CXCR4 Binding Molecules: WO 2016/109872 A1

Ama-1 epitopes, antibodies, compositions, and methods of making and using the same: WO 2015/070207 A3


Griffiths K, Habiel DM, Jaffar J, Binder U, Darby WG, Hosking CG, Skerra A, Westall GP, Hogaboam CM and Foley M (2018) Anti-fibrotic Effects of CXCR4-Targeting i-body AD-114 in Preclinical Models of Pulmonary Fibrosis, Sci Rep., 8(1): 3212

Griffiths K, Dolezal O, Cao B, Nilsson SK, See HB, Pfleger KD, Roche M, Gorry PR, Pow A, Viduka K, Lim K, Lu BG, Chang DH, Murray-Rust TA, Kvansakul M, Perugini MA, Dogovski C, Doerflinger M, Zhang Y, Parisi K, Casey JL, Nuttall SD and Foley M (2016) i-bodies: human single domain antibodies that antagonize chemokine receptor CXCR4, J Biol Chem., 291(24): 12641-57.

Johnston A, Murphy KT, Jenkinson L, Laine D, Emmrich K, Faou P, Weston R, Jayatilleke KM, Schloegel J, Talbo G, Casey J, Levina V, Wong L, Dillon H, Sahay T, Hoogenraad J, Anderton H, Hall C, Schneider P, Tanzer M, Foley M, Scott A, Gregorevic P, Liu SY, Burkley LC, Lynch GS, Silke J and Hoogenraad N (2015) Targeting of Fn14 prevents cancer-induced cachexia and prolongs survival, Cell, 162(6): 1365-78.

Ge X, MacRaild CA, Devine S, Debono CO, Wang G, Scammells PJ, Scanlon MJ, Anders RF, Foley M and Norton RS (2014) Ligand-induced conformational change of Plasmodium falciparum AMA1 detected using (19)F NMR, J Med Chem., 57(15): 6419-27.

Harris KS, Adda CG, Khore M, Drew DR, Valentini-Gatt A,  Fowkes FJI, Beeson JG, Dutta S, Anders RF and Foley M (2014) Use of immunodampening to overcome diversity in the malarial vaccine candidate apical membrane antigen 1, Infect Immun., 82(11): 4707-17.

Griffiths K, Dolezal O, Parisi K, Angerosa J, Dogovski C, Barraclough M, Sanalla A, Casey JL, González I, Perugini MA, Nuttall S and Foley M (2013) Shark Variable New Antigen Receptor (VNAR) single domain antibody fragments: stability and diagnostic applications, Antibodies, 2(1): 66-81.

Dutta S, Dlugosz LS, Drew DR, Ge X, Ababacar D, Rovira YI, Moch JK, Shi M, Long CA, Foley M, Beeson JG, Anders RF, Miura K, Haynes JD and Batchelor AH (2013) Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1, PLoS Pathog., 9(12): e1003840.

Adda CG, Macraild CA, Reiling L, Wycherley K, Boyle MJ, Kienzle V, Masendycz P, Foley M, Beeson JG, Norton RS and Anders RF (2012) Antigenic characterisation of an intrinsically unstructured protein: Plasmodium falciparum merozoite surface protein 2, Infect Immun., 80(12): 4177-85.

Drew DR, Hodder AN, Wilson DW, Foley M, Mueller I, Siba PM, Dent AE, Cowman AF and Beeson JG (2012) Defining the antigenic diversity of Plasmodium falciparum apical membrane antigen 1 and the requirements for a multi-allele vaccine against malaria, PLoS One, 12: e51023.