METABOLIC BIOCHEMISTRY AND CELL BIOLOGY

BCH2MBC

2019

Credit points: 15

Subject outline

Biochemistry is concerned with the function of biological systems at the molecular level. It is central to most studies in biology and life sciences and is directly related to biomedical research and biotechnology. In this subject, students are introduced to cell biology and cell metabolism, building on the concepts developed in Introduction to Biochemistry and Molecular Biology (BCH2IBM). Students study the generation of energy in cells through the oxidation of carbohydrates and lipids; the formation of ATP, the energy currency of cells; lipids, cellular membranes and compartmentation; and the signalling processes that co-ordinate and regulate cellular activity. The practical work reinforces basic experimental skills and includes exercises on metabolism and cell biology.

SchoolSchool of Molecular Sciences/LIMS

Credit points15

Subject Co-ordinatorSteve Jones

Available to Study Abroad StudentsYes

Subject year levelYear Level 2 - UG

Exchange StudentsYes

Subject particulars

Subject rules

Prerequisites One of (BIO1OF or BIO1MGC or HBS1HBA or BIO1CO) and one of (CHE1CHF or CHE1GEN or CHE1C1A) and one of (CHE1APL or CHE1C1B or DTN1CFC) OR Must be admitted in to LWLBM (Bachelor of Laws/Bachelor of Biomedicine).

Co-requisitesN/A

Incompatible subjects BCH2BMB, AGR2BAS, AGR2BAA, BCM202

Equivalent subjectsN/A

Special conditions Students are also expected to have previously attempted (but not necessarily to have passed) BCH2IBM.

Readings

Resource TypeTitleResource RequirementAuthor and YearPublisher
ReadingsBCH2MBC Subject ManualPrescribedDepartment of Biochemistry and GeneticsAVAILABLE THROUGH LA TROBE UNIVERSITY BOOKSHOP
ReadingsLehninger Principles of Biochemistry (2016, 7e)RecommendedDavid L Nelson & Michael M CoxW.H. FREEMAN & COMPANY, NEW YORK

Graduate capabilities & intended learning outcomes

01. Apply appropriate vocabulary to describe fundamental concepts in biochemistry and molecular biology.

Activities:
In lectures, students will be instructed in energy metabolism (glycolysis, the Krebs cycle, the electron transport chain and oxidative phosphorylation), lipids, membranes and compartmentation, and techniques in molecular cell biology. These concepts will be reinforced by small-group discussions in lectorial (large-scale tutorial) sessions. The students' understanding of these concepts will be assessed by short-answer and/or multiple-choice questions in lectorial quizzes, and by short-answer questions in formal examinations.
Related graduate capabilities and elements:
Literacies and Communication Skills (Speaking,Quantitative Literacy)
Inquiry and Analytical Skills (Critical Thinking,Creative Problem-solving,Inquiry/Research)
Discipline -Specific Knowledge and Skills (Discipline-Specific Knowledge and Skills)

02. Apply biochemical and molecular biology techniques, principles and methodologies in addressing research problems.

Activities:
In laboratory classes, students will apply and build on their basic laboratory skills to investigate aspects of cellular metabolism, and they will gain hands on experience in a range of techniques in molecular cell biology. The students' ability to carry out these techniques will be assessed on the basis of the quality of their experimental results, and this will contribute to their 'laboratory performance' mark. The students' understanding of the underlying principles will be assessed through prac reports.
Related graduate capabilities and elements:
Inquiry and Analytical Skills (Critical Thinking,Creative Problem-solving,Inquiry/Research)
Discipline -Specific Knowledge and Skills (Discipline-Specific Knowledge and Skills)

03. Develop and deliver a coherent and informed oral presentation on biochemical concepts.

Activities:
Students will be instructed on aspects of oral presentations (including the appropriate use of visual aids) in a workshop which will address the preparation of the oral presentation for their research assignments. These oral presentations will be jointly prepared and presented by student pairs. They will be peer-assessed by the other members of the pair's prac group, following a comprehensive marking scheme.
Related graduate capabilities and elements:
Literacies and Communication Skills (Speaking,Quantitative Literacy)

04. Employ laboratory practice to acceptable standards in terms of safety, professional conduct and keeping accurate records of experimental data.

