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Lee EF, Smith NA, Soares da Costa TP, Meftahi N, Yao S, Harris TJ, Tran S, Pettikiriarachchi A, Perugini MA, Keizer DW, Evangelista M, Smith BJ and Fairlie WD (2019) Structural insights into bcl-2 pro-survival protein interactions with the key autophagy regulator Beclin 1 following phosphorylation by Mst1, Autophagy, doi: 10.1080/15548627.2018.1564557.

North A, Wahlgren WY, Remus D M, Scalise M, Kessans SA, Dunevall E, Claesson E, Soares da Costa TP, Perugini MA, Ramaswamy S, Allison JM, Indiveri C, Friemann R and Dobson RCJ (2018) The sodium sialic acid symporter from Staphylococcus aureus has altered substrate specificity, Front Chem., 6: 233.

Woodcock JM, Goodwin K., Sandow JJ, Coolen C, Perugini MA, Webb AI, Pitson SM, Lopez AF and Carver JA (2018) Role of salt bridges in the dimer interface of 14-3-3ζ in dimer dynamics, N-terminal α-helical order and molecular chaperone activity, J. Biol. Chem., 293: 89-99.

Soares da Costa TP, Abbott BM, Gendall AR, Panjikar S and Perugini MA (2018) Molecular evolution of an oligomeric biocatalyst functioning in lysine biosynthesis, Biophys Rev., 10: 153-162.

Desbois S, John UP and Perugini MA (2018) Dihydrodipicolinate synthase is absent in fungi, Biochimie, 152: 73-84.

Atkinson SC, Dogovski C, Wood K, Griffin MDW, Gorman MA, Hor L, Reboul CF, Buckle AM, Wuttke J, Parker MW, Dobson RCJ and Perugini MA (2018) Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target, Structure, 26(7): 948-959.e5.

Gupta R, Hogan CJ, Perugini MA and Soares da Costa TP (2018) Characterization of recombinant dihydrodipicolinate synthase from the bread wheat Triticum aestivum, Planta, doi: 10.1007/s00425-018-2894-x.

Huang J, Casas Garcia GP, Perugini MA, Fox AH, Bond CS and Lee M (2018) Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins, J Biol Chem, 293(17): 6593-6602.

Gupta R, Soares da Costa TP, Faou P, Dogovski C and Perugini MA (2018) Comparison of untagged and his-tagged dihydrodipicolinate synthase from the enteric pathogen Vibrio cholerae, Protein Expr Purif, 145: 85-93.

Edgar RJ, Hampton GE, Garcia PC, Maher MJ, Perugini MA, Ackerley DF and Lamont IL (2017) Integrated activities of two alternative sigma factors coordinate iron acquisition and uptake by Pseudomonas aeruginosa, Mol. Microbiol., 106(6): 891-904.

Soares da Costa TP, Patel M, Desbois S, Gupta R, Faou P and Perugini MA (2017) Identification of a dimeric KDG aldolase from Agrobacterium tumefaciens, Proteins, 85(11): 2058-2065.

Ellisdon AM, Nold-Petry CA, D’Andrea L, Cho SX, Lao JC, Rudloff I, Ngo D, Lo CY, Soares da Costa TP, Perugini MA, Conroy PJ, Whisstock JC & Nold MF (2017) Homodimerization attenuates the anti-inflammatory activity of interleukin-37, Sci Immunol., 2(8): eaaj1548.

McCaffrey K, Boo I, Owczarek CM, Hardy MP, Perugini MA, Fabri L, Scotney P, Poumbourios P and Drummer HE (2016) An optimized hepatitis C virus E2 glycoprotein core adopts a functional homodimer that efficiently blocks virus entry, J Virol., 91(5): e01668-16.

Shahmiri M, Enciso M, Adda CG, Smith BJ, Perugini MA and Mechler A (2016) Membrane core-specific antimicrobial action of cathelicidin LL-37 peptide switches between pore and nanofibre formation, Sci Rep., 6: 38134.

Christensen JB, Soares da Costa TP, Faou P, Pearce FG, Panjikar S and Perugini MA (2016) Structure and function of cyanobacterial DHDPS and DHDPR, Sci Rep., 6: 37111.

