Members
Theme Leader
Heras - Bacterial virulence factors: structure and function
Our group studies the molecular mechanisms underlying Gram-negative bacterial infections to develop antibacterial drugs that are not susceptible to existing resistance mechanisms.
Members
Baxter - Cell death, efferocytosis, vascular biology, cardiovascular disease
Our group aims to understand how dying cells within the blood vessels communicate with surrounding tissue and to elucidate the importance of cell clearance by vascular cells, both in the context of normal vessel maintenance and to promote vessel repair following injury or disease.
Binger - Immunometabolism and macrophage biology
Our research aims to understand the link between what immune cells ‘eat’ in our tissues and how this is connected to their normal biology and inflammatory diseases such as high blood pressure and diabetes.
Cheng Sim (Hill) - Neurodegenerative diseases, extracellular vesicles and noncoding RNAs
Our group uses a combination of biochemistry, molecular and cell biology to investigate neurodegenerative diseases such as Alzheimer's, Prion and Parkinson's diseases.
Foley - Single domain antibodies in human disease
Our group uses single domain antibodies that have been developed from sharks to identify novel therapeutics against a number of chronic diseases.
Grant - Immune responses against pathogens
Dr Grant's research focuses on identifying and characterising immune cell responses towards different pathogens, with a particular emphasis on influenza virus, which kills more than half a million people worldwide annually.
Gras – Viral and structural immunology
Our laboratory is focused on understanding how to combat viral infections.
Hulett - Inflammation and tumour progression
Our group studies the molecular basis of tumour progression and inflammatory disease to develop novel anti-cancer and anti-inflammatory drugs.
Irving - Inflammation
Our group studies the molecular interactions in signal transduction networks regulating inflammation.
Johnson - Mechanisms of cell signalling regulation, treatments for rare genetic disorders
Our group investigates the complex interplay between cells and their environment to better understand the molecular processes that underpin animal development and health.
Keightley - Myeloid development and disease
Our group uses zebrafish models to discover and understand molecular pathways in blood cell development and disease.
Kettle - Autonomic and central nervous system regulation of metabolism
Our group examines the neurobiology and neurochemistry that underlies the physiology of metabolism.
Kha Phan - Cell death, dead cell clearance and infection
Our group aims to advance current understanding of the dynamic host-pathogen interaction along apoptosis–efferocytosis axis and to develop novel therapeutics for respiratory infections, the leading pathogenic causes of global morbidity and mortality.
Kvansakul - Structural biology of cell death and host-pathogen interactions
Our group examines how viruses hijack cellular defence systems to ensure their own proliferation and survival.
Okuda - Vascular Biology, Drug Discovery, Regeneration, Zebrafish research
Our group uses the optically transparent zebrafish model to identify and characterise vascular modulatory therapeutics.
Orian - Neurodegenerative diseases
Our group uses proof-of-concept to identify pathological and molecular mechanisms of disease. We also evaluate candidate MS drugs.
Poon - Apoptotic cell disassembly and clearance
Our group studies the machinery that control how dying cells can disassemble into smaller pieces, and the importance of cell disassembly in disease settings, to identify new drugs to control this process.
Puthalakath - Regulation of apoptosis by Bcl-2 family proteins
Our group researches the molecular basis of apoptosis regulation during heart failure, sepsis and in chemo resistance.
Tucci - Bacteriophage as alternatives to antibiotics, pharmacogenomics and pharmacy practice
Our group studies the use of bacteriophage as alternatives to antibiotics. We also examine the personalization of medicine to fit a patient's genetic profile, and patient management of medication in the treatment of chronic disease.
Van Dyke - Applied animal physiology
Our group studies animal models to discover novel mechanisms underlying reproductive, developmental, and immune functions.
Wijeyewickrema - Proteases, inhibitors and receptors: relationship to disease states
Our group researches enzymes, called proteases, which operate at the interface between a host, such as a human being and microbes that cause disease.