Parasitology

Brockwell, Y.M., SPITHILL, T.W., Anderson, G.R., Grillo, V. and Sangster,N.C. Comparative kinetics of coproantigen and serological ELISA and faecal egg count in cattle experimentally infected with Fasciola hepatica and following treatment with Triclabendazole. Vet Parasitology (in press) (2013)

Norbury LJ, Hung A, Beckham S, Pike RN, SPITHILL TW, Craik CS, Choe Y, Fecondo JV, Smooker PM. Analysis of Fasciola cathepsin L5 by S(2) subsite substitutions and determination of the P(1)-P(4) specificity reveals an unusual preference. Biochimie. 94: 1119-1127 (2012).

Jayaraj R, Piedrafita D, Spithill T, Smooker P. Evaluation of the immune responses induced by four targeted DNA vaccines encoding the juvenile liver fluke antigen, cathepsin B in a mouse model. Genet Vaccines Ther. 10: 7 (2012).

R .A. Wilson., J. M. Wright., W.de Castro Borges., S J. Parker-Manuel., A.A. Dowle., P. D. Ashton., N. D. Young., R.B. Gasser and T.W. SPITHILL. Exploring the Fasciola hepatica tegument proteome. Int J Parasitology 41:1347-59 (2011).

Young, N.D., Jex, A.R., Cantacessi, C., Hall, R.,Campbell, B.E., Tangkawatana, S., Laha, T., SPITHILL, T.W., Gasser, R.B. A portrait of the transcriptome of the neglected trematode, Fasciola gigantica - biological and biotechnological implications. PLoS NTD PLoS NTD 5(2): e1004 (2011).

Norbury, L.J., Beckham, .S, Pike, R.N., Grams, R., SPITHILL, T.W., Fecondo, J.V., Smooker, P.M. Adult and juvenile Fasciola cathepsin L proteases: Different enzymes for different roles. Biochimie. 93: 604-11 (2011). 

Ndao, M., Rainczuk, A., Rioux, M-C., SPITHILL, T.W., Ward, B.J. Is SELDI-TOF a valid tool for diagnostic biomarkers? Trends in Parasitology 26:561-567 ( 2010).

Smooker, P.M., Jayaraj, R., Pike, R.N., SPITHILL, T.W. Cathepsin B proteases of flukes – the key to facilitating parasite control? Trends in Parasitology 26:506-514 (2010).

Piedrafita, D., SPITHILL, T.W., Smith, R.E., Raadsma, H.W. Improving animal and human health through understanding liver fluke immunology. Parasite Immunology 32:572-581 (2010).

Ndao, M., SPITHILL, T.W., Caffrey, R., Li, H., Podust, V.N., Perichon, R., Santamaria, C., Ache, A., Duncan, M., Powell, M.R., Ward, B.J. Identification of novel diagnostic serum biomarkers for Chagas' disease in asymptomatic subjects by mass spectrometric profiling. J Clin Microbiol. 48:1139-49 (2010).

Purcell, L.A., Leitao, R., Ono, T., Yanow,S.K., Pradel, G., SPITHILL, T.W., Rodriguez, A. A putative kinase related protein (PKRP) from Plasmodium berghei mediates infection in the midgut and salivary glands of the mosquito. Int J Parasitol. 40: 979-988 (2010).

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