COMPARE Research Trial Results released

Constraint Induced Aphasia Therapy or Multi-Modality Aphasia Therapy: which is better and for whom?
Results of the COMPARE RCT investigating CIAT Plus, M-MAT and usual care in people with chronic post-stroke aphasia.

Professor Miranda Rose together with the team at the Aphasia CRE are pleased to announce that the main results of the COMPARE research trial have been published in the Journal of Neurology, Neurosurgery and Psychiatry. The link to the publication is here

We have created aphasia friendly information about the trial:

We have been busy disseminating the results virtually at conferences around the world: to date we have presented the results at USA Clinical Aphasiology Conference, the British Aphasiology Conference, Japan Speech and Language Therapy conference, German Aphasia Congress, Brazilian Speech Therapy Conference, Philippines Speech Therapy conference, SMART Strokes (Australia), and in a seminar for the Aphasia CRE series. In 2022, we aim to present further results at the Australian Society for the Study of Brain Injury conference, the Stroke Society of Australasia and Speech Pathology Australia national conference.

Our researchers at the Aphasia CRE are continuing to mine the COMPARE data set to examine: patient predictors of treatment response; ratings of fatigue and distress during the trial; deeper analyses of the discourse date; economic analysis of treatment costs; and comparisons of the results from the intense (main trial) versus distributed (sub-study) doses. Dr John Pierce has been funded to develop a telehealth version of M-MAT and we continue to seek funding to investigate the effects of different doses and maintenance doses of the interventions.

We would like to thank our large team and all participants that contributed to this important trial.

Click here to view Prof Miranda Rose Seminar of the COMPARE trial results

Please direct any questions or feedback to or Phone: (03) 9479 2088