Bruce Stone Fellow in Chemical Biology

Dr David Greening

Dr David Greening is a Bruce Stone Fellow in Chemical Biology.

Dr Greening completed his PhD at The University of Melbourne, focusing on quantitative proteomics and understanding the cancer secretome – specifically tumour-derived peptides and their function. He was a postdoctoral fellow at the Ludwig Institute for Cancer Research and received further training in quantitative proteomics at the Institute for Systems Biology (USA), before moving to LIMS in 2011.

Dr Greening has 53 publications (23 first author, 19 corresponding/senior author, >2400 citations). He has discovered novel methods for production, isolation, and purification of extracellular vesicles (exosomes), which are regarded as standard practice in extracellular biology and cell communication. He has investigated the functional characterisation of the cancer secretome, defining mechanisms promoting tumorigenesis, and regulating angiogenesis.

Dr Greening’s work also encompasses uterine biology, and has important implications for research into novel interventions designed to reduce infertility and establish a successful pregnancy.

For further information on Dr David Greening's research, visit his lab page.

Dr Donna Whelan

Dr Donna Whelan is a Bruce Stone Fellow in Chemical Biology.

Dr Whelan completed her PhD at Monash University, developing advanced microscopic and spectroscopic techniques for applications in biophysical research. During her PhD she constructed cutting-edge single molecule super-resolution microscopes and made extensive use of the Australian Synchrotron. She was a postdoctoral fellow at New York University’s School of Medicine under the supervision of Dr Eli Rothenberg, focussing on applying super resolution imaging to map the cellular repair pathway of DNA double strand breaks.

Dr Whelan joined LIMS in 2018. Based at the Bendigo campus, she is currently building a new, next-generation single molecule microscope, and exploring DNA damage and repair pathways. Her collaborations include research into the underlying mechanisms of host-virus interactions, neurodegeneration, and proteolysis.

Dr Whelan has 17 publications (11 first author) including in leading interdisciplinary and specialist journals (Nature Communications, Nucleic Acids Research, Journal of Physical Chemistry Letters). She prides herself on taking an active and conscientious role in the mentoring of undergraduate and PhD students, and in communicating science and its importance to the wider community. She has spoken at over 25 national and international conferences and has been awarded more than a dozen prizes and grants including the Vice Chancellor’s Commendation for Doctoral Thesis Excellence and the Stephen Wilkins Thesis Medal.

For further information on Dr Donna Whelan's research, visit her lab page.