Publications

For a complete list of publications see:
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Petrie EJ, Sandow JJ, Jacobsen AV, Smith BJ, Griffin MDW, Lucet IS, Dai W, Young SN, Tanzer MC, Wardak A, Liang L-Y, Cowan AD, Hildebrand JM, Kersten WJA, Lessene G, Silke J, Czabotar PE, Webb AI and Murphy JM (2018) Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis, Nature Communications, 9.

Meftahi N, Walker ML, Enciso M and Smith BJ (2018) Predicting the Enthalpy and Gibbs Energy of Sublimation by QSPR Modeling, Scientific Reports, 8.

Smedley CJ, Stanley PA, Qazzaz M, Prota AE, Olieric N, Collins H, Eastman H, Barrow A, Lim K, Kam T, Smith B, Duivenvoorden HM, Parker BS, Bradshaw TD, Steinmetz M and Moses J (2018) Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site, Scientific Reports, 8(1): 10617.

Gruszczyk J, Kanjee U, Chan LJ, Menant S, Malleret B, Lim NTY, Schmidt CQ, Mok YF, Lin KM, Pearson RD, Rangel G, Smith BJ, Call MJ, Weekes MP, Griffin MDW, Murphy JM, Abraham J, Sriprawat K, Menezes MJ, Ferreira MU, Russell B, Renia L, Duraisingh MT and Tham WH (2018) Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax, Science, 359(6371): 48-55.

Glidden MD, Yang Y, Smith NA, Phillips NB, Carr K, Wickramasinghe NP, Ismail-Beigi F, Lawrence MC, Smith BJ and Weiss MA (2018) Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding, The Journal of Biological Chemistry, 293: 69-88.

Weiss MA, Phillips NF, Ismail-Beigi F, Pandyarajan V, Yang W, Chen YS, Wickramasinghe N, Smith B, Menting JG, Lawrence MC, El-Hage K and Meuwly M (2017) Non-Standard Protein Engineering at the Boundary of Molecular Mechanics and Quantum Chemistry: Halogen-Based Design of Insulin Analogs, Biophysical Journal, 112(3): 53a.

Brouwer JM, Lan P, Cowan AD, Bernardini JP, Birkinshaw RW, van Delft MF, Sleebs BE, Robin AY, Wardak A, Tan IK, Reljic B, Lee EF, Fairlie WD, Call MJ, Smith BJ, Dewson G, Lessene G, Colman PM and Czabotar PE (2017) Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design, Mol Cell., 68(4): 659-672.e9, doi: 10.1016/j.molcel.2017.11.001.

Johnson S, Rahmani R, Drew DR, Williams MJ, Wilkinson M, Tan YH, Huang JX, Tonkin CJ, Neeson JG, Baum J, Smith BJ* and Baell JB (2016) Truncated latrunculins as actin inhibitors targeting plasmodium falciparum motility and host cell invasion, J. Med. Chem., 59: 10994-11005.

El Hage K, Pandyrarajan V, Phillips NB, Smith BJ, Menting JG, Whittaker J, Lawrence MC, Meuwly M and Weiss MA (2016) Extending halogen-based medicinal chemistry to proteins: Iodo-insulin as a case study, J. Biol. Chem., 291: 27023-27041.

Shahmiri M, Enciso M, Adda CG, Smith BJ, Perugini MA and Mechler A (2016) Membrane core-specific antimicrobial action of cathelicidon LL-37 peptide switches between pore and nanofibre formation, Sci. Rep., 6: 38184.

Enciso M, Meftahi N, Walker ML and Smith BJ (2016) BioPPSy: an open-source platform for QSAR/QSPR analysis, PLoS One., 11: e0166298.

Menting JG, Gajewaik J, MacRaild CA, Chou DH, Disotuar M, Smith NA, Miller C, Echegyi J, Rivier JE, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H and Lawrence MC (2016) A minimized human insulin receptor binding motif is revealed in a venom insulin, Nat. Struct. Mol. Biol., 23: 916-20.

Lawrence CF, Margets MB, Meeting JG, Smith NA, Smith BJ, Ward CW and Lawrence MC (2016) Insulin mimetic peptide disrupts the primary binding site of the insulin receptor, J. Biol. Chem., 291: 15473-81.

Lee EF, Grabow S, Chappaz S, Dewson G, Hockings C, Kluck RM, Gray DH, Witkowski MT, Evangelista M, Pettikiriarachchi A, Bouillet P, Lane RM, Czabotar PE, Colman PM, Smith BJ, Kile BT and Fairlie WD (2016) Physiological restraint of Bak by Bcl-xL is essential for cell survival, Genes Devel., 30: 1240-50.

Iyer S, Anwari K, Alsop AE, Yuen WS, Carroll J, Huang DCS, Smith NA, Smith BJ, Dewson G and Kluck RM (2016) Discovery of an activation site in Bak and mitochondrial Bax triggered by antibodies, Nat. Commun., 7: 11734.

Croll TI, Smith BJ, Margets MB, Whittaker J, Weiss MA, Ward CW and Lawrence MC (2016) Higher-resolution structure of the human insulin receptor ectodomain: multi-modal inclusion of the insert domain, Structure, 24(3): 469-76.

Seoudi RS, Dowd A, Smith BJ and Mechler A (2016) Structural analysis of bioinspired nano-materials with synchrotron Far-IR spectroscopy, Phys Chem Chem Phys., 18: 11467-75.

Coffey MJ, Sleebs BE, Uboldi AD,Garnham A, Franco M, Marino ND, Panas M, Ferguson DLP, Enciso M, O'Neill MT, Lopaticki S, Stewart RJ, Dewson G, Smyth GK, Smith BJ, Masters SL, Boothroyd JC, Boddey JA and Tonkin CJ (2015) An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell, eLife, e10809.

Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, Eller CH, Raines RT, Murphy WL, Smith BJ, Gellman SH and Fairlie WD (2015) a/b-peptide foldamers targeting intracellular protein-protein interactions with activity in living cells, J. Am. Chem. Soc., 137(35): 11365-75.

Williams MJ, Alonso H, Enciso M, Egarter S, Shiener L, Meissner M, Striepen B, Smith BJ and Tonkin CJ (2015) Two essential light chains regulate MyoA lever arm to promote gliding motility in Toxoplasma gliding motility, MBio, 6(5): e00845-15.

Hodder AN, Sleebs BE, Czabotar PE, Gazdik M, Xu Y, O'Neill MT, Lopaticki S, Nebl T, Triglia T, Smith BJ, Lowes K, Boddey JA and Cowman AF (2015) Structural basis for plasmepsin V activity and inhibition that blocks export of malaria proteins to the host cell, Nat. Struct. Mol. Biol., 22: 590-96.

Chang SC, Huq R, Chhabra S, Beeton C, Pennington M, Smith BJ and Norton R (2015) N-terminally extended analogues of the K+ channel toxin from Stichodatyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3., FEBS J., 282(12): 2247-59.

Iyer S, Bell F, Westphal D, Anwari K, Gulbis JM, Smith BJ, Dewson G and Kluck R (2015) Bak and Bax apoptotic pores involve juxtaposition of the C-terminal transmembrane domains, Cell Death Differ., 22(10): 1665-75.

Gazdik M, O'Neil MT, Lopaticki S, Lowes KN, Smith BJ, Cowman AF, Boddey JA and Sleebs BE (2015) The effect of N-methylation on transition state mimetic inhibitors of the Plasmodium protease, plasmepsin V., MedChemComm, 6: 437-43.