MEDICINAL CHEMISTRY A

CHE2MCA

2021

Credit points: 15

Subject outline

Students will be introduced to the chemical principles that are required to understand the action and behaviours of a drug compound. The main areas of study include an introduction to the chemistry and nomenclature of carbohydrates, lipids, steroids and heterocyclic compounds and some of their reactions. This unit will provide an understanding of how the chemical structure and behaviour of drug molecules relate to the activity of drugs in biological systems, and how this knowledge can be used to devise strategies for drug design and principles of drug structure-activity relationships (SAR and QSAR), drug-receptor interactions and drugs metabolism. This unit will also contain a computer based practical component.

SchoolMolecular Sciences

Credit points15

Subject Co-ordinatorJasim Al-Rawi

Available to Study Abroad/Exchange StudentsYes

Subject year levelYear Level 2 - UG

Available as ElectiveNo

Learning ActivitiesN/A

Capstone subjectNo

Subject particulars

Subject rules

Prerequisites(CHE1C1B AND CHE1C1A) OR (CHE1CHF AND CHE1APL)

Co-requisitesN/A

Incompatible subjectsN/A

Equivalent subjectsN/A

Quota Management StrategyN/A

Quota-conditions or rulesN/A

Special conditionsN/A

Minimum credit point requirementN/A

Assumed knowledgeN/A

Readings

An Introduction to Medicinal Chemistry

Resource TypePrescribed

Resource RequirementN/A

AuthorPatrick, G.

Year2013

Edition/VolumeN/A

PublisherOxford University Press

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Medicinal Chemistry: An Introduction

Resource TypeRecommended

Resource RequirementN/A

AuthorThomas, G.

Year2007

Edition/VolumeN/A

PublisherWiley

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Organic chemistry

Resource TypePrescribed

Resource RequirementN/A

AuthorBruice, P. Y.

Year2017

Edition/VolumeN/A

PublisherPearson

ISBNN/A

Chapter/article titleN/A

Chapter/issueN/A

URLN/A

Other descriptionN/A

Source locationN/A

Career Ready

Career-focusedNo

Work-based learningNo

Self sourced or Uni sourcedN/A

Entire subject or partial subjectN/A

Total hours/days requiredN/A

Location of WBL activity (region)N/A

WBL addtional requirementsN/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Apply understanding of the chemistry of important biological molecules such as carbohydrates, lipids, steroids and heterocyclic molecules to medicinal products.
02. Apply advanced understanding of the chemistry of organic compounds and its impact on syntheses to enhance drug efficacy.
03. Use the major concepts and language of pharmaceutical and medicinal chemistry correctly.
04. Determine likely routes of administration through recognition of drug structures, identification and prediction of likely metabolic and elimination pathways, solubility and metabolism.
05. Devise strategies for drug design and principles of drug structure-activity relationships (SAR and QSAR).

Subject options

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Start date between: and    Key dates

Albury-Wodonga, 2021, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Subject Instance Co-ordinatorKeith White

Class requirements

Computer LaboratoryWeek: 13 - 16
One 3.00 h computer laboratory per study period on weekdays during the day from week 13 to week 16 and delivered via face-to-face.
Computer Laboratory simulation

LectureWeek: 10 - 22
Three 1.00 h lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

PracticalWeek: 15 - 15
One 3.00 h practical per study period on weekdays during the day from week 15 to week 15 and delivered via face-to-face.

TutorialWeek: 11 - 22
One 1.00 h tutorial per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.

Assessments

Assessment elementCommentsCategoryContributionHurdle% ILO*
One 3-hour end-of-semester written examination (3,000-words equivalent)N/AN/AN/ANo60 SILO1, SILO2, SILO3, SILO4, SILO5
Two in-class tests (15% each) (600-words equivalent in total)N/AN/AN/ANo30 SILO1, SILO2, SILO3
Two laboratory reports (5% each) (300-words equivalent in total)N/AN/AN/ANo10 SILO2, SILO3

Bendigo, 2021, Semester 1, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Subject Instance Co-ordinatorJasim Al-Rawi

Class requirements

Computer LaboratoryWeek: 13 - 16
One 3.00 h computer laboratory per study period on weekdays during the day from week 13 to week 16 and delivered via face-to-face.
Computer Laboratory simulation

LectureWeek: 10 - 22
Three 1.00 h lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

PracticalWeek: 15 - 15
One 3.00 h practical per study period on weekdays during the day from week 15 to week 15 and delivered via face-to-face.

TutorialWeek: 11 - 22
One 1.00 h tutorial per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.

Assessments

Assessment elementCommentsCategoryContributionHurdle% ILO*
One 3-hour end-of-semester written examination (3,000-words equivalent)N/AN/AN/ANo60 SILO1, SILO2, SILO3, SILO4, SILO5
Two in-class tests (15% each) (600-words equivalent in total)N/AN/AN/ANo30 SILO1, SILO2, SILO3
Two laboratory reports (5% each) (300-words equivalent in total)N/AN/AN/ANo10 SILO2, SILO3