For a complete list of publications see:

Ying L, Yan F, Meng Q, Yu L, Yuan X, Gantier MP, Williams BRG, Chan DW, Shi L, Tu Y, Ni P, Wang X, Chen W, Zang X, Xu D and Hu Y (2018) PD-L1 expression is a prognostic factor in subgroups of gastric cancer patients stratified according to their levels of CD8 and Foxp3 immune markers, OncoImmunology, 7(6): e1433520.

Lv Y-P, Teng Y-S, Mao F-Y, Peng L-S, Zhang J-Y, Cheng P, Liu Y-G, Kong H, Wang T-T, Wu X-L, Hao C-J, Chen W, Yang S-M, Zhao Y-L, Han B, Ma Q, Zou Q-M and Zhuang Y (2018) Helicobacter pylori-induced IL-33 modulates mast cell responses, benefits bacterial growth, and contributes to gastritis, Cell Death and Disease, 9.

Zanker D, Pang K, Oveissi S, Lu C, Faou P, Nowell C, Mbogo GW, Carotta S, Quillici C, Karupiah G, Hibbs ML, Nutt SL, Neeson P, Puthalakath H and Chen W (2018) LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins, Immunology and Cell Biology, 96: 981-993.

Mao F-Y, Zhao Y-L, Lv Y-P, Teng Y-S, Kong H, Liu Y-G, Wu X-L, Hao C-J, Chen W, Duan MB, Han B, Ma Q, Wang T-T, Peng L-S, Zhang J-Y, Cheng P, Su C-Y, Fu X-L, Zou Q-M, Guo G, Guo X-L and Zhuang Y (2018) CD45+CD33lowCD11bdim myeloid derived suppressor cell suppress CD8+ T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer, Cell Death & Diseases, 9(7): 763.

Han B, Mao F-Y, Zhao Y-L, Lv Y-P, Teng Y-S, Duan M, Chen W, Cheng P, Wang T-T, Liang Z-Y, Zhang J-Y, Liu Y-G, Guo G, Zou Q-M, Zhuang Y and Peng L-S (2018) Altered NKp30, NKp46, NKG2D and DNAM-1 expression on circulating NK cells is associated with tumor progression in human gastric cancer, J Immunol Res, 6248590.

Lv YP, Peng LS, Wang QH, Chen N, Teng YS, Wang TT, Mao FY, Zhang JY, Cheng P, Liu YG, Kong H, Wu XL, Hao CJ, Chen W, Zhu J, Han B, Ma Q, Li K, Zou Q and Zhuang Y (2018) Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression, Cell Death & Diseases, 9(10): 1034.

Zhang M, Du T, Long F, Yang X, Sun Y, Duan M, Zhang G, Liu Y, Zhou EM, Chen W* and Chen J* (2018) Platycodin D Suppresses Type 2 Porcine Reproductive and Respiratory Syndrome Virus In Primary and Established Cell Lines, Viruses, 10: 657. *authors contributed equally

Grant EJ, Josephs Y, Loh L, Clemens EB, Sant S, Bharadwaj M, Chen W, Rossjohn J, Gras S and Kedzierska K (2018) Broad CD8+ T cell receptor cross-recognition of distinct influenza A strains in humans, Nature Communications, 9: 5427.

Li L, Wei W, Li Z, Chen H, Li Y, Jiang W, Chen W, Kong G and Yang JLi Z(2018) Spleen promotes the secretion of CCL2 and supports a M1 dominant phenotype in hepatic macrophages during liver fibrosis, Cellular Physiology and Biochemistry, 51(2): 557-574.

Liu Y-G*, Teng Y-S*, Cheng P, Kong J, Lv Y-P, Mao F-Y, Wu X-L, Hao C-J, Chen W, Yang S-M, Zhang J-Y, Peng L-S, Wang T-T, Han B, Ma W, Rui Z, Zou Q-M and Zhuang Y (2018) Abrogation of Cathepsin C by Helicobacter pylori impairs neutrophil activation to promote gastric infection, FASEB J., doi: 10.1096/fj.201802016RR.

Di Carluccio AR, Triffon CF and Chen W (2018) Perpetual complexity: predicting human CD8+ T cell responses to pathogenic peptides, Immunology & cell biology, 94(4): 358-369.

Atkin-Smith GK*, Duan M*, Chen W and Poon IKH* (2018) The induction and consequences of influenza A virus-induced cell death, Cell Death & Disease, 9(10): 1002. *Co-corresponding authors

Chan KF, Gully BS, Gras S, Beringer DX, Kjer-Nielsen L, Cebon J, McCluskey J, Chen W* and Rossjohn J* (2018) Divergent T cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide, Nature Communications, 9(1): 1026.