Activities:
Students will complete an induction exercise (not formally assessed) where they are introduced to various aspects of biochemical laboratory practice: appropriate behaviour, safe handling of equipment and reagents, principles of risk assessment, appropriate record keeping. These factors will be assessed during all subsequent prac sessions as a component of the laboratory performance mark.
Related graduate capabilities and elements:
Personal and Professional Skills (Ethical behaviour,Study and Learning Skills)

05. Compute basic mathematical calculations and prepare graphic representations to aid the interpretation of biochemical data consistent with scientific standards.

Activities:
Calculations and graphical analyses will be commonly performed as part of laboratory practicals, and instruction will be provided during pre-prac talks, in the laboratory manual and/or by demonstrators during prac sessions. Calculations and graphic representations will be assessed as an integral component of practical report marking.
Related graduate capabilities and elements:
Literacies and Communication Skills (Speaking,Quantitative Literacy)

06. Demonstrate independent learning and research skills by locating, interrogating and evaluating relevant scientific information.

Activities:
Students will be instructed on the selection of appropriate and reliable sources of information, with particular emphasis on material sourced from the internet, during the workshop on oral presentations. The gathering and critical analysis of information derived from multiple literature-based sources will be assessed as a component of the oral presentation given on the research assignment. The prac course will include an experimental design component which will be assessed partly on the basis of inclusion of appropriate controls in student-designed experiments and the use of relevant information sources.
Related graduate capabilities and elements:
Inquiry and Analytical Skills (Critical Thinking,Creative Problem-solving,Inquiry/Research)
Personal and Professional Skills (Ethical behaviour,Study and Learning Skills)

07. Participate as an effective team member in a laboratory environment and collaborate effectively on research projects.

Activities:
In workshop sessions, small groups of students will engage in discussions to which all members will be expected to contribute. In practical sessions students will usually work in pairs but will sometimes collaborate in larger groups. They will be instructed on aspects of team-work by demonstrators. The ability of students to work effectively as team-members will be assessed as a component of the laboratory performance mark. Students will work in pairs to jointly prepare and deliver to their peers an oral presentation on their chosen research assignment topic. They will be given instruction on various aspects of this team-based task during the workshop on oral presentations.
Related graduate capabilities and elements:
Literacies and Communication Skills (Speaking,Quantitative Literacy)
Literacies and Communication Skills (Speaking,Quantitative Literacy)
Inquiry and Analytical Skills (Critical Thinking,Creative Problem-solving,Inquiry/Research)
Inquiry and Analytical Skills (Critical Thinking,Creative Problem-solving,Inquiry/Research)
Inquiry and Analytical Skills (Critical Thinking,Creative Problem-solving,Inquiry/Research)
Personal and Professional Skills (Ethical behaviour,Study and Learning Skills)
Discipline -Specific Knowledge and Skills (Discipline-Specific Knowledge and Skills)

Subject options

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Start date between: and    Key dates

Albury-Wodonga, 2019, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorSteve Jones

Class requirements

Laboratory Class Week: 31 - 43
One 3.0 hours laboratory class every two weeks on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Type: Directed Learning Activity Or Delivery Method: On-Line (equivalent to 1.5hr per week)"

WorkShop Week: 31 - 43
One 1.0 hours workshop per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Unscheduled Online Class Week: 31 - 43
Two 1.0 hours unscheduled online class per week on any day including weekend during the day from week 31 to week 43 and delivered via online.

Assessments

Assessment elementComments% ILO*
End of semester examination - 2 hr (2,000-words equivalent)40 01, 07
Five workshop quizzes (70-words equivalent each, 350- words equivalent total)10 01, 06
Mid-semester test (45 min) (750- words equivalent)15 01
Prac work: worksheet or brief prac report x6 (20%) & lab performance (5%) (900-words equiv total)25 02, 03, 04, 05, 06
Research assignment (10min oral presentation, prepared & delivered in pairs) (500-words equivalent)10 01, 03, 06

Bendigo, 2019, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorSteve Jones

Class requirements

Laboratory Class Week: 31 - 43
One 3.0 hours laboratory class every two weeks on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
"Type: Directed Learning Activity Or Delivery Method: On-Line (equivalent to 1.5hr per week. "

WorkShop Week: 31 - 43
One 1.0 hours workshop per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Unscheduled Online Class Week: 31 - 43
Two 1.0 hours unscheduled online class per week on any day including weekend during the day from week 31 to week 43 and delivered via online.

