MEDICINAL AND BIOINORGANIC CHEMISTRY

CHE3MBC

2021

Credit points: 15

Subject outline

In this subject, the chemical principles encountered in the prerequisite subjects will be applied to issues of biological relevance within themes of medicinal chemistry, heterocyclic chemistry and bioinorganic chemistry. In the medicinal chemistry topic you will learn about issues related to pharmaceutical concerns from a chemical perspective, including an overview of the process of bringing new medicinal compounds to market. Most molecules of pharmaceutical relevance comprise organic heterocyclic rings containing nitrogen and oxygen; the synthetic strategies to access these compounds will be expanded in the heterocyclic chemistry topic with application to real-world examples. In the bioinorganic topic you will focus on the interplay of metal elements with biology from a chemical perspective # both essential metal elements such as iron and zinc, as well as the chemical basis for which toxic metal elements (e.g. mercury) act on the body, and finally how metal containing compounds can act as therapeutics. In this subject you will also gain experience conducting and interpreting laboratory experiments related to organic and bioinorganic chemistry.

SchoolMolecular Sciences

Credit points15

Subject Co-ordinatorBelinda Abbott

Available to Study Abroad/Exchange StudentsYes

Subject year levelYear Level 3 - UG

Available as ElectiveNo

Learning ActivitiesN/A

Capstone subjectNo

Subject particulars

Subject rules

Prerequisites Students must have completed CHE2FCA and CHE2FCB or Students must be admitted in the following course: SMCHS

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Quota Management StrategyN/A

Quota-conditions or rulesN/A

Special conditionsN/A

Minimum credit point requirementN/A

Assumed knowledgeN/A

Readings

Introduction to Medicinal Chemistry

Resource TypeRecommended

Resource RequirementN/A

AuthorPatrick G

Year2013

Edition/VolumeN/A

PublisherOxford University Press

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Organic Chemistry

Resource TypeRecommended

Resource RequirementN/A

AuthorMcMurry J

Year2016

Edition/VolumeN/A

PublisherThomson Brooks/Cole

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Career Ready

Career-focusedNo

Work-based learningNo

Self sourced or Uni sourcedN/A

Entire subject or partial subjectN/A

Total hours/days requiredN/A

Location of WBL activity (region)N/A

WBL addtional requirementsN/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Demonstrate and apply knowledge of principles and concepts of medicinal, heterocyclic and bioinorganic chemistry to solving problems in the biological and chemical sciences.
02. Exhibit professional integrity and safe laboratory practices when designing and performing experiments, collecting data and reporting findings.
03. Write coherent descriptions of chemical principles with biological relevance and report experimental results with well supported interpretations using correctly referenced professional prose.
04. Critically examine the literature relevant to medicinal and bioinorganic chemistry.

Subject options

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Start date between: and    Key dates

Melbourne (Bundoora), 2021, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Subject Instance Co-ordinatorBelinda Abbott

Class requirements

Laboratory ClassWeek: 32 - 43
Three 5.00 h laboratory class per study period on weekdays during the day from week 32 to week 43 and delivered via face-to-face.
The laboratory program consists of 3 classes (5 hours each) over the semester. A schedule of experiments will be made available to students on the LMS at the start of semester.

LectureWeek: 30 - 42
Four 1.00 h lecture per week on weekdays during the day from week 30 to week 42 and delivered via face-to-face.

SeminarWeek: 31 - 31
One 5.00 h seminar per study period on weekdays during the day from week 31 to week 31 and delivered via face-to-face.
Laboratory safety introduction will be held in the first week of semester.

Assessments

Assessment elementCommentsCategoryContributionHurdle% ILO*

2 hr written examination (equivalent to 1500 essay words)A 1.5 hour paper scheduled for 2 hours in the central examination period.

N/AN/AN/ANo35 SILO1

Tests (equivalent to 600 essay words)Two in class tests during semester.

N/AN/AN/ANo15 SILO1

Essay assignment (equivalent to 450 essay words)One essay during semester for the bioinorganic chemistry component.

N/AN/AN/ANo10 SILO4

Online quizzes (equivalent to 450 essay words)Two LMS quizzes during semester.

N/AN/AN/ANo10 SILO1

Laboratory work, written reports (equivalent to 1500 essay words)HURDLE for subject pass, from accreditation with RACI. Students must complete a minimum 75% of lab assessment, and must obtain a score of at least 50% for the laboratory component of the subject. Develops and assess competency in practical skills, and in data handling and reporting.

N/AN/AN/AYes30 SILO1, SILO2, SILO3