Soares da Costa TP, Desbois S, Dogovski C, Gorman MA, Ketaren NE, Paxman JJ, Siddiqui T, Zammit LM, Abbott BM, Robins-Browne RM, Parker MW, Jameson GB, Hall NE, Panjikar S and Perugini MA (2016) Structural determinants defining the allosteric inhibition of an essential antibiotic target, Structure, 24(8): 1282-91.

Lee EF, Perugini MA, Pettikiriarachchi A, Evangelista M, Keizer D, Yao S and Fairlie WD (2016) The Beclin 1 N-terminal domain is intrinsically disordered, Autophagy, 12(3): 460-71.

Griffiths K, Dolezal O, Cao B, Nilsson SK, See HB, Pfleger KD, Roche M, Gorry PR, Pow A, Viduka K, Lim K, Lu BG, Chang DH, Murray-Rust TA, Kvansakul M, Perugini MA, Dogovski C, Doerflinger M, Zhang Y, Parisi K, Casey JL, Nuttall SD and Foley M (2016) i-bodies: human single domain antibodies that antagonize chemokine receptor CXCR4, J Biol Chem., pii: jbc.M116.721050.

Fraser NJ, Liu JW, Mabbitt PD, Correy G, Coppin CW, Lethier M, Perugini MA, Murphy JM, Oakeshott JG, Weik M and Jackson C (2016) Evolution of protein quaternary structure in response to selective pressure for increased thermostability, J Mol Biol., 428(11): 2359-71.

Gordon SE, Weber DK, Downton MT, Wagner J and Perugini MA (2016) Dynamic modelling reveals `hotspots' on the pathway to enzyme-substrate complex formation, PLoS Comp Biol., 12(3): e1004811.

Peverelli MG, Soares da Costa TP, Kirby N and Perugini MA (2016) Dimerization of bacterial diaminopimelate decarboxylase is essential for catalysis, J Biol Chem., 291(18): 9785-95.

Gordon SE and Perugini MA (2016) Protein-ligand interactions, in Uchiyama S, Arisaki F, Stafford WF and Laue TM eds., Analytical Ultracentrifugation: Instrumentation, Software, and Application, Springer, pp.329-53.

Nelson TG, Ramsay GD and Perugini MA (2016) Fluorescence-detection system, in Uchiyama S, Arisaki F, Stafford WF and Laue TM eds., Analytical Ultracentrifugation: Instrumentation, Software, and Application, Springer, pp.39-61.

Soares da Costa TP, Christensen JB, Desbois S, Gordon SE, Gupta R, Hogan CJ, Nelson TG, Downton MT, Ghardi CHTK, Abbott BM, Wagner J, Panjikar S and Perugini MA (2015) Quaternary structure analyses of an essential oligomeric enzyme, in Cole JL, ed., Analytical Ultracentrifugation: Methods in Enzymology, 562: 205-23.

Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Cölfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Díez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, Fairman R, Finn RM, Fischle W, de la Torre JG, Gor J, Gustafsson H, Hall D, Harding SE, Cifre JG, Herr AB, Howell EE, Isaac RS, Jao SC, Jose D, Kim SJ, Kokona B, Kornblatt JA, Kosek D, Krayukhina E, Krzizike D, Kusznir EA, Kwon H, Larson A, Laue TM, Le Roy A, Leech AP, Lilie H, Luger K, Luque-Ortega JR, Ma J, May CA, Maynard EL, Modrak-Wojcik A, Mok YF, Mücke N, Nagel-Steger L, Narlikar GJ, Noda M, Nourse A, Obsil T, Park CK, Park JK, Pawelek PD, Perdue EE, Perkins SJ, Perugini MA, Peterson CL, Peverelli MG, Piszczek G, Prag G, Prevelige PE, Raynal BD, Rezabkova L, Richter K, Ringel AE, Rosenberg R, Rowe AJ, Rufer AC, Scott DJ, Seravalli JG, Solovyova AS, Song R, Staunton D, Stoddard C, Stott K, Strauss HM, Streicher WW, Sumida JP, Swygert SG, Szczepanowski RH, Tessmer I, Toth RT 4th, Tripathy A, Uchiyama S, Uebel SF, Unzai S, Gruber AV, von Hippel PH, Wandrey C, Wang SH, Weitzel SE, Wielgus-Kutrowska B, Wolberger C, Wolff M, Wright E, Wu YS, Wubben JM and Schuck P (2015) A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation, PLoS One, 10(5): e0126420.

