Publications

Recent publications

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Publications

Post 2016

Gao B, Li S, Wu P, Moses JE and Sharpless KB (2018) SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides and Sulfonimidates, Angew. Chem. Int Ed., DOI: 10.1002/anie.201712145.

Jenner M, Kosol S, Griffiths D, Prasongpholchai P, Manzi L, Barrow AS, Moses JE, Oldham NJ, Lewandowski JR and Challis GL (2018) Mechanism of Subunit Interaction at Ketosynthase-Dehydratase Junctions in trans-AT Polyketide Synthases, Nat. Chem. Biol., doi: 10.1038/nchembio.2549.

Manzi L, Barrow AS, Hopper JTS, Kaminska R, Kleanthous C, Robinson CV, Moses JE* and Oldham NJ* (2017) Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein, Angew. Chem. Int. Ed., 56(47): 14873.

Smedley CJ, Barrow AS, Spiteri C, Giel M, Sharma P and Moses JE (2017) Sulfur-Fluoride Exchange (SuFEx)-Mediated Synthesis of Sterically Hindered and Electron-Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates, Chem. Eur. J., 23(42): 9990-5.

Li S, Wu P, Moses JE and Sharpless KB (2017) Thionyl tetrafluoride (O=SF4) adds another dimension to SuFEx click chemistry: A S-(VI)-Hub, which sequentially and flawlessly accepts three discreet, SuFEx-able modules, Angew Chem Int Ed., 56(11): 2903-2908.

Han L-C, Stanley PA, Wood P, Bradshaw TD and Moses JE (2016) Horner–Wadsworth–Emmons approach to piperlongumine analogues with potent anti-cancer activity, Org Biomol Chem., 14: 7585.

Silverman SM, Sharpless KB and Moses JE (2016) Click chemistry synthesis of [1,2,3]-triazole vancomycin dimers with potent activity against MRSA and VRE, Chem Eur J, 23: 79.

Manzi L, Barrow AS,Scott D, Layfield R, Wright TG, Moses JE and Oldham NJ (2016) Carbene footprinting accurately maps binding sites in protein-ligand and protein-protein interactions, Nat Commun., 7: 13288.

Zhang E, Tang J, Li S, Wu P, Moses JE and Sharpless KB (2016) Chemoselective synthesis of polysubstituted pyridines from heteroaryl fluorosulfates, Chem Eur J, 22: 5692.

Barrow AS and Moses JE (2016) Synthesis of sulfonyl azides via Lewis Base Activation of sulfonyl fluorides and trimethylsilyl azide, Synlett, 27: 1840.

Bhat SV, Robinson D, Sharma P and Moses JE (2016), Synthesis of oxadiazol-5-imines via the cyclizative capture of in situ generated cyanamide ions and nitrile oxides, Org Lett., 18: 1100.

Stanley PA, Spiteri C, Moore JC, Barrow AS, Sharma P and Moses JE (2016) Biomimetic approaches towards the synthesis of complex dimeric natural products, Curr Pharm Des., 22: 1628.

Pre 2016

Roe S, Gunaratnam M, Spiteri C, Sharma P, Alharthy RD, Neidle S and Moses JE (2015) Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors, Org Biomol Chem., 13: 8500.

Cousins ARO, Ritson D, Sharma P, Stevens MFG, Searle MF and Moses JE (2014) Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences, Chem Commun., 50: 15202.

Moore JC, Davies ES, Walsh DA, Sharma P and Moses JE (2014) Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels–Alder reaction, Chem Commun., 50: 12523.

Powell KJ, Han L-C, Sharma P and Moses JE (2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides, Org Lett.,16: 2158.

Dempster S, Harper S, Moses JE and Dreveny I (2014) Structural characterisation of the apo-form and NADH binary complex of human lactate dehydrogenase, Acta Crystallographica Section D, 70: 1484.

Borreguero AM, Carmona MS, Sharma P, Spiteri C, Martínez-Velencoso M, Rodríguez JF and Moses JE (2013) A novel click-chemistry approach to flame retardant polyurethanes, React Funct Polym., 73: 1207.

Carbone G, Burnley J and Moses JE (2013) A catalytic and tert-butoxide ion-mediated amidation of aldehydes with para-nitro azides, Chem Commun., 49: 2759.

Burnley J, Carbone G and Moses JE (2013) Catalytic reduction of ortho- and para-Azidonitrobenzenes via tert-Butoxide ion mediated electron transfer, Synlett, 24: 652.

Powell KJ, Sharma P, Richens JL, Davis BM, O’Shea P and Moses JE (2012) Interactions of marine-derived gamma-pyrone natural products with phospholipid membranes, Phys Chem Chem Phys, 14: 14489.

Ritson DJ and Moses JE (2012) A fragment based click chemistry approach towards hybrid G-quadruplex ligands: design, synthesis and biophysical evaluation, Tetrahedron, 7: 197.

Spiteri C and Moses JE (2012) Continuous flow synthesis of secondary amides by tandem azidation-amidation of anilines, Synlett, 23: 1546.