PHARMACEUTICAL FORMULATION B
Credit points: 15
Pharmacists dispense many dosage forms and need to understand their strengths and limitations. Students will be taught the design and formulation of two-phase pharmaceutical products including suspensions and emulsions. Major topics include: pharmaceutically relevant physicochemical phenomena, quality assurance, preparation and extemporaneous dispensing of pharmaceutical preparations, including pharmaceutical calculations.
SchoolSchool of Molecular Sciences/LIMS
Subject Co-ordinatorChristina Dennis
Available to Study Abroad StudentsNo
Subject year levelYear Level 2 - UG
Prerequisites Must be admitted in SHPB and have passed PHA1PFA.
|Resource Type||Title||Resource Requirement||Author and Year||Publisher|
|Readings||Aulton's Pharmaceutics: the design and manufacture of Medicines||Prescribed||Aulton, ME and Taylor, K. 2013||4TH ED., LONDON: CHURCHILL LIVINGSTONE|
|Readings||Australian Pharmaceutical Formulary and Handbook||Prescribed||Sansom, L (ed), 2015||23rd ED., CANBERRA: PHARMACEUTICAL|
|Readings||Martindale: the complete drug reference||Recommended||Brayfield, A (ed). 2014||38TH ED., 2014 LONDON: PHARMACEUTICAL PRESS|
|Readings||Pharmaceutical Practice||Recommended||Rees JA, Smith, I. and Watson J 2014||5TH ED., LONDON: CHURCHILL LIVINGSTONE|
|Readings||Physicochemical Principles of Pharmacy||Recommended||Florence, AT& Attwood, D 2011||5TH ED., BASINGSTOKE: MACMILLAN|
|Readings||Extemporaneous Dispensing Record Sheets||Prescribed||La Trobe University 2018||Available from the bookshop|
Graduate capabilities & intended learning outcomes
01. Meet the Pharmaceutical Society of Australia (PSA) Professional Practice Standard for Compounding by preparing and dispensing 2-phase products and complex solutions.
- Activity: tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, including exam. Students must prepare and dispense solution and two-phase formulations. Marks are awarded for labelling and documentation accuracy, elegance of product. Quality assurance protocols are used throughout, and students must be able to self-assess the quality of their products.
02. Explain and predict the properties of 2-phase systems and discuss their formulation.
- Activity: Lectures, tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, which may include an oral component, written exam. In these assessments students are asked to select an appropriate topical product for an application and justify this choice.
03. Use knowledge of topical formulations to justify the selection of an appropriate topical product for a specified use.
- Activity: Lectures, tutorials, practical work. Assessment: Assessed in the in-class practical test, practical skills assessment, which includes an oral component, written exam. In these assessments students are asked to select an appropriate topical product for an application and justify this choice.
04. Accurately perform pharmaceutical calculations.
- Activity: Lectures, tutorials, on-line quiz bank. Assessment: Students should successfully complete the on-line quizzes where they must achieve a score of 90% on quiz 3 to sit the calculation test. They must achieve 90% on quiz 3 to pass the subject. The question bank is accessible via the LMS - students can repeat quizzes as often as they like. A Question and Answer forum is set up to encourage collaborative problem-solving. There is also a dedicated tutorial for calculations and problem-solving. There are also calculation questions on the written exam, and skills in calculations are required in the practical assessment.
05. Discuss the choice of packaging and application of quality assurance to compounded products.
- Activity: Lectures, tutorials. Assessment: Written exam.
Select to view your study options…
Bendigo, 2019, Semester 1, Day
Maximum enrolment sizeN/A
Subject Instance Co-ordinatorChristina Dennis
Two 1.0 hours tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Seven 3.0 hours practical per study period on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
Two 1.0 hours lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
|2 hour examination (2,000-words equivalent)||50||02, 01, 03, 05, 04|
|Calculation competency test (800-words equivalent)||Students undertake 3 on-line quizzes with immediate feedback Must achieve 90% on each quiz to open the next quiz including quiz 3 to sit this Calculations Competency test.||25||04|
|In-class practical test (1,000-words equivalent)||Students who fail to complete at least 1 competent product are required to repeat product to competency under guidance. Hurdle requirement at least one competent product produced.||25||03, 01|