PHARMACY PRACTICE AND THERAPEUTICS B (METABOLIC AND ENDOCRINE)

PHA3THB

2021

Credit points: 15

Subject outline

This subject will integrate the teaching of pharmacology, medicinal chemistry and pharmacy practice relating to the use of drugs for gastroenterology, hepatic, reproductive and endocrine disorders. You will initially explore the mechanism of action of these drugs, specifically how they affect biochemical and physiological processes at the cellular and organ level, and then relate this to the overall clinical effect on the individual. The medicinal chemistry of these drugs will then be explored so that structure-function relationships can be determined at the molecular level. Finally, the pharmacy practice issues relating to these conditions and medications will be addressed, in a manner that highlights how these drugs can ameliorate the various disease states and affect the overall clinical condition of the patient. . You will have the opportunity to explore and apply their knowledge in drug metabolism and drug interactions during a one-week, mid-year rural community pharmacy placement.

SchoolMolecular Sciences

Credit points15

Subject Co-ordinatorNick Standen

Available to Study Abroad/Exchange StudentsYes

Subject year levelYear Level 3 - UG

Available as ElectiveNo

Learning ActivitiesN/A

Capstone subjectNo

Subject particulars

Subject rules

Prerequisites PHA2THA and must be admitted into the Bachelor of Pharmacy course (SHPB)

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsPHA3PGC

Quota Management StrategyN/A

Quota-conditions or rulesN/A

Special conditionsN/A

Minimum credit point requirementN/A

Assumed knowledgeN/A

Learning resources

An Introduction to Medicinal Chemistry

Resource TypeBook

Resource RequirementRecommended

AuthorPatrick, G

Year2017

Edition/Volume6TH ED

PublisherOXFORD, NEW YORK

ISBN9780198749691

Chapter/article titleN/A

Chapter/issueN/A

URLhttps://global.oup.com/academic/product/an-introduction-to-medicinal-chemistry-9780198749691?cc=au&lang=en& 

Other descriptionN/A

Source locationN/A

Pharmacology

Resource TypeBook

Resource RequirementRecommended

AuthorRang HP, Dale MM, Ritter JM and Moore PK

Year2016

Edition/Volume8TH ED

PublisherElsevier 

ISBN9780702054976

Chapter/article titleN/A

Chapter/issueN/A

URLhttps://www.elsevier.com/books/rang-andampamp-dales-pharmacology/ritter/978-0-7020-5362-7 

Other descriptionN/A

Source locationN/A

Clinical Pharmacy and Therapeutics

Resource TypeBook

Resource RequirementRecommended

AuthorCate Whittlesea, Karen Hodson Eds

Year2018

Edition/Volume6TH ED

PublisherElsevier

ISBN9780702070129

Chapter/article titleN/A

Chapter/issueN/A

URLhttps://www.elsevier.com/books/clinical-pharmacy-and-therapeutics/whittlesea/978-0-7020-7012-9 

Other descriptionN/A

Source locationN/A

Therapeutic Guidelines: Gastrointestinal. Version 4

Resource TypeBook

Resource RequirementRecommended

AuthorTherapeutic Guidelines Ltd

Year2006

Edition/VolumeN/A

PublisherTHERAPEUTIC GUIDELINES LIMITED, MELBOURNE

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Therapeutic Guidelines: Endocrinology. Version 5

Resource TypeBook

Resource RequirementRecommended

AuthorTherapeutic Guidelines Ltd. Expert Writing Group

Year2011

Edition/VolumeN/A

PublisherTHERAPEUTIC GUIDELINES LTD, MELBOURNE.

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Goodman & Gilman's Manual of Pharmacology and Therapeutics

Resource TypeBook

Resource RequirementPrescribed

AuthorRanda Hilal-Dandan, Laurence L. Brunton

Year2013

Edition/Volumesoft cover portable volume 2ND ED

PublisherMCGRAW-HILL

ISBN9780071769174

Chapter/article titleN/A

Chapter/issueN/A

URLhttps://accesspharmacy.mhmedical.com/book.aspx?bookID=1810 

Other descriptionN/A

Source locationN/A

Career Ready

Career-focusedNo

Work-based learningYes

Self sourced or Uni sourced
Uni Sourced

Entire subject or partial subjectPartial subject

Total hours/days required40

Location of WBL activity (region)Domestic - regional

WBL addtional requirementsN/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Explain the pathophysiology for a selection of disease states associated with the endocrine system, reproductive system and body metabolism.
02. Relate the relevant class of drugs to activity at the molecular level, specifically, effect on relevant receptors and other regulatory molecules and processes.
03. Describe and explain the relationship between drug actions and therapeutic outcomes, specifically in the amelioration of disease states associated with the endocrine system or body metabolism.
04. Describe the absorption, elimination and metabolism of endocrine and gastrointestinal drugs and relate this to clinical practice and how pharmacogenetics affects this.
05. Anticipate and rationalize interaction between drugs including over-the-counter (OTC and other substances)
06. Critically assess drug use and disease states in a defined case study scenario against clinical guidelines.
07. Discuss alterations in human metabolism as a consequence of altered liver function.
08. Apply the Quality Use of Medicines (QUM) principles in the context of supply of over-the-counter (OTC) medication

Subject options

Select to view your study options…

Start date between: and    Key dates

Bendigo, 2021, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Subject Instance Co-ordinatorNick Standen

Class requirements

LectureWeek: 10 - 22
Three 1.00 hour lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

TutorialWeek: 13 - 22
Six 1.00 hour tutorial per study period on weekdays during the day from week 13 to week 22 and delivered via face-to-face.

WorkShopWeek: 11 - 22
One 2.00 hours workshop per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.

Assessments

Assessment elementCommentsCategoryContributionHurdle% ILO*

2 x case studies (1,500 words equiv. in total)

Feedback from cases is given within three weeks of submission. Feedback from the first case is returned before the submission of the second case.

N/AOtherIndividualNo40 SILO1, SILO2, SILO3, SILO6, SILO7

Clinical Critical evaluation task (1,300 words) 

Feedback is not returned for summative assessment.

N/AOtherIndividualNo50 SILO1, SILO2, SILO3, SILO4, SILO5, SILO6, SILO7

Mid-semester MCQ test (1 hour) (1000 words equiv)

N/AOtherIndividualNo10 SILO1, SILO2, SILO3, SILO4, SILO5, SILO6, SILO7

Oral exam 20 minutes (1000 words equivalent) 

Feedback is not returned for summative assessment.

N/AOral presentationIndividualNo20 SILO1, SILO2, SILO3, SILO4, SILO5, SILO6, SILO7

Mid-year placement hurdle requirement - satisfactory placement and manual completion. Completed placement rubric and preceptor comments are returned to students 

N/AOtherIndividualYes0 SILO8