Characterising cell death
Dr Amy Baxter, Dr Ivan Poon and collaborators have defined the characteristics of apoptotic bodies for the first time. Their findings, published in the Journal of Extracellular Vesicles, will lead to better characterisation of these cell particles in future studies.
Understanding nerve loss in multiple sclerosis
PhD candidate Pece Kocovski, Dr Matthew Hale, Dr Jacqueline Orian and collaborators have demonstrated that platelets can interact with neurons. This may play a critical role in nerve loss in multiple sclerosis. Their findings, published in the Journal of Clinical Medicine, may lead to new therapeutic targets for multiple sclerosis.
Identifying the key to antibiotic resistance
Bacteria are becoming increasingly resistant to antibiotics. This is particularly the case for drug-resistant Neisseria gonorrhoeae. Dr Begoña Heras’ group and collaborators have identified a key protein that is required for the survival of Neisseria pathogens. Their findings, published in the Journal of Biological Chemistry, may lead to a new generation of anti-neiserial drugs.
Genetic basis of HIV/AIDS medication side effects
Dr Joseph Tucci and collaborators have discovered that people from Papua New Guinea carry higher rates of specific genetic polymorphisms which predispose them to potentially life threatening side effects from HIV/AIDS medications. Their findings, published in Pharmacogenetics & Genomics, may lead to personalisation of HIV/AIDS medication regimes.