Cardiovascular physiology
Our research activities include developing novel therapies (drugs and other strategies) for cardiovascular disease (especially myocardial infarction, heart failure and diabetes). Functional components of diet to prevent/reverse chronic disease (esp. CVD and diabetes) are also a significant focus of our group (anti-inflammatory and antioxidant mechanisms of action; role of the gut microbiome).
Our routine techniques include
- small and large animal models of CV disease
- clinical trials and studies
- echocardiography (cardiac function) & haemodynamics
- planimetry (computer imaging quantitation of heart infarct size)
- biochemical / hormone / molecular assays
- body composition (DEXA/anthropometry)
- actigraphy (physical activity)
- food diaries; nutrient analysis
- continuous glucose monitoring
- large databases
Current projects
- Novel drugs and strategies to reduce myocardial ischaemia-reperfusion injury
- Gene therapy for heart failure
- AUSMED Heart Trial – Mediterranean Diet intervention in secondary prevention of cardiac events; mechanisms of protection
- Adherence to Med Diet pattern, cognitive function in older people, and potential interactions with cardiovascular health
- The effect of high-polyphenol olive oil on markers of cardiovascular disease risk and cognition
- The microbiome as a cardiometabolic and hypertension target
- Tribal populations (India): emergent lifestyle diseases (esp. CVD/diabetes)
- Effect of diabetes on mental health in women
- Alternatives for standard hospital mid-meals to improve glycaemic control in patients with type 2 diabetes
Team members
Research leader: Dr Colleen Thomas
Masters student: Sophie Skalkos
PhD students: Sebastian Bass-Stringer, Shan Huang, Katerina Sarapis, Sarah Knowler, Flavia Wassel, Mihiri Munasanghe, Suzanne Douglas, Andrea Bramley, Narayan Nair
Honours students: Holly Brettle, Erica Liapis, Johanna Hoskin, Aanchal Dayan
