PHARMACOLOGY B

PHA2PGB

2020

Credit points: 15

Subject outline

This subject will introduce you to how variation in human molecular genetics may affect the pharmacokinetics and pharmacodynamics of drugs. Examples will focus on mutations associated with altered drug metabolism, excretion and potential for toxicity. Immune responses from a cellular and molecular perspective will be introduced incorporating innate immunity, inflammation, chemical cascades, adaptive immunity and cells of the immune system. Within this context immunopharmacology and immunotherapy will also be explored.

School: Molecular Sciences (Pre 2022)

Credit points: 15

Subject Co-ordinator: Maria Cristina Keightley

Available to Study Abroad/Exchange Students: Yes

Subject year level: Year Level 2 - UG

Available as Elective: No

Learning Activities: N/A

Capstone subject: No

Subject particulars

Subject rules

Prerequisites: BIO1OF OR BIO1CO OR BIO1OOS OR BIO1MGC

Co-requisites: N/A

Incompatible subjects: N/A

Equivalent subjects: N/A

Quota Management Strategy: N/A

Quota-conditions or rules: N/A

Special conditions: N/A

Minimum credit point requirement: N/A

Assumed knowledge: N/A

Learning resources

Basic Immunology: Functions and disorders of the immune system

Resource Type: Book

Resource Requirement: Recommended

Author: Abbas, A B, Lichtman, A H

Year: N/A

Edition/Volume: 6th ed

Publisher: Elsevier

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Principles of Pharmacogenetics and Pharmacogenomics

Resource Type: Book

Resource Requirement: Recommended

Author: Altman RB, Flockhart D, Goldstein DB

Year: 2012

Edition/Volume: N/A

Publisher: Cambridge Core.

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Career Ready

Career-focused: No

Work-based learning: No

Self sourced or Uni sourced: N/A

Entire subject or partial subject: N/A

Total hours/days required: N/A

Location of WBL activity (region): N/A

WBL addtional requirements: N/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

COMMUNICATION - Communicating and Influencing
DISCIPLINE KNOWLEDGE AND SKILLS
INQUIRY AND ANALYSIS - Creativity and Innovation
INQUIRY AND ANALYSIS - Critical Thinking and Problem Solving
INQUIRY AND ANALYSIS - Research and Evidence-Based Inquiry
PERSONAL AND PROFESSIONAL - Ethical and Social Responsibility
PERSONAL AND PROFESSIONAL - Leadership and Teamwork

Intended Learning Outcomes

01. Use an understanding of the variability within and between populations to interpret effects on drug metabolism.
02. Evaluate how the variability in pharmacogenetics can cause toxic levels of drugs to circulate.
03. Assess different causes of pharmaceutical toxicity including physiological change during human development, as a result of drug overdose or in a range of diseases
04. Explain the process of inflammation and the steps involved in initiation of the immune response to analyse drug interactions with the immune system.
05. Discuss how immunogenetics gives rise to clonal variation to fight infection and how immunopharmacotherapies can be used to target disease.

Albury-Wodonga, 2020, Semester 2, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Cathryn Hogarth

Class requirements

LectureWeek: 31 - 43
Two 1.00 hour lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
24-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 31 - 43
One 2.00 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
24-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10SILO1, SILO2, SILO3, SILO4, SILO5

Bendigo, 2020, Semester 2, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Maria Cristina Keightley

Class requirements

LectureWeek: 31 - 43
Two 1.00 hour lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
24-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 31 - 43
One 2.00 hours tutorial per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
24-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10SILO1, SILO2, SILO3, SILO4, SILO5

Singapore (PSB), 2020, Term 2, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

LectureWeek: 21 - 31
Twenty four 1.00 hour lecture per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.
24-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 21 - 31
Twenty four 1.00 hour tutorial per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.
24-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10SILO1, SILO2, SILO3, SILO4, SILO5

Singapore (PSB), 2020, Term 2, Night

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

LectureWeek: 21 - 31
Twenty four 1.00 hour lecture per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.
24-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 21 - 31
Twenty four 1.00 hour tutorial per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.
24-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10SILO1, SILO2, SILO3, SILO4, SILO5

Singapore (PSB), 2020, Term L1, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Jennifer Selkirk-Bell

Class requirements

LectureWeek: 2 - 7
One 36.00 hours lecture per study period on weekdays during the day from week 2 to week 7 and delivered via face-to-face.
36-hours of Blended Lectures and Online Learning Activities in the teaching period delivered as a combination of face-to-face and online.

TutorialWeek: 2 - 7
One 12.00 hours tutorial per study period on weekdays during the day from week 2 to week 7 and delivered via face-to-face.
12-hours of Tutorial or Directed Learning Activities during the teaching period and delivered via face-to-face or online.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

2-hour end of semester written examination (2,000-words equivalent)

N/AN/AN/ANo50SILO1, SILO2, SILO3, SILO4, SILO5

1-hour mid-semester test (1,000 words equivalent)

N/AN/AN/ANo15SILO1, SILO2, SILO3

One group review article (750-words per student)

N/AN/AN/ANo25SILO1, SILO2, SILO3

3 x online tests during semester (500-words equivalent)

N/AN/AN/ANo10SILO1, SILO2, SILO3, SILO4, SILO5