MEDICINAL AND ORGANIC CHEMISTRY

CHE2MOC

2020

Credit points: 15

Subject outline

In this subject you will be introduced to medicinal chemistry, with an emphasis on how drugs interact with their molecular targets of lipids, carbohydrates, nucleic acids and proteins. A key aspect is to develop understanding of organic chemistry, where you will focus on the properties, nomenclature, reactions and mechanisms of key functional groups used in organic synthesis, including the critical concept of stereochemistry. You will gain experience conducting and interpreting laboratory experiments related to the synthesis of organic and molecules with a focus on medicinal drug design.

School: Molecular Sciences (Pre 2022)

Credit points: 15

Subject Co-ordinator: Yuning Hong

Available to Study Abroad/Exchange Students: Yes

Subject year level: Year Level 2 - UG

Available as Elective: No

Learning Activities: N/A

Capstone subject: No

Subject particulars

Subject rules

Prerequisites: CHE1APL AND (CHE1GEN OR CHE1CHF)

Co-requisites: N/A

Incompatible subjects: N/A

Equivalent subjects: N/A

Quota Management Strategy: N/A

Quota-conditions or rules: N/A

Special conditions: N/A

Minimum credit point requirement: N/A

Assumed knowledge: N/A

Learning resources

Organic Chemistry

Resource Type: Book

Resource Requirement: Prescribed

Author: McMurry, J.

Year: 2016

Edition/Volume: N/A

Publisher: Thomson-Brooks/Cole

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Introduction to Medicinal Chemistry

Resource Type: Book

Resource Requirement: Prescribed

Author: Patrick, G.

Year: 2013

Edition/Volume: N/A

Publisher: Oxford University Press

ISBN: N/A

Chapter/article title: N/A

Chapter/issue: N/A

URL: N/A

Other description: N/A

Source location: N/A

Career Ready

Career-focused: No

Work-based learning: No

Self sourced or Uni sourced: N/A

Entire subject or partial subject: N/A

Total hours/days required: N/A

Location of WBL activity (region): N/A

WBL addtional requirements: N/A

Graduate capabilities & intended learning outcomes

Graduate Capabilities

Intended Learning Outcomes

01. Explain the fundamental concepts of medicinal chemistry.
02. Illustrate understanding of the ways drugs interact with their molecular targets.
03. Employ concepts of bonding to explain the properties of organic compounds.
04. Design synthetic schemes for the preparation of organic compounds showing understanding of reaction mechanisms.
05. Demonstrate practical skills needed to conduct chemical synthesis, chemical analysis and be able to interpret and report the results of spectroscopic measurements.

Melbourne (Bundoora), 2020, Semester 1, Day

Overview

Online enrolment: Yes

Maximum enrolment size: N/A

Subject Instance Co-ordinator: Yuning Hong

Class requirements

Laboratory ClassWeek: 10 - 22
One 3.00 hours laboratory class per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.
The laboratory program consists of 6 classes and additional learning activities (3 hours each) over the semester. A schedule of experiments will be made available to students on the LMS at the start of semester.

Laboratory ClassWeek: 11 - 13
One 3.00 hours laboratory class per week on weekdays during the day from week 11 to week 13 and delivered via face-to-face.
The laboratory program consists of 6 classes and additional learning activities (3 hours each) over the semester. A schedule of experiments will be made available to students on the LMS at the start of semester.

LectureWeek: 10 - 22
Two 1.00 hour lecture per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

SeminarWeek: 10 - 10
One 3.00 hours seminar per week on weekdays during the day from week 10 to week 10 and delivered via face-to-face.
Laboratory safety introduction will be held in the first week of semester.

TutorialWeek: 10 - 22
One 1.00 hour tutorial per week on weekdays during the day from week 10 to week 22 and delivered via face-to-face.

Assessments

Assessment elementCommentsCategoryContributionHurdle%ILO*

Online quizzes (500 words equiv)Two LMS quizzes during semester.

N/AN/AN/ANo10SILO1, SILO2

Laboratory work and reports (1500 words equivalent)Hurdle for accreditation with RACI. Students must complete a minimum 75% of lab assessment, and must obtain a score of at least 50% for the laboratory component of the subject.

N/AN/AN/AYes30SILO3, SILO4, SILO5

Test (500 words equivalent)One in class test during semester

N/AN/AN/ANo10SILO3, SILO4

Examinations (2 x 1 hour exams) or equivalent assessment tasks during semesterTwo 1 hour papers in the central examination period or equivalent assessment tasks during semester. Students can select either option.

N/AN/AN/ANo50SILO1, SILO2, SILO3, SILO4