Assessments

Assessment elementComments% ILO*
End of semester examination - 2 hr (2,000-words equivalent)40 01, 07
Five workshop quizzes (70-words equivalent each, 350- words equivalent total)10 01, 06
Mid-semester test (45 min) (750- words equivalent)15 01
Prac work: worksheet or brief prac report x6 (20%) & lab performance (5%) (900-words equiv total)25 02, 03, 04, 05, 06
Research assignment (10min oral presentation, prepared & delivered in pairs) (500-words equivalent)10 01, 03, 06

Melbourne, 2019, Semester 2, Day

Overview

Online enrolmentYes

Maximum enrolment size350

Enrolment information Quota due to limited access to laboratory space. Merit based quota. Priority is given to students for whom BCH2MBC is a core subject. If the quota is exceeded, students will be selected based on WAM in 1st year subjects.

Subject Instance Co-ordinatorSteve Jones

Class requirements

Laboratory Class Week: 31 - 43
One 3.0 hours laboratory class every two weeks on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

WorkShop Week: 31 - 43
One 1.0 hours workshop per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.

Unscheduled Online Class Week: 31 - 43
Two 1.0 hours unscheduled online class per week on any day including weekend during the day from week 31 to week 43 and delivered via online.

Assessments

Assessment elementComments% ILO*
End of semester examination - 2 hr (2,000-words equivalent)40 01, 07
Five workshop quizzes (70-words equivalent each, 350- words equivalent total)10 01, 06
Mid-semester test (45 min) (750- words equivalent)15 01
Prac work: worksheet or brief prac report x6 (20%) & lab performance (5%) (900-words equiv total)25 02, 03, 04, 05, 06
Research assignment (10min oral presentation, prepared & delivered in pairs) (500-words equivalent)10 01, 03, 06

Singapore (PSB), 2019, Term L2, Day

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorNoni Frankenberg

Class requirements

Laboratory Class Week: 11 - 15
One 18.0 hours laboratory class per study period on weekdays during the day from week 11 to week 15 and delivered via face-to-face.
"18-hours of Practical or Directed Learning Activities during the teaching period and delivered via face-to-face or online."

Lecture Week: 11 - 15
One 36.0 hours lecture per study period on weekdays during the day from week 11 to week 15 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online. "

Assessments

Assessment elementComments% ILO*
End of semester examination - 2 hr (2,000-words equivalent)40 01, 07
Five workshop quizzes (70-words equivalent each, 350- words equivalent total)10 01, 06
Mid-semester test (45 min) (750- words equivalent)15 01
Prac work: worksheet or brief prac report x6 (20%) & lab performance (5%) (900-words equiv total)25 02, 03, 04, 05, 06
Research assignment (10min oral presentation, prepared & delivered in pairs) (500-words equivalent)10 01, 03, 06

Singapore (PSB), 2019, Term L2, Night

Overview

Online enrolmentYes

Maximum enrolment sizeN/A

Enrolment information

Subject Instance Co-ordinatorNoni Frankenberg

Class requirements

Laboratory Class Week: 11 - 15
One 18.0 hours laboratory class per study period on weekdays at night from week 11 to week 15 and delivered via face-to-face.
"18-hours of Practical or Directed Learning Activities during the teaching period and delivered via face-to-face or online."

Lecture Week: 11 - 15
One 36.0 hours lecture per study period on weekdays at night from week 11 to week 15 and delivered via face-to-face.
"36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online."

Assessments

Assessment elementComments% ILO*
End of semester examination - 2 hr (2,000-words equivalent)40 01, 07
Five workshop quizzes (70-words equivalent each, 350- words equivalent total)10 01, 06
Mid-semester test (45 min) (750- words equivalent)15 01
Prac work: worksheet or brief prac report x6 (20%) & lab performance (5%) (900-words equiv total)25 02, 03, 04, 05, 06
Research assignment (10min oral presentation, prepared & delivered in pairs) (500-words equivalent)10 01, 03, 06