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MOLECULAR GENETICS

GEN2MHG

2020

Credit points: 15

Subject outline

This subject introduces students to concepts and methods in molecular and human genetics. Topics covered include: DNA and RNA structure, DNA replication, chromosome structure, transposable elements, transcription, translation, regulation of gene expression, recombination, DNA damage and repair, molecular biology and recombinant technologies, modes of inheritance, single and multigene diseases, epigenetic diseases, diagnosis of genetic diseases, gene therapy, personalised medicine, biotechnology, applications of genetic model organisms, bioinformatics, DNA in forensic sciences, synthetic life, human evolution and variation.

School: Molecular Sciences (Pre 2022)

Credit points: 15

Subject Co-ordinator: Christine Hawkins

Available to Study Abroad/Exchange Students: Yes

Subject year level: Year Level 2 - UG

Available as Elective: No

Learning Activities: N/A

Capstone subject: No

Subject particulars

Subject rules

Prerequisites: BIO1EEB OR BIO1MGC OR BIO1GEN

Co-requisites: N/A

Incompatible subjects: N/A

Equivalent subjects: N/A

Quota Management Strategy: N/A

Quota-conditions or rules: N/A

Special conditions: N/A

Minimum credit point requirement: N/A

Assumed knowledge: N/A

Learning resources

Human Molecular Geneticsition

Resource Type: Book

Resource Requirement: Recommended

Author: Strachan, T and Read, A.P.

Year: 2011

Edition/Volume: 4th Edition

Publisher: Garland Science

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Concepts in Genetics

Resource Type: Book

Resource Requirement: Recommended

Author: Klug, Cummings, Spencer and Palladino

Year: 2014

Edition/Volume: 10th Edition or later

Publisher: Pearson Education

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Career Ready

Career-focused: No

Work-based learning: No

Self sourced or Uni sourced: N/A

Entire subject or partial subject: N/A

Total hours/days required: N/A

Location of WBL activity (region): N/A

WBL addtional requirements: N/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Produce well-structured, scientifically accurate reports using grammatically correct English, which present evidence-based explanations of laboratory experiments.
02. As part of a team, deliver a clear, engaging and scientifically accurate oral presentation on a scientific topic you have researched.
03. Perform basic calculations required for design of molecular biology experiments.
04. Demonstrate independent research skills by locating and evaluating relevant scientific information.
05. Place theoretical and/or experimental information into the appropriate discipline specific context.
06. Demonstrate knowledge and understanding by explaining genetics concepts, including molecular mechanisms underpinning inheritance and expression of genetic traits.
07. Apply basic experimental molecular genetic techniques in research.
08. Apply knowledge of molecular structures and mechanisms to current medical, environmental and ethical issues related to genetics.

Melbourne (Bundoora), 2020, Semester 2, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Christine Hawkins

Class requirements

Laboratory ClassWeek: 31 - 43
One 3.00 hours laboratory class per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
Or Type: Directed Learning Activity Or Delivery Method: On-Line

LectureWeek: 31 - 43
Three 1.00 hour lecture per week on weekdays during the day from week 31 to week 43 and delivered via face-to-face.
Or Delivery Method: On-Line In-class exam held instead of lecture at end of week 4. This would ideally be held in a large, ideally non-tiered venue so we can restrict the students ability to see each others answers

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

Worksheets (400 words equivalent)

N/AN/AN/ANo14SILO1, SILO3, SILO4, SILO5, SILO6, SILO7

Practical reports (one major, one minor) (1400 words equivalent)Major report around 950 words; minor report around 450 words

N/AN/AN/ANo25SILO1, SILO3, SILO4, SILO5, SILO6, SILO7, SILO8

Oral presentation (10 min) (250 words equivalent per student)A group of four students will give a joint ten minute presentation: equivalent to 1000 words

N/AN/AN/ANo10SILO2, SILO4, SILO5, SILO6, SILO8

On-line quizzes (weeks 2-12) (1000 words equivalent)

N/AN/AN/ANo11SILO5, SILO6, SILO7, SILO8

Exam (1 hour)

N/AN/AN/ANo30SILO5, SILO6, SILO8

Mid-semester test (30min)

N/AN/AN/ANo10SILO5, SILO6, SILO8

Singapore (PSB), 2020, Term 2, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Yeliz Boglev

Class requirements

LectureWeek: 21 - 31
Thirty six 1.00 hour lecture per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.

