Dr Annesley, from the School of Agriculture, Biomedicine and Environment, will investigate whether molecules that regulate gene expression and energy production, known as microRNAs, are dysregulated in post-viral CFS.
The study will focus on platelets which, beyond their role in blood clotting, are increasingly recognised as key regulators of immune function.
“This funding marks an exciting step forward in our efforts to understand the complex biology of CFS,” Dr Sarah Annesley said.
“We predict that abnormal platelet activation may contribute to immune system dysfunction in CFS, and this pilot study will help us explore that possibility.”
“Importantly, our research is co-designed with individuals who have lived experience of CFS, ensuring it remains grounded in the realities of those affected.”
Working with Dr Annesley are Dr Daniel Missailidis, Dr Jacqueline Orian, Dr Nina Riddell, Dr Lesley Cheng and Dr Melanie Murphy.
La Trobe Deputy Vice-Chancellor Research and Innovation Professor Chris Pakes welcomed the outcome.
“This support from ME Research UK reflects the calibre of research being conducted at La Trobe and our commitment to tackling complex health challenges,” Professor Pakes said.
“This condition affects millions globally, and we are proud to contribute to the search for better diagnostics and treatments.”
The research aims to uncover potential biomarkers and deepen scientific understanding of CFS’s underlying mechanisms, paving the way for future therapeutic advances.
In 2023, Dr Annesley was a recipient of La Trobe’s Tracey Banivanua Mar Fellowship.
