Saifuzzaman M, Morrison R, Zheng Z, Orive S, Hamilton J, Thompson P and Al-Rawi J (2017) Synthesis and biological evaluation of 8-aryl-2-morpholino-7-O substituted benzo[e][1,3]oxazin-4-ones against DNA-PK, PI3K, PDE3A enzymes and platelet aggregation, Bioorganic & Medicinal Chemistry, 25(20): 5531-5536.
Radhamani S, Suraj R, Meehan-Andrews TT, Al-Rawi J and Bradley C (2017) Radiosensitizing activity of novel small molecule BRCA1 and DNA-PKinhibitors in lung and colon carcinoma, Journal of Radiation Research and Applied Sciences, 10(3): 204-213, doi.org/10.1016/j.jrras.2017.04.008.
Heppell JT and Al-Rawi JMA (2016) Synthesis, structures elucidation, DNA-PK, PI3K and antiplatelet activity of a series of novel 7, or 8-(N-substituted)-2-morpholino-quinazolines, Med Chem Res., 25(8): 1695-1704.
Morrison R and Al-Rawi JMA (2016) Synthesis, structure elucidation, DNA-PK, PI3K, anti-platelet and anti-bacteria activity of linear 5, 6, and 10-substituted-2-morpholino-chromen-oxazine-dione and angular 3, 4, 6-substituted-8-morpholino-chromen-oxazine-2,10-dione, J Enzyme Inhib Med Chem., 31(sup 2): 86-95.
Morrison R, Zheng Z, Jennings IG, Thompson PE and Al-Rawi JMA (2016) Synthesis of linear and angular aryl-morpholino-naphth-oxazines, their DNA-PK, PI3K, PDE3A and antiplatelet activity, Bioorg Med Chem Lett., 26(22): 5534-38.
Morrison R, Al-Rawi JM, Jennings IG, Thompson PE and Angove MJ (2016) Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines, Eur J Med Chem., 110: 326-39.
Heppell JT and Al-Rawi JMA (2015) Synthesis, antibacterial, and DNA-PK evaluation of some novel 6-fluoro-7-(cyclic amino)-2-(thioxo or oxo)-3-substituted quinazolin-4-ones as structural analogues of quinolone and quinazolin-2,4-dione antibiotics, Med Chem Res., 24(6): 2756-69.
Heppell J and Al-Rawi J (2015) Functionalisation of quinazolin-4-ones Part 2#: reactivity of 2 amino-3, 4, 5, or 6-nitrobenzoic acids with triphenylphosphine thiocyanate, alkylisothiocyanates, and further derivatization reactions, J Heterocyclic Chem., 52(5): 1361-67.
Ihmaid SK, Fitzgibbon C and Al-Rawi JMA (2015) Synthesis, toxicity and chemo-sensitization of HeLa cells to etoposide, of some 2-methyl amino acid ester-substituted-1,3-benzoxazines, Med Chem Res., 24: 2825-37.
Al-Rawi S, Meehan-Andrews T, Bradley C and Al-Rawi J (2014) Novel benzoxazines as inhibitors of angiogenesis, Invest New Drugs, 33(1): 45-52.
Morrison R, Belz T, Ihmaid SK, Al-Rawi JMA and Angove MJ (2014) Dual and/or selective DNA-PK, PI3K inhibition and isoform selectivity of some new and known 2-amino-substituted-1,3-benzoxazines and substituted-1,3-naphthoxazines, Med Chem Res., 23(11): 4680-91.
Belz T, Ihmaid S, Al-Rawi J and Petrovski S (2013) Synthesis characterization and anti-bacterial, anti-fungal activity of N-(benzyl carbamoyl or carbamothioyl)-2-hydroxy substituted benzamide and 2-benzyl amino-substituted-benzoxazines, Int J Medic Chem., 2013: 436397.
Radhamani S, Bradley C, Meehan-Andrews T, Ihmaid SK, Al-Rawi JMA and Angove MJ (2014) Radiosensitizing activity of selected substituted Benzoxazines through the promotion of apoptosis and inhibition of DNA repair, Invest New Drugs, 32(3): 424-35.
Fitzgibbon C, Ihmaid S, Al-Rawi J, Meehan-Andrews T and Bradley C (2013) Chemo-sensitisation of HeLa cells to Etoposide by a Benzoxazine in the absence of DNA-PK inhibition, Invest New Drugs, 31(6): 1466-75.
Ihmaid SK, Al-Rawi JMA, Bradley CJ, Angove MJ and Robertson MN (2012) Synthesis, DNA-PK inhibition, anti-platelet activity studies of 2-(N-substituted-3-aminopyridine)-substituted-1,3-benzoxazines and DNA-PK and PI3K inhibition, homology modelling studies of 2-morpholino-(7, 8-di and 8-substituted)-1,3-benzoxazines, Eur J Med Chem., 57: 85-101.
Heppell J and Al-Rawi J (2014) Functionalisation of Quinazolin-4-ones part 1: synthesis of novel 7-substituted-2-thioxo -quinazolin-4-ones from 4-substituted-2-aminobenzoic acids and PPh3(SCN)2,, J Heterocyclic Chem., 51: 162-74.
McKerrow JD, Al-Rawi JMA and Brooks P (2012) Synthesis of some N-Aryl α-amino acids using diaryliodonium salts, Asian J Chem., 24(3): 1227-36.
Ihmaid S, Al-Rawi J, Bradley C, Angove MJ, Robertson MN and Clark RL (2011) Synthesis, structural elucidation, DNA-PK inhibition, homology modeling and anti-platelet activity of morpholino-substituted-1,3-naphth-oxazines, Bioorg Med Chem., 19(13): 3983-94.