Gene-environment interactions

We are interested in understanding the role gene-environment interactions in the development of diseases relevant to public health. We are particularly interested in the diet-gene interactions involved in the development of neurological conditions and disorders including depression, dementia and schizophrenia.

Using a novel method of feeding system for the model organism Caenorhabditis elegans that allows precise control of diet, nutrient-gene interactions relevant development of disease and the role of culinary herbs and spices in the prevention and treatment of disease are studied.

Current projects

  • Identification of dietary pattern and food components for the prevention and treatment of Alzheimer’s disease using a novel approach
  • Effects of antidepressants and antipsychotics on lifespan and insulin sensitivity in C. elegans.
  • Effects of culinary herbs and spices on body composition of patients treated with antidepressants and antipsychotic medications
  • Role of polyphenols in the prevention and treatment of Alzheimer’s disease C. elegans.
  • Effects of natural and artificial sweeteners on body composition and insulin sensitivity

Team members

Group leaders: Dr Mark Jois and Dr Jency Thomas

PhD students: Munagamage Dona Mihiri Munasinghe, Abdullah Mohammed Almotayri

Honours students: Despina Kovalis, Selin Ramadan