PHARMACY PRACTICE AND THERAPEUTICS B (METABOLIC AND ENDOCRINE)

PHA3THB

2020

Credit points: 15

Subject outline

This subject will integrate the teaching of pharmacology, medicinal chemistry and pharmacy practice relating to the use of drugs for gastroenterology, hepatic, reproductive and endocrine disorders. Students will initially explore the mechanism of action of these drugs, specifically how they affect biochemical and physiological processes at the cellular and organ level, and then relate this to the overall clinical effect on the individual. The medicinal chemistry of these drugs will then be explored so that structure-function relationships can be determined at the molecular level. Finally, the pharmacy practice issues relating to these conditions and medications will be addressed, in a manner that highlights how these drugs can ameliorate the various disease states, and affect the overall clinical condition of the patient.

School: Molecular Sciences (Pre 2022)

Credit points: 15

Subject Co-ordinator: Nick Standen

Available to Study Abroad/Exchange Students: Yes

Subject year level: Year Level 3 - UG

Exchange Students: No

Available as Elective: No

Learning Activities: N/A

Capstone subject: No

Subject particulars

Subject rules

Prerequisites: PHA2THA and must be admitted into the Bachelor of Pharmacy course (SHPB)

Co-requisites: N/A

Incompatible subjects: N/A

Equivalent subjects: PHA3PGC

Quota Management Strategy: N/A

Quota-conditions or rules: N/A

Special conditions: N/A

Minimum credit point requirement: N/A

Assumed knowledge: N/A

Learning resources

An Introduction to Medicinal Chemistry

Resource Type: Book

Resource Requirement: Recommended

Author: Patrick, G

Year: 2009

Edition/Volume: 4TH ED

Publisher: OXFORD, NEW YORK

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Goodman & Gilman's Manual of Pharmacology and Therapeutics

Resource Type: Book

Resource Requirement: Prescribed

Author: Brunton, L, Knollman B, & Hilal-Dandan R

Year: 2013

Edition/Volume: soft cover portable volume 10TH ED

Publisher: MCGRAW-HILL

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Therapeutic Guidelines: Gastrointestinal. Version 4

Resource Type: Book

Resource Requirement: Recommended

Author: Therapeutic Guidelines Ltd

Year: 2006

Edition/Volume: N/A

Publisher: THERAPEUTIC GUIDELINES LIMITED, MELBOURNE

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Therapeutic Guidelines: Endocrinology. Version 5

Resource Type: Book

Resource Requirement: Recommended

Author: Therapeutic Guidelines Ltd. Expert Writing Group

Year: 2011

Edition/Volume: N/A

Publisher: THERAPEUTIC GUIDELINES LTD, MELBOURNE.

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Clinical Pharmacy and Therapeutics

Resource Type: Book

Resource Requirement: Recommended

Author: Walker R & Whittlesea C Eds

Year: 2011

Edition/Volume: 5TH ED

Publisher: EDINBURGH: CHURCHILL LIVINGSTONE

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Pharmacology

Resource Type: Book

Resource Requirement: Recommended

Author: Rang HP, Dale MM, Ritter JM and Moore PK

Year: 2016

Edition/Volume: 8TH ED

Publisher: CHURCHILL LIVINGSTONE, EDINBURGH

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Career Ready

Career-focused: No

Work-based learning: No

Self sourced or Uni sourced: N/A

Entire subject or partial subject: N/A

Total hours/days required: N/A

Location of WBL activity (region): N/A

WBL addtional requirements: N/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Explain the pathophysiology for a selection of disease states associated with the endocrine system, reproductive system and body metabolism.

02. Relate the relevant class of drugs to activity at the molecular level, specifically, effect on relevant receptors and other regulatory molecules and processes.

03. Describe and explain the relationship between drug actions and therapeutic outcomes, specifically in the amelioration of disease states associated with the endocrine system or body metabolism.

04. Describe the absorption, elimination and metabolism of endocrine and gastrointestinal drugs and relate this to clinical practice and how pharmacogenetics affects this.

05. Anticipate and rationalize interaction between drugs(including over-the-counter (OTC and other substances)

06. Follow guidelines to critically assess drug use and disease states in a defined case study scenario.

07. Discuss alterations in human metabolism as a consequence of altered liver function.

Bendigo, 2020, Semester 1, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Enrolment information: N/A

Subject Instance Co-ordinator: Richard Summers

Class requirements

LectureWeek: 10 - 22
Three 1.00 hour lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

TutorialWeek: 13 - 22
Six 1.00 hour tutorial per study period on weekdays during the day from week 13 to week 22 and delivered via face-to-face.

WorkShopWeek: 11 - 22
One 2.00 hours workshop per week on weekdays during the day from week 11 to week 22 and delivered via face-to-face.

Assessments

Assessment element	Comments	Category	Contribution	Hurdle	%	ILO*
2 x case studies (1000 words equiv. in total)	N/A	N/A	N/A	No	40	SILO1, SILO2, SILO3, SILO6, SILO7
One 2-hour examination	N/A	N/A	N/A	No	50	SILO1, SILO2, SILO3, SILO4, SILO5, SILO6, SILO7
Mid-semester test (1 hour) (1000 words equiv)	N/A	N/A	N/A	No	10	SILO1, SILO2, SILO3, SILO4, SILO5, SILO6, SILO7