PracticalWeek: 21 - 31
Thirty six 1.00 hour practical per study period on weekdays during the day from week 21 to week 31 and delivered via face-to-face.
Consisting of wet/dry/simulation activities.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

WorksheetsAround 400 words total

N/AN/AN/ANo14SILO1, SILO3, SILO4, SILO5, SILO6, SILO7

Practical reports (one major, one minor)Major report around 950 words; minor report around 450 words

N/AN/AN/ANo25SILO1, SILO3, SILO4, SILO5, SILO6, SILO7, SILO8

Oral presentation (10 min)A group of four students will give a joint ten minute presentation: equivalent to 1000 words, so 250 words for each student

N/AN/AN/ANo10SILO2, SILO4, SILO5, SILO6, SILO8

On-line quizzes (weeks 2-12)Based on 2015 records, most students took around 5min to complete each quiz, so under an hour in total for all of the quizzes. Therefore this task is equivalent to 1000 words

N/AN/AN/ANo11SILO5, SILO6, SILO7, SILO8

Exam (1.5 hour)Equivalent to 1500 words

N/AN/AN/ANo40SILO5, SILO6, SILO8

Singapore (PSB), 2020, Term 2, Night

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Yeliz Boglev

Class requirements

LectureWeek: 21 - 31
Thirty six 1.00 hour lecture per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.

PracticalWeek: 21 - 31
Thirty six 1.00 hour practical per study period on weekdays at night from week 21 to week 31 and delivered via face-to-face.
Consisting of wet/dry/simulation activities.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

WorksheetsAround 400 words total

N/AN/AN/ANo14SILO1, SILO3, SILO4, SILO5, SILO6, SILO7

Practical reports (one major, one minor)Major report around 950 words; minor report around 450 words

N/AN/AN/ANo25SILO1, SILO3, SILO4, SILO5, SILO6, SILO7, SILO8

Oral presentation (10 min)A group of four students will give a joint ten minute presentation: equivalent to 1000 words, so 250 words for each student

N/AN/AN/ANo10SILO2, SILO4, SILO5, SILO6, SILO8

On-line quizzes (weeks 2-12)Based on 2015 records, most students took around 5min to complete each quiz, so under an hour in total for all of the quizzes. Therefore this task is equivalent to 1000 words

N/AN/AN/ANo11SILO5, SILO6, SILO7, SILO8

Exam (1.5 hour)Equivalent to 1500 words

N/AN/AN/ANo40SILO5, SILO6, SILO8

Singapore (PSB), 2020, Term 3, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Yeliz Boglev

Class requirements

LectureWeek: 37 - 47
Thirty six 1.00 hour lecture per study period on weekdays during the day from week 37 to week 47 and delivered via face-to-face.

PracticalWeek: 37 - 47
Thirty six 1.00 hour practical per study period on weekdays during the day from week 37 to week 47 and delivered via face-to-face.
Consisting of wet/dry/simulation activities.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

WorksheetsAround 400 words total

N/AN/AN/ANo14SILO1, SILO3, SILO4, SILO5, SILO6, SILO7

Practical reports (one major, one minor)Major report around 950 words; minor report around 450 words

N/AN/AN/ANo25SILO1, SILO3, SILO4, SILO5, SILO6, SILO7, SILO8

Oral presentation (10 min)A group of four students will give a joint ten minute presentation: equivalent to 1000 words, so 250 words for each student

N/AN/AN/ANo10SILO2, SILO4, SILO5, SILO6, SILO8

On-line quizzes (weeks 2-12)Based on 2015 records, most students took around 5min to complete each quiz, so under an hour in total for all of the quizzes. Therefore this task is equivalent to 1000 words

N/AN/AN/ANo11SILO5, SILO6, SILO7, SILO8

Exam (1.5 hour)Equivalent to 1500 words

N/AN/AN/ANo40SILO5, SILO6, SILO8

Singapore (PSB), 2020, Term 3, Night

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Yeliz Boglev

Class requirements

LectureWeek: 37 - 47
Thirty six 1.00 hour lecture per study period on weekdays at night from week 37 to week 47 and delivered via face-to-face.

PracticalWeek: 37 - 47
Thirty six 1.00 hour practical per study period on weekdays at night from week 37 to week 47 and delivered via face-to-face.
Consisting of wet/dry/simulation activities.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

WorksheetsAround 400 words total

N/AN/AN/ANo14SILO1, SILO3, SILO4, SILO5, SILO6, SILO7

Practical reports (one major, one minor)Major report around 950 words; minor report around 450 words

N/AN/AN/ANo25SILO1, SILO3, SILO4, SILO5, SILO6, SILO7, SILO8

Oral presentation (10 min)A group of four students will give a joint ten minute presentation: equivalent to 1000 words, so 250 words for each student

N/AN/AN/ANo10SILO2, SILO4, SILO5, SILO6, SILO8

On-line quizzes (weeks 2-12)Based on 2015 records, most students took around 5min to complete each quiz, so under an hour in total for all of the quizzes. Therefore this task is equivalent to 1000 words

N/AN/AN/ANo11SILO5, SILO6, SILO7, SILO8

Exam (1.5 hour)Equivalent to 1500 words

N/AN/AN/ANo40SILO5, SILO6, SILO8