The University features in the top 100 global universities in history (ranking at number 6 nationally), sociology (7th nationally), and communication and media studies (9th nationally).
Seven La Trobe subjects are in the world's top 200 list: linguistics, agriculture, psychology, accounting and finance, education, law, politics and international studies.
For English language and literature, the University ranks in the top 300, while computer science and Information systems as well as biological sciences also made the top 400 list.
The QS rankings evaluate 3,500 of the world's 8,000 research and teaching universities in 14,000 programs across 36 subject groups. They are based on academic and employer reputation and research impact.
Vice-Chancellor Professor John Dewar said this was an extremely pleasing result.
He said the rankings demonstrated La Trobe's continuing success as world-class university.
'These results are a testament to the efforts and energy of academic staff in delivering high-quality teaching and cutting-edge ideas and research outcomes for the benefit of students, employers and wider society,' he said.
The latest Times Higher Education World University Subject Rankings also saw La Trobe among the top 100 universities in the arts and humanities, at number 99.
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