Flavel M, Mechler A, Shahmiri M, Mathews E, Franks AE, Chen W, Zanker D, Tegene S, Doneski C and Jois M (2018) Growth of Caenorhabditis elegans in Defined Media Is Dependent on Presence of Particulate Matter, G3, 8(2): 567-575.

Zhang J-Y*, Lv Y-P*, Zhao Y-L, Cheng P, Chen W, Duan M, Teng Y-S, Wang T-T, Peng L-S, Mao F-Y, Liu Y-G, Fu X-L, Yu P-W, Luo P, Zhang W-J, Zou Q-M and Zhuang Y (2018) Modulation of CD8+ Memory Stem T Cell Activity and Glycogen Synthase Kinase 3β Inhibition Enhances Anti-Tumoral Immunity in Gastric Cancer, OncoImmunology, 7(4): e1412900.

Zhang M*, Wu Q*, Chen Y, Duan M, Tian G, Deng X, Sun Y, Zhang G*, Chen W* and Chen J* (2018) Inhibition of proanthocyanidin A2 on porcine reproductive and respiratory syndrome virus replication in vitro, Plos One, 13(2): e0193309.

Mao F, Kong H, Zhao Y, Chen W, Zhang J, Cheng P, Wang T, Lv Y, Teng Y, Fu X, Liu Y, You N, Luo P, Yu P, Zou Q, Guo G, Wu X, Hao C and Zhuang Y (2017) Increased tumor-infiltrating CD45RA-CCR7- regulatory T-cell subset with immunosuppressive properties foster gastric cancer progress, Cell Death & Diseases, 8(8): e1302.

Quinn KM, Kan W, Watson KA, Liddicoat BJ, McQuilten H, Denton AE, Swan NG, Li J, Chen W, Brown LE, Jackson DC, Reading PC, Kedizerska K, Kedzierski L, Turner SJ and La Gruta NL (2017) Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude, Plos One, 12(9): e0184732, doi:10.1371/journal.pone.0184732.

Li L, Duan M, Chen W, Jiang A, Li X, Yang J and Li Z (2017) The spleen in liver cirrhosis: revisiting an old enemy with novel targets, Journal of Translational Medicine, 15(1): 111, doi:10.1186/s12967-017-1214-8.

Wang T, Zhao Y, Peng L, Chen N, Chen W, Lv Y, Mao F, Zhang J, Cheng P, Li W, Teng Y, Fu X, Yu P, Guo G, Luo P, Zhang W, Yang L, Zhuang Y and Zou Q (2017) Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GMCSF-PD-L1 pathway, Gut, 66(11): 1900-1911, doi: 10.1136/gutjnl-2016-313075.

Davis ID, Quirk J, Morris L, Seddon L, Tai TY, Whitty G, Cavicchiolo T, Ebert L, Jackson H, Browning J, MacGregor D, Wittke F, Winkels G, Alex R, Miloradovic L, Maraskovsky E, Chen W, Cebon J (2017) A pilot study of peripheral blood BDCA-1 (CD1c) positive dendritic cells pulsed with NY-ESO-1 ISCOMATRIX® in patients with treated cancer and minimal residual disease at high risk of relapse, Immunotherapy, 9(3): 249-59.

Peng LS, Zhang JY, Teng YS, Zhao YL, Wang TT, Mao FY, Lv YP, Cheng P, Li WH, Chen N, Duan M, Chen W, Guo G, Zou QM and Zhuang Y (2017) Tumor-associated monocytes/macrophages impair NK-cell function via TGFbeta1 in human gastric cancer, Cancer Immunol Res., 5(3): 248-56.

Wei J, Zanker D, Di Carluccio AR, Smelkinson MG, Takeda K, Seedhom M, Dersh D, Yang N, Jadhav A, Chen W and Yewdell JW (2017) Varied role of ubiquitylation in generating MHC class I peptide ligands, J Immunol., 198(1): 3835-45.

Chen L, Anthony A, Oveissi S, Huang M, Zanker D, Xiao K, Wu C, Zou Q and Chen W (2017) Broad based CD4+ T cell responses to influenza A virus in a healthy individual that lacks typical immunodominance hierarchy, Front Immunol, 8: 375.

Duan M, Hibbs ML and Chen W (2017) The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis, Immunol Cell Biol., 95(3): 225-35.

Atkin-Smith GK, Paone S, Zanker DJ, Duan M, Phan TK, Chen W, Hulett MD and Poon IKH (2017) Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting, Sci Rep., 6(7): 39846.

