Infection and Immunity

Infectious diseases are among the greatest global health challenges as shown by recent and past pandemics.

Human activities, including urban expansion, intensive farming, and increased global travel, have accelerated the emergence and spread of new infectious diseases. At the same time the growing problem of antimicrobial resistance, is making once-reliable treatments less effective.

Research at LIMS focuses on advancing our understanding of infection processes, improving early detection and monitoring of infections. With the goal of developing novel methods for their prevention and treatment, all with a personalised medicine and health equity lens. Infection and Immunity research explores how the body responds to infections and immune system disorders, with the goal of fine-tuning these responses to improve health.

By understanding the immune mechanisms that drive diseases such as cancer, diabetes, and cardiovascular conditions. LIMS researchers aim to develop targeted therapies that restore balance and prevent harmful inflammation. LIMS is at the forefront of discovering how immune modulation can transform treatment across a wide range of chronic and infectious diseases.

Members

Program leads

Begoña Heras group

Begoña Heras group

Structural biology and bacterial pathogenesis

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Ashley Mansell group

Ashley Mansell group

Innate immunity, PRRs and inflammation

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Program members

Adam Mechler group

Nanochemistry, self-assembling nanosystems, biomembranes, antimicrobial peptides

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Amy Baxter group

Dying cell communication and clearance

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Antony Vinh group

Hypertension and Immunobiology

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Cathryn Hogarth group

Vitamin A regulation of male reproduction

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Dimitra Chatzileontiadou group

Anti-viral immunity: understanding the immune system actions when facing viral infections

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Ebony Monson group

Lipid biology, immune response, viruses, antiviral therapies

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Ella Johnson group

Novel EV-based therapies

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Emma Grant group

Emma Grant group

Immune responses against pathogens

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Helen Irving group

Inflammation

Helena Kim group

Stroke and Brain Inflammation

Ibrahim Javed group

Ivan Poon group

Ivan Poon group

Apoptotic cell disassembly and clearance

Jason Dutton group

Inventing new chemistry

Karla Helbig group

Antiviral Innate Immunity

Kha Phan group

Kha Phan group

Cell death, dead cell clearance and infection

Sarah Annesley group

Molecular Cell Biology

Seb Dworkin group

Developmental Genetics

Shannon Hedtke group

Shannon Hedtke group

Accelerating elimination of parasite diseases

Stephanie Gras group

Stephanie Gras group

Viral and structural immunology

Travis Johnson group

Travis Johnson group

Mechanisms of cell signaling regulation, treatments for rare genetic disorders

Travis Beddoe group

Travis Beddoe group

Agriculture Bio-Solutions

Vivian Tran group

Wenyi Li group

Wenyi Li group

Chemical Biology, Peptide Chemistry