute amounts and diffusibility of HSP72, HSP25 and αB-crystallin in fast- and slow-twitch skeletal muscle fibers of rat, Am J Physiol Cell Physiol., 302(1): C228-39.

* Equal senior authors