Peng L, Mao F, Zhao Y, Wang T, Chen N, Zhang J, Cheng P, Li W, Lv Y, Teng L, Guo G, Luo P, Chen W, Zou Q* and Zhuang Y* (2016) Altered phenotypic and functional characteristics of CD3+CD56+ NKT-like cells in human gastric cancer, Oncotarget, 7(34): 55222-30.

Hu J*, Chen L*, Yang W, Li B, Sun H, Wei S, He Y, Zhao Z, Yang S,Zou Q, Chen W, Guo H and Wu C(2016) Systematic identification of immunodominant CD4+ T cell responses to HpaA in Helicobacter pylori infected individuals, Oncotarget, 7(34): 54380-91.

Vanderven HA, Ana-Sosa-Batiz F, Jegaskanda S, Rockman S, Laurie K, Barr I, Chen W, Wines B, Hogarth PM, Lambe T, Gilbert SC, Parsons MS and Kent SJ (2016) What lies beneath: antibody dependent natural killer cell activation by antibodies to internal influenza virus proteins, EBioMedicine, 8: 277-90.

Duan M, Hibbs ML and Chen W (2016) The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis, Immunol Cell Biol., doi:10.1038/icb.2016.97.

Chen J*, Duan M*, Zhao Y, Ling F, Xiao K, Li Q, Lu C, Qi W, Zeng Z, Liao M, Liu Y, Chen W (2015) Saikosaponin a inhibits influenza A virus replication and lung immunopathogenesis, Oncotarget, 6(40): 42541-56.

Chinnery HR, Naranjo Golborne C, Leong CM, Chen W, Forrester JV, McMenamin PG (2015) Retinal microglial activation following topical application of intracellular toll-like receptor ligands, Invest Ophthalmol Vis Sci, 56(12): 7377-86.

Chua B, Wong C, Mifsud E, Edenborough K, Tan A, Mercuri F, Rockman S, Chen W, Turner S, Doherty P, Kelso A, Brown L and Jackson D (2015) Inactivated influenza vaccine that provides rapid, innate-mediated protection and subsequent long-term adaptive immunity, mBio,6: e01024.

Duan M, Steinfort D, Smallwood D, Hew M, Chen W, Ernst M, Irving L, Anderson G and Hibbs M (2015) CD11b immunophenotyping identifies inflammatory profiles in mouse and human lungs, Mucosal Immunology, doi:10.1038/mi.2015.84.

Rautela J, Baschuk N, Slaney CY, Jayatilleke KM, Xiao K, Bidwell BN, Lucas EC, Hawkins ED, Lock P,  Wong CS, Chen W, Anderson RL, Hertzog PJ, Andrews DM, Möller A and Parker BS (2015) Loss of host type-I IFN signaling accelerates metastasis and impairs NK cell anti-tumor function in multiple models of breast cancer, Cancer Immunol Res., 3(11): 1207-17.

Wylie B, Seppanen E, Xiao K, Zemek R, Zanker D, Prato S, Foley B, Hart PH, Krozcek R, Chen W and  Waithman J (2015) Cross-presentation of cutaneous melanoma antigen by migratory XCR1 + CD103 − and XCR1 + CD103 + dendritic cells, Oncoimmunology, 4(8): e1019198.

Zanker D, Otto W, von Bergen M, Chen W and Janina Tomm (2015) Compartment resolved reference map from highly purified naïve, activated, effector, central memory and effector memory CD8+ cells, Proteomics, 15(11): 1808-12.

Zanker D, Quinn K, Waithman J, Lata R, Murphy R, La Gruta N and Chen W (2015) T cells recognizing a 11mer influenza peptide complexed to H-2Db show promiscuity for peptide length, Immunol Cell Biol., 93(5): 500-07.

Klein O, Davis ID, McArthur GA, Haydon A, Parente P, Dimopoulos P, Jackson H, Maraskovsky E, Hopkins W, Stan R, Chen W and Cebon J (2015) Low dose cyclophosphamide enhances antigen-specific CD4+ lymphocyte responses to NY-ESO-1/ISCOMATRIXTM vaccine in patients with advanced melanoma, Cancer Immunol Immunther., 64(4): 507-18.

Chinnery HR, Leong CM, Chen W, Forrester JV and McMenamin PG (2015) TLR9 and TLR7/8 activation induces formation of keratic precipitates and giant macrophages in the mouse cornea, J Leukoc Biol., 97(1): 103-10.

Verdon TJ, Mitchell RJ, Chen W, Xiao K and van Oorschot RA (2015) FACS separation of non-compromised forensically relevant biological mixtures, Forensic Sci Int Genet., 14: 194-200.

Greening DW, Xu R, Gopal SK, Simpson RJ and Chen W (2015) Exosomes and immunoregulation in cancer progression, Semin Cell Dev Biol., 40: 72-81.

