CYP 450 polymorphisms in patients being treated for serious illnesses

It is known that people who carry certain genetic markers are less capable of coping with various medicines. These people may experience some profound side effects, which may mean that they stop taking their medicines, with negative outcomes.

In this project we are assessing patients being treated for serious illnesses in hospitals to see if they carry any genetic markers that may impact upon their capacity to cope with their drug therapy. This study may help personalise their drug doses, so that they are less likely to suffer serious side effects, and get more benefit from their medication.