PHARMACY PRACTICE AND THERAPEUTICS B (METABOLIC AND ENDOCRINE)
Credit points: 15
This subject will integrate the teaching of pharmacology, medicinal chemistry and pharmacy practice relating to the use of drugs for gastroenterology, hepatic, reproductive and endocrine disorders. Students will initially explore the mechanism of action of these drugs, specifically how they affect biochemical and physiological processes at the cellular and organ level, and then relate this to the overall clinical effect on the individual. The medicinal chemistry of these drugs will then be explored so that structure-function relationships can be determined at the molecular level. Finally, the pharmacy practice issues relating to these conditions and medications will be addressed, in a manner that highlights how these drugs can ameliorate the various disease states, and affect the overall clinical condition of the patient.
SchoolSchool of Molecular Sciences/LIMS
Subject Co-ordinatorRichard Summers
Available to Study Abroad StudentsYes
Subject year levelYear Level 3 - UG
Prerequisites PHA2THA and must be admitted into the Bachelor of Pharmacy course (SHPB).
Equivalent subjects PHA3PGC
|Resource Type||Title||Resource Requirement||Author and Year||Publisher|
|Readings||Goodman & Gilman's Manual of Pharmacology and Therapeutics (Soft cover portable volume)||Prescribed||Brunton, L, Knollman B, & Hilal-Dandan R eds. 2013||10TH ED MCGRAW-HILL|
|Readings||An Introduction to Medicinal Chemistry||Recommended||Patrick, G 2009||4TH ED, OXFORD, NEW YORK|
|Readings||Clinical Pharmacy and Therapeutics||Recommended||Walker R & Whittlesea C Eds 2011||5TH ED, EDINBURGH: CHURCHILL LIVINGSTONE|
|Readings||Pharmacology||Recommended||Rang HP, Dale MM, Ritter JM and Moore PK 2016||8TH ED CHURCHILL LIVINGSTONE, EDINBURGH|
|Readings||Therapeutic Guidelines: Endocrinology. Version 5||Recommended||Therapeutic Guidelines Ltd. Expert Writing Group 2011||THERAPEUTIC GUIDELINES LTD, MELBOURNE.|
|Readings||Therapeutic Guidelines: Gastrointestinal. Version 4||Recommended||Therapeutic Guidelines Ltd 2006||THERAPEUTIC GUIDELINES LIMITED, MELBOURNE|
Graduate capabilities & intended learning outcomes
01. Explain the pathophysiology for a selection of disease states associated with the endocrine system, reproductive system and body metabolism.
- The pathophysiology of endocrine and metabolic disease states is taught in lectures and reinforced in tutorial classes and workshops. Students apply and practice their knowledge of pathophysiology by working on case studies. Students demonstrate understanding of pathophysiology in the end-of-semester examination.
02. Relate the relevant class of drugs to activity at the molecular level, specifically, effect on relevant receptors and other regulatory molecules and processes.
- Appropriate pharmacy practice skills and judgement are taught in lectures and reinforced in tutorial classes and workshops. Students apply and practice their knowledge and skills by working on case studies during the semester and demonstrate their understanding in the end-of-semester examination.
03. Describe and explain the relationship between drug actions and therapeutic outcomes, specifically in the amelioration of disease states associated with the endocrine system or body metabolism.
- Students analyse case studies of patients with endocrine or metabolic disorders in workshops by applying their knowledge from pharmacology and pharmacy practice. Students demonstrate their understanding in the end-of-semester examination.
04. Describe the absorption, elimination and metabolism of endocrine and gastrointestinal drugs and relate this to clinical practice and how pharmacogenetics affects this.
- Therapeutic application of endocrine and gastrointestinal drugs are explained in lectures and reinforced in workshops.
05. Anticipate and rationalize interaction between drugs(including over-the-counter (OTC) and other substances)
- Drug interaction processes and their application in therapeutics including ethnic differences in human metabolism are explained in lectures and reinforced in workshops.
06. Follow guidelines to critically assess drug use and disease states in a defined case study scenario.
- Differences in human metabolism caused by altered body metabolism are taught in lectures and reinforced in tutorial classes and workshops. Students apply and practice their knowledge and skills by working on case studies during the semester and demonstrate their understanding in the end-of-semester examination.
07. Discuss alterations in human metabolism as a consequence of altered liver function.
- Case Study assignments are prepared for assessment. The aim is to integrate knowledge and skills from pharmacology, medicinal chemistry and pharmacy practice. Case studies are reinforced as questions in the final exam.
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Bendigo, 2018, Semester 1, Day
Maximum enrolment sizeN/A
Subject Instance Co-ordinatorRichard Summers
Three 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Six 1.0 hours tutorial per study period on weekdays during the day from week 13 to week 22 and delivered via face-to-face.
One 2.0 hours workshop per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.
|2 x case studies (1000 words equiv. in total)||40||01, 02, 03, 06, 07|
|One 2-hour examination||50||01, 02, 03, 04, 05, 06, 07|
|Mid-semester test (1 hour) (1000 words equiv)||10||01, 02, 03, 04, 05, 06, 07|