PHARMACOLOGY B

PHA2PGB

2021

Credit points: 15

Subject outline

This subject will introduce you to how variation in human molecular genetics may affect the pharmacokinetics and pharmacodynamics of drugs. Examples will focus on mutations associated with altered drug metabolism, excretion and potential for toxicity. Immune responses from a cellular and molecular perspective will be introduced incorporating innate immunity, inflammation, chemical cascades, adaptive immunity and cells of the immune system. Within this context immunopharmacology and immunotherapy will also be explored.

SchoolMolecular Sciences

Credit points15

Subject Co-ordinatorCristina Keightley

Available to Study Abroad/Exchange StudentsYes

Subject year levelYear Level 2 - UG

Available as ElectiveNo

Learning ActivitiesN/A

Capstone subjectNo

Subject particulars

Subject rules

PrerequisitesBIO1MGC OR BIO1CO OR BIO1OOS OR BIO1OF

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Quota Management StrategyN/A

Quota-conditions or rulesN/A

Special conditionsN/A

Minimum credit point requirementN/A

Assumed knowledgeN/A

Readings

Principles of Pharmacogenetics and Pharmacogenomics

Resource TypeRecommended

Resource RequirementN/A

AuthorAltman RB, Flockhart D, Goldstein DB

Year2012

Edition/VolumeN/A

PublisherCambridge Core.

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Basic Immunology: Functions and disorders of the immune system

Resource TypeRecommended

Resource RequirementN/A

AuthorAbbas, A B, Lichtman, A H

YearN/A

Edition/Volume6th ed

PublisherElsevier

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Career Ready

Career-focusedNo

Work-based learningNo

Self sourced or Uni sourcedN/A

Entire subject or partial subjectN/A

Total hours/days requiredN/A

Location of WBL activity (region)N/A

WBL addtional requirementsN/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Use an understanding of the variability within and between populations to interpret effects on drug metabolism.
02. Evaluate how the variability in pharmacogenetics can cause toxic levels of drugs to circulate.
03. Assess different causes of pharmaceutical toxicity including physiological change during human development, as a result of drug overdose or in a range of diseases
04. Explain the process of inflammation and the steps involved in initiation of the immune response to analyse drug interactions with the immune system.
05. Discuss how immunogenetics gives rise to clonal variation to fight infection and how immunopharmacotherapies can be used to target disease.

Subject options

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Start date between: and    Key dates

Albury-Wodonga, 2021, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Subject Instance Co-ordinatorCathryn Hogarth

Class requirements

LectureWeek: 30 - 42
Two 1.00 h lecture per week on weekdays during the day from week 30 to week 42 and delivered via face-to-face.
24-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 30 - 42
One 2.00 h tutorial per week on weekdays during the day from week 30 to week 42 and delivered via face-to-face.
24-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle% ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50 SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15 SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25 SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10 SILO1, SILO2, SILO3, SILO4, SILO5

Bendigo, 2021, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Subject Instance Co-ordinatorCristina Keightley

Class requirements

LectureWeek: 30 - 42
Two 1.00 h lecture per week on weekdays during the day from week 30 to week 42 and delivered via face-to-face.
24-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 30 - 42
One 2.00 h tutorial per week on weekdays during the day from week 30 to week 42 and delivered via face-to-face.
24-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle% ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50 SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15 SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25 SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10 SILO1, SILO2, SILO3, SILO4, SILO5

Singapore (PSB), 2021, Term L1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Subject Instance Co-ordinatorJennifer Selkirk-Bell

Class requirements

LectureWeek: 2 - 7
One 36.00 h lecture per study period on weekdays during the day from week 2 to week 7 and delivered via face-to-face.
36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 2 - 7
One 12.00 h tutorial per study period on weekdays during the day from week 2 to week 7 and delivered via face-to-face.
12-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle% ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50 SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15 SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25 SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10 SILO1, SILO2, SILO3, SILO4, SILO5