Recent publications


Yaakob NS, Nguyen D, Exintaris B and Irving HR (2018) The C and E subunits of the serotonin 5-HT3 receptor subtly modulate the electrical properties of the receptor, Biomedicine and Pharmacotherapy, 97: 1701-1709.

Marondedze C, Wong A, Thomas L, Irving H and Gehring C (2017) Cyclic nucleotide monophosphates in plants and plant signalling, in “Non-canonical Cyclic Nucleotides” part of “The Handbook of Experimental Pharmacology (HEP)” series, Volume 238 (editor R. Seifert), pp 87-103.

Wheeler JI, Wong A, Marondedze C, Groen AJ, Kwezi L, Freihat L, Vyas J, Raji MR, Irving HR and Gehring C (2017) The brassinosteroid receptor BRI1 can generate cGMP enabling cGMP-dependent downstream signalling, Plant J., 91(4): 590-600.

Murphy NM, Pouton CW and Irving HR (2017) High molecular weight DNA enriched with peptide nucleic acid probes, Methods Mol Biol., 1551: 75-85.

Muleya V, Marondedze C, Wheeler JI, Thomas L, Mok Y-F, Griffin MDW, Manallack DT, Kwezi L, Lilley KS, Gehring C and Irving HR (2016) Phosphorylation of the dimeric cytoplasmic domain of the phytosulfokine receptor, PSKR1, Biochem J., 473(19): 3081-98.

Murphy NM, Burton M, Powell D, Rossello F, Cooper D, Chopra A, Hsieh M, Sayer D, Gordon L, Pertile M, Tait BD, Irving HR and Pouton CW (2016) Haplotyping the human leukocyte antigen system from single chromosomes, Sci Rep., 6: 30381.

Muleya V and Irving HR (2016) Delineating a new class of membrane-bound guanylate cyclases, Springer Sci Rev., 4: 1-13.

Turek I, Wheeler J, Gehring C, Irving HR and Marondedze C (2015) Quantitative proteome changes in Arabidopsis thaliana suspension-cultured cells in response to plant natriuretic peptides, Data Brief., 4: 336-43.

Wong A, Gehring C and Irving HR (2015) Conserved functional motifs and homology modelling to predict hidden moonlighting functional sites, Front Bioeng Biotechnol., 3: 82.

Yaakob NS, Chinkwo KA, Chetty N, Coupar IM and Irving HR (2015) Distribution of 5-HT3, 5-HT4 and 5-HT7 receptors along the human colon, J Neurogastroenterol Mot., 21: 361-369.

Turek I, Marondedze C, Wheeler J, Gehring C and Irving H (2014) Plant Natriuretic Peptides induce proteins diagnostic for an adaptive response to stress, Front Plant Sci., 5: 661.

Freihat L, Muleya V, Manallack DT, Wheeler JI and Irving HR (2014) Comparison of moonlighting guanylate cyclases – roles in signal direction?, Biochem Soc Trans., 42: 1773-79.

Muleya V, Wheeler JI, Ruzvidzo O, Freihat L, Manallack DT, Gehring C and Irving HR (2014) Calcium is the switch in the moonlighting dual function of the ligand-activated receptor kinase phytosulfokine receptor 1, Cell Commun Signal., 12: 60.

Murphy NM, Pouton CW and Irving HR (2014) Human leukocyte antigen haplotype phasing by allele-specific enrichment with peptide nucleic acid probes, Mol Genet Genomic Med., 2: 245-53.

Gehring C and Irving H (2013) Plant Natriuretic Peptides: systemic regulators of plant homeostasis and defense that can affect cardiomyoblasts, J Invest Med., 61: 823-26.

Irving H and Gehring C (2013) Molecular methods for the study of signal transduction in plants, Methods Mol Biol., 1016: 1-11.

Mellor JD, Brown MP, Irving HR, Zalcberg JR and Dobrovic A (2013) A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer, J Hematol Oncol., 6: 1.

Muleya V, Wheeler JI and Irving HR (2013) Structural and functional characterization of receptor kinases with nucleotide cyclase activity, Methods Mol Biol., 1016: 175-94.

Wheeler JI, Freihat L and Irving HR (2013) A cyclic nucleotide sensitive promoter reporter system suitable for bacteria and plant cells, BMC Biotech., 13: 97.

Coupar IM, Irving HR, Manallack DT, Tan YY, Ayad F, Di Iulio J, Tochon-Danguy N and Iskander MN (2012) Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors, J Pharm Pharmacol., 64: 1099-1106.

Irving HR, Kwezi L, Wheeler JI and Gehring C (2012) Moonlighting kinases with guanylate cyclase activity can tune regulatory signal networks, Plant Signal Behav., 7: 201-04.

Kwezi L, Ruzvidzo O, Wheeler JI, Govender K, Iacuone S, Thompson PE, Gehring C and Irving HR (2011) The phytosulfokine (PSK) receptor is capable of guanylate cyclase activity and enabling cyclic GMP-dependent signaling in plants, J Biol Chem., 286: 22580-88.

Nedi T, White PJ, Coupar IM and Irving HR (2011) Tissue dependent differences in G-protein coupled receptor kinases associated with 5‑HT4 receptor desensitization in the rat gastro-intestinal tract, Biochem Pharmacol., 81: 123-33.

Wang YH and Irving HR (2011) Developing a model of plant hormone interactions, Plant Signal Behav., 6: 494-500.

Wang YH, Donaldson L, Gehring C and Irving HR (2011) Plant natriuretic peptides: control of synthesis and systemic effects, Plant Signal Behav., 6: 1606-1608.

Wang YH, Gehring C and Irving HR (2011) Plant Natriuretic Peptides are apoplastic and paracrine stress response molecules, Plant Cell Physiol., 52: 837-50.

Yaakob N, Malone DT, Exintaris B and Irving HR (2011) Heterogeneity amongst 5‑HT3 receptor subunits: is this significant? Curr Mol Med., 11: 57-68.