Peverelli MG and Perugini MA (2015) An optimized coupled assay for quantifying diaminopimelate decarboxylase activity, Biochimie., 115: 78-85.

Swarbrick CM, Perugini MA, Cowieson N and Forwood JK (2015) Structural and functional characterization of TesB from Yersinia pestis reveals a unique octameric arrangement of hotdog domains, Acta Crystallogr D Biol Crystallogr., 71(Pt 4): 986-95.

Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J and Vivian JP (2015) The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4, J Biol Chem., 290(16): 10460-71.

Lin CS, Uboldi AD, Marapana D, Czabotar PE, Epp C, Bujard H, Taylor NL, Perugini MA, Hodder AN and Cowman AF (2014) The merozoite surface protein 1 complex is a platform for binding to human erythrocytes by Plasmodium falciparum, J Biol Chem., 289(37): 25655-69.

Atkinson SC, Hor L, Dogovski C, Dobson RC and Perugini MA (2014) Identification of the bona fide DHDPS from a common plant pathogen, Proteins, 82(9): 1869-83.

Dogovski C, Gorman MA, Ketaren NE, Praszkier J, Zammit LM, Mertens HD, Bryant G, Yang J, Griffin MD, Pearce FG, Gerrard JA, Jameson GB, Parker MW, Robins-Browne RM and Perugini MA (2013) From knock-out phenotype to three-dimensional structure of a promising antibiotic target from Streptococcus pneumoniae, PLoS One, 8(12): e83419.

Heras B, Totsika M, Peters KM, Paxman JJ, Gee CL, Jarrott RJ, Perugini MA, Whitten AE and Schembri MA (2014) The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping, Proc Natl Acad Sci USA, 111(1): 457-62.

Soares da Costa TP, Yap MY, Perugini MA, Wallace JC, Abell AD, Wilce MC, Polyak SW and Booker GW (2014) Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus, Mol Microbiol., 91(1): 110-20.

Siddiqui T, Paxman JJ, Dogovski C, Panjikar S and Perugini MA (2013) Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogen Legionella pneumophila, Acta Crystallogr Sect F Struct Biol Cryst Commun., 69(Pt 10): 1177-81.

Traore DA, Brennan AJ, Law RH, Dogovski C, Perugini MA, Lukoyanova N, Leung EW, Norton RS, Lopez JA, Browne KA, Yagita H, Lloyd GJ, Ciccone A, Verschoor S, Trapani JA, Whisstock JC and Voskoboinik I (2013) Defining the interaction of perforin with calcium and the phospholipid membrane, Biochem J., 456(3): 323-35.

Yang J, Hocking DM, Cheng C, Dogovski C, Perugini MA, Holien JK, Parker MW, Hartland EL, Tauschek M and Robins-Browne RM (2013) Disarming bacterial virulence through chemical inhibition of the DNA binding domain of an AraC-like transcriptional activator protein, J Biol Chem., 288(43): 31115-26.

Hor L, Peverelli MG, Perugini MA and Hutton CA (2013) A new robust kinetic assay for DAP epimerase activity, Biochimie, 95(10): 1949-53.

Berry R, Ng N, Saunders PM, Vivian JP, Lin J, Deuss FA, Corbett AJ, Forbes CA, Widjaja JM, Sullivan LC, McAlister AD, Perugini MA, Call MJ, Scalzo AA, Degli-Esposti MA, Coudert JD, Beddoe T, Brooks AG and Rossjohn J (2013) Targeting of a natural killer cell receptor family by a viral immunoevasin, Nat Immunol., 14(7): 699-705.

Patel KK, Poon IK, Talbo GH, Perugini MA, Taylor NL, Ralph TJ, Hoogenraad NJ and Hulett MD (2013) New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties, IUBMB Life, 65(6): 550-63.

Hor L, Dobson RC, Downton MT, Wagner J, Hutton CA and Perugini MA (2013) Dimerization of bacterial diaminopimelate epimerase is essential for catalysis, J Biol Chem., 288(13): 9238-48.

Atkinson SC, Dogovski C, Downton MT, Czabotar PE, Dobson RC, Gerrard JA, Wagner J and Perugini MA (2013) Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition, Plant Mol Biol., 81(4-5): 431-46.