MOLECULAR GENETICS

GEN3HMG

2021

Credit points: 30

Subject outline

This subject introduces students to more advanced concepts and methods in human and molecular genetics. The topics covered include: genes and development including molecular regulation of embryogenesis, stems cells and cancer; Model organisms, including Mice and fruit fly; Immunogenetics; cancer; the genetic structure of human populations; molecular evidence for human evolution; forensic genetics, genomics applications and ethical implications; functional mapping of single and multifactorial human genetic diseases, introduction to gene and cellular therapy.

SchoolMolecular Sciences

Credit points30

Subject Co-ordinatorJodie Young

Available to Study Abroad/Exchange StudentsYes

Subject year levelYear Level 3 - UG

Exchange StudentsNo

Available as ElectiveNo

Learning ActivitiesN/A

Capstone subjectYes

Subject particulars

Subject rules

PrerequisitesGEN2MHG

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Quota Management StrategyMerit based quota management

Quota-conditions or rulesMerit based quota on academic performance in GEN2MHG.

Special conditionsThis subject is only available for repeating students who are prac exempt and have the approval of the subject coordinator.

Minimum credit point requirementN/A

Assumed knowledgeN/A

Readings

Concepts of Genetics

Resource TypeRecommended

Resource RequirementN/A

AuthorKlug et. al.

YearN/A

Edition/Volume10th, international edition

PublisherPearson

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Human Embryology and developmental

Resource TypeRecommended

Resource RequirementN/A

AuthorCarlson, B

Year2013

Edition/VolumeN/A

PublisherELSEVIER

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Human Molecular Genetics

Resource TypeRecommended

Resource RequirementN/A

AuthorStrachan, T and Read, A.P.

Year2011

Edition/Volume4th Edition

PublisherGARLAND SCIENCE

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Human Evolutionary Genetics

Resource TypeRecommended

Resource RequirementN/A

AuthorJobling M.A, Hurles. M and Tyler-Smith C

Year2004

Edition/VolumeN/A

PublisherGARLAND SCIENCE

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Principle of Development

Resource TypeRecommended

Resource RequirementN/A

AuthorWolpert, L and Tickle C

Year2010

Edition/VolumeN/A

PublisherOXFORD

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Janeway's Immunobiology

Resource TypeRecommended

Resource RequirementN/A

AuthorMurphy, Travers and Walport

YearN/A

Edition/Volume7th edition

PublisherGarland Science

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Genetics Analysis and Principles

Resource TypeRecommended

Resource RequirementN/A

AuthorBrooker, R

Year2011

Edition/VolumeN/A

PublisherMCGRAW HILL

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Career Ready

Career-focusedNo

Work-based learningNo

Self sourced or Uni sourcedN/A

Entire subject or partial subjectN/A

Total hours/days requiredN/A

Location of WBL activity (region)N/A

WBL addtional requirementsN/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Analyse and evaluate experimental and published data relating to molecular genetics experiments to prepare a comprehensive laboratory report.

02. Articulate and apply advanced genetics concepts and analytical methods in the genetic control of development, the structure and function of genes and chromosomes, human variation, genetic disease and genome biology.

03. Apply advanced molecular genetics laboratory methods to generate and analyse high quality experimental data.

04. Analyse, discuss and present research information to peers and a scientific audience.

05. Use bioinformatics to solve genetics problems.

06. Apply clinical problem solving skills to diagnose genetic diseases.

07. Discuss and debate the ethical implications of Genetics research.

Subject options

Select to view your study options…

Melbourne (Bundoora), 2021, Semester 1, Day

Overview

Online enrolmentNo

Maximum enrolment size100

Enrolment informationN/A

Subject Instance Co-ordinatorJodie Young

Class requirements

Laboratory ClassWeek: 10 - 22
One 6.00 h laboratory class per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

LectureWeek: 10 - 22
Four 1.00 h lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Or Delivery Method: On-Line

Assessments

Assessment element	Comments	Category	Contribution	Hurdle	%	ILO*
Group presentations (25min total) (1500 words equivalent) Group presentations including journal club presentation (10min) and case study presentation and questions (15 min)	N/A	N/A	N/A	No	16	SILO2, SILO4, SILO5, SILO6
Laboratory & ethical assessment (2000 words equivalent) Includes 3 reports, 2 worksheets, clay embryo model and ethics debate	N/A	N/A	N/A	No	24	SILO1, SILO2, SILO3, SILO5, SILO7
Two 1.5-hour exams (end of semester)	N/A	N/A	N/A	No	50	SILO2
Two mid-semester tests (30 minutes each)	N/A	N/A	N/A	No	10	SILO2

Singapore (PSB), 2021, Week 45-07, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment informationN/A

Subject Instance Co-ordinatorNoni Frankenberg

Class requirements

LectureWeek: 45 - 0
One 48.00 h lecture per study period on weekdays during the day from week 45 to week 0 and delivered via face-to-face.

PracticalWeek: 45 - 0
One 72.00 h practical per study period on weekdays during the day from week 45 to week 0 and delivered via face-to-face.
72 hours consisting of wet/ dry/simulation activities.

Assessments

Assessment element	Comments	Category	Contribution	Hurdle	%	ILO*
Group presentations (25min total) (1500 words equivalent) Group presentations including journal club presentation (10min) and case study presentation and questions (15 min)	N/A	N/A	N/A	No	16	SILO2, SILO4, SILO5, SILO6
Laboratory & ethical assessment (2000 words equivalent) Includes 3 reports, 2 worksheets, clay embryo model and ethics debate	N/A	N/A	N/A	No	24	SILO1, SILO2, SILO3, SILO5, SILO7
Two 1.5-hour exams (end of semester)	N/A	N/A	N/A	No	50	SILO2
Two mid-semester tests (30 minutes each)	N/A	N/A	N/A	No	10	SILO2

Singapore (PSB), 2021, Week 45-07, Night

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment informationN/A

Subject Instance Co-ordinatorNoni Frankenberg

Class requirements

LectureWeek: 45 - 0
One 48.00 h lecture per study period on weekdays at night from week 45 to week 0 and delivered via face-to-face.

PracticalWeek: 45 - 0
One 72.00 h practical per study period on weekdays at night from week 45 to week 0 and delivered via face-to-face.
72 hours consisting of wet/dry/simulation activities.

Assessments

Assessment element	Comments	Category	Contribution	Hurdle	%	ILO*
Group presentations (25min total) (1500 words equivalent) Group presentations including journal club presentation (10min) and case study presentation and questions (15 min)	N/A	N/A	N/A	No	16	SILO2, SILO4, SILO5, SILO6
Laboratory & ethical assessment (2000 words equivalent) Includes 3 reports, 2 worksheets, clay embryo model and ethics debate	N/A	N/A	N/A	No	24	SILO1, SILO2, SILO3, SILO5, SILO7
Two 1.5-hour exams (end of semester)	N/A	N/A	N/A	No	50	SILO2
Two mid-semester tests (30 minutes each)	N/A	N/A	N/A	No	10	SILO2