Cardiovascular Biology

Cardiovascular biology is at the forefront of biomedical innovation, integrating molecular science, physiology and translational research to tackle one of Australia’s biggest health challenges.

Research focus

This program is at the intersection of biology, clinical relevance and community impact aiming to unravel the complexities of cardiovascular disease. With a strong foundation in experimental models and cutting-edge technologies, the program is committed to reducing the burden of cardiovascular disease through scientific excellence, education and community engagement.

Through this research program, we aim to translate fundamental discoveries into real-world solutions for cardiovascular health. The program spans multiple research sectors and centres, each targeting a key aspect of cardiovascular disease, from molecular proteomics and vascular therapeutics to immune mechanisms and metabolic disorders. Together with clinical partners, industry and local communities, we ensure that the program’s research is impactful and inclusive.

Advanced models such as organoids, zebrafish, and stem cell systems are used to explore disease mechanisms and test novel therapies. The program also leverages multi-omics technologies and extracellular vesicle biology to develop next-generation diagnostics and therapies. By integrating molecular insights with translational strategies, the cardiovascular biology program is driving innovation in prevention, diagnosis and treatment of cardiovascular disease.

Members

Program leads

Grant Drummond group

Chris Sobey group

Program members

David Greening group

David Greening group

Our laboratory is focused on understanding the molecular function of nano-sized biological extracellular vesicles.

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Amy Baxter group

Amy Baxter group

Our group aims to understand how dying cells within the blood vessels communicate with surrounding tissue and to elucidate the importance of cell clearance

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Kazuhide Shaun Okuda group

Kazuhide Shaun Okuda group

Dr Okuda's research uses the zebrafish model to identify vascular modulatory therapeutic targets/leads for treating these diseases.

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