For a complete list of publications see:

Zoranovic T, Manent J, Willoughby L, Matos de Simoes R, La Marca JE, Golenkina S, Cuiping X, Gruber S, Angjeli B, Kanitz E, Cronin SJF, Neely GG, Wernitzig A, Humbert PO, Simpson K, Mitsiades CS, Richardson HE* and Penninger JM* (2018) A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer, PLoS Genet, 14(10): e1007688.

Portela M, Yang L, Paul S, Li X, Veraksa A, Parsons LM and Richardson HE (2018) Lgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex, Sci Signal, 11(533), doi: 10.1126/scisignal.aar1976.

Poon CLC, Brumby AM and Richardson HE (2018) Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue, Int J Mol Sci, 19(6), doi: 10.3390/ijms19061585.

Ma X, Guo X, Richardson HE, Xu T and Xue L (2018) POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation, Proc Natl Acad Sci USA, 115(9): 2150-2155.

Caria S, Magtoto CM, Samiei T, Portela M, Lim KYB, How JY, Stewart BZ, Humbert PO, Richardson HE and Kvansakul M (2018) Drosophila melanogaster Guk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large, J Biol Chem, 293(12): 4519-4531.

Roesley SNA, La Marca JE, Deans AJ, Mckenzie L, Suryadinata R, Burke P, Portela M, Wang H, Bernard O, Sarcevic B and Richardson HE (2018) Phosphorylation of Drosophila Brahma on CDK-phosphorylation sites is important for cell cycle regulation and differentiation, Cell Cycle, doi: 10.1080/15384101.2018.1493414.

Richardson HE and Portela M (2018) Modelling cooperative tumourigenesis in Drosophila, Bio Med Research Int., doi: 10.1155/2018/4258387.

Stephens R, Lim K, Portela M, Kvansakul M, Humbert P and Richardson HE (2018) The Scribble cell polarity module in the regulation of cell signalling in tissue development and tumourigenesis, J Mol Biol., doi: 10.1016/j.jmb.2018.01.011.

Daniel SG, Russ AD, Guthridge KM, Raina AI, Estes PS, Parsons LM, Richardson HE, Schroeder JA and Zarnescu DC (2018) miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila, Biology Open, 7(1), doi: 10.1242/bio.027391.

Parsons LM, Grzeschik NA, Amaratunga K, Burke P, Quinn LM and Richardson HE (2017) A kinome RNAi screen in drosophila identifies novel genes interacting with Lgl, aPKC and Crb cell polarity genes in epithelial tissues, G3, 8(1), doi: org/10.1534/g3.117.043513.

Willoughby LF, Manent J, Allan K, Lee H, Portela M, Wiede F, Warr C, Meng T-C, Tiganis T and Richardson HE (2017) Differential regulation of protein tyrosine kinase signaling by Dock and the PTP61F variants, FEBS J., 284(14): 2231-2250.

Manent J, Banerjee S, de Matos Simoes R, Zoranovic T, Mitsiades C, Penninger JM, Simpson KJ, Humbert PO and Richardson HE (2017) Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species, Oncogene, doi: 10.1038/onc.2017.175.

Manent J, Banerjee S, de Matos Simoes R, Zoranovic T, Mitsiades C, Penninger JM, Simpson KJ, Humbert PO and Richardson HE (2017) Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species, Oncogene, 36(40): 5658-5660, doi: 10.1038/onc.2017.239. Correction.

Richardson HE and Portela M (2017) Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway, Curr Opin Cell Biol., 48: 1-9, doi: 10.1016/

Richardson H and Portela M (2016) Robo-enabled tumor cell extrusion, Dev Cell, 39(6): 629-31.

Dominado N, La Marca JE, Siddall NA, Heaney J, Tran M, Cai Y, Yu F, Wang H, Somers WG, Quinn LM and Hime GR (2016) Rbf regulates Drosophila Spermatogenesis via control of somatic stem and progenitor cell fate in the larval testis, Stem Cell Rep., 7(6): 1152-63.

Doggett K, Turkel N, Willoughby L, Ellul J, Murray M, Richardson HE and Brumby AM (2015) BTB-Zinc finger oncogenes are required for Ras and Notch-driven tumorigenesis, PLoS One, 10(7): e0132987.

Turkel N, Portela M, Poon C, Li J, Brumby AM and Richardson HE (2015) Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumourigenesis, Biol Open, 4(8): 1024-39.

Portela M, Parsons LM, Grzeschik NA and Richardson HE (2015) Regulation of Notch signalling and endocytosis by the Lgl neoplastic tumor suppressor, Cell Cycle, 14(10): 1496-506.

Richardson HE (2015) Drosophila models of cancer, AIMS Genetics, 2(1): 97-103.

Humbert, PO, Russell SM, Smith L and Richardson HE (2015) The Scribble-Dlg-Lgl module in cell polarity regulation, in Ebnet K, ed., Cell Polarity 1: Biological Role and Basic Mechanisms (Springer), 65-111.

Richardson HE, Willoughby L and Humbert PO (2015) Screening for anti-cancer drugs, Drosophila Encyclopedia of Life Sciences (eLS Wiley), doi:101002/976047001590a0022535.

Richardson HE (2014) Research on the fly, Int Innov., 143: 23-25.

Koe CT, Li S, Rossi F, Wong JJL, Wang Y, Zhang Z, Richardson HE, Robson P, Sung WK, Yu F, Gonzalez C and Wang H (2014) The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages, Elife, 3: e01906.

Parsons LM, Grzeschik NA and Richardson HE (2014) lgl regulates the Hippo pathway independently of Fat/Dachs, Kibra/Expanded/Merlin and dRASSF/dSTRIPAK, Cancers (Basel), 6(2): 879-96.

Parsons LM, Portela M, Grzeschik NA and Richardson HE (2014) Lgl regulates Notch signaling via endocytosis, independently of the apical aPKC-Par6-Baz polarity complex, Curr Biol., 24(18): 2073-84.

Willoughby L, Schlosser T, Manning S, Parisot J, Street I, Richardson HE, Humbert P and Brumby AM  (2013) An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery, Dis Model Mech., 6(2): 521-29.

Khoo P, Allan K, Willoughby L, Brumby AM and Richardson HE (2013) In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin II and JNK signalling, Dis Model Mech., 6(3): 661-78.

Cheng, L, Parsons, LM and Richardson HE (2013) Modelling cancer in Drosophila—The next generation (version 20) Encyclopedia Life Sciences (eLS Wiley), doi: 10.1002/9780470015902.a0020862.pub2.

Portela M and Richardson HE (2013) Death takes a holiday—non-apoptotic role for caspases in cell migration and invasion, Embo Rep, 14(2): 107-08.

Turkel N, Sahota VK, Bolden JE, Goulding KR, Doggett K, Willoughby LF, Blanco E, Martin-Blanco E,  Corominas M, Ellul J, Aigaki T, Richardson HE* and Brumby AM* (2013) The BTB-Zn finger transcription factor Abrupt promotes epithelial neoplasia in Drosophila through maintaining a progenitor cell fate, PLoS Genetics, 9(7): e1003627.

*Contributed equally to work.