Sheng J, Chen W and Zhu H (2015) Immune suppression function of Transforming Growth Factor-β (TGF-β) in human diseases, Growth Factors, 33(2): 92-101.

Zhuang Y, Liu XF, Cheng P, Shi Y, Li BS, Peng LS, Wang TT, Chen N, Li WH, Chen W, Pang KC, Liu T, Guo H, Yang SM, Zhou YY, Zuo XF, Yang HJ, Yang LY, Mao XH, Zhang YJ, Zeng H, Guo G, Tong WD, Tang B, Luo P, Zhang WJ and Zou QM (2014) A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis, Gut, 64(9): 1368-78.

Chen L, Zanker D, Xiao K, Wu C, Zou Q and Chen W (2014) Immunodominant CD4+ T-cell responses to influenza A virus in healthy individuals focus on matrix 1 and nucleoprotein, J Virol., 88(20): 11760-73.

Vella LJ, Pasam A, Dimopoulos N, Andrews M, Knights A, Puaux AL, Louahed J, Chen W, Woods K and Cebon J (2014) MEK inhibition, alone or in combination with BRAF inhibition, effects multiple functions of isolated normal human lymphocytes and dendritic cells, Cancer Res Immunol., 2(4): 351-60.

Peng LS, Zhou YY, Wang TT, Chen N, Cheng P, Li BS, Li, Guo H, Chen W, Zhang Y* and  Zou QM* (2014) Elevated Interleukin-32 expression is associated with Helicobacter pylori-related gastritis, Plos One, 9(3): e88270.

Tan BS, Anaka M, Deb S, Freyer C, Ebert LM, Chueh AC, Al-Obaidi S, Behren A, Jayachandran A, Cebon J, Chen W* and Mariadason JM* (2014) FOXP3 is infrequently expressed in human melanoma and its over-expression inhibits melanoma cell growth, Oncotarget, 5(1): 264-76.

Sarvestani S, Tate M, Moffat J, Jacobi A, Behlke M, Miller A, Beckham S, McCoy C, Chen W, Mintern J, O'Keeffe M, John M, Williams B and Gantier M (2014) Inosine-mediated modulation of RNA sensing by TLR7/8, J Virol., 88(2): 799-810.

Grant EJ, Chen L, Quiñones-Parra S, Pang K, Kedzierska K and Chen W (2014) T Cell immunity to influenza A viruses, Curr Rev Immunol., 34(1): 15-39.

Zanker D and Chen W (2014) Standard and immunoproteasomes show similar peptide degradation specificities, Eur J Immunol., 44(12): 3500-03.

Wei J, Waithman J, Xiao K, Oveissi S and Chen W (2013) Optimizing conditions required for enhanced cross-priming mediated by influenza infection of tumor cells, Immunol Cell Biol., 91(9): 576-82.

Zanker D, Waithman J, Yewdell J and Chen W (2013) Mixed immunoproteasomes function to increase viral peptide diversity and broaden anti-viral TD8+ responses, J Immunol., 191(1): 52-59.

Waithman J, Zanker J, Xiao K, Oveissi S, Wylie B, Ng R, Tögel L and Chen W (2013) Resident CD8+ and migratory CD103+ dendritic cells control CD8+ T cell immunity during acute influenza infection, Plos One, 8(6): e66136.

Komatsu N, Jackson HM, Chan KF, Oveissi S, Cebon J, Itoh K and Chen W (2013) Fine-mapping naturally accruing NY-ESO-1 antibody epitopes in melanoma patients' sera using short overlapping peptides and full-length recombinant protein, Mol Immunol., 54(3-4): 465-71.

Grant E*, Wu C*, Chan KF, Eckle S, Bharadwaj M, Zou QM, Kedzierska K and Chen W (2013) Nucleoprotein of influenza A virus is a major target of immunodominant CD8+ T cell responses, Immunol Cell Biol., 91(2): 184-94.

Chen L, Li B, Yang W, He J, Li N, Hu J, He Y, Yu S, Zhao Z, Luo P, Zhang J, Lu D, Li H, Guo H, Yang S, Guo G, Mao X, Chen W*, Wu C* and Zou Q* (2013) A dominant CD4+ T-cell response to Helicobacter pylori is associated with decreased risk of gastric diseases in Chinese, Gastroeterology, 144(3): 591-600.

Luciani F, Sanders MT, Oveissi S, Pang KC and Chen W (2013) Increasing viral dose causes a reversal in CD8+ T cell immunodominance during primary influenza infection due to differences in Ag presentation, T cell avidity and precursor numbers, J Immunol., 190(1): 36-47.

*Contributed equally to work.