A Method: WO 2017/054044 A1

Generation of Peptides: WO 2017/049362 A1

A Method of in vivo Treatment: WO 2016/191790 A1

A Method of Treatment: WO 2016/061619 A1

Agents and methods for treatment of pathogens: WO 2015/161346 A1

Agents and methods of treatment: WO 2015/161348 A1

Anti-pathogenic methods: WO 2014/078900 A1

Novel plant defensins and use in the treatment of proliferative diseases: WO 2013/056309 A1

Use of antifungal defensins: AU 2013/260696 A1

Defensin variants and methods of use: US 2012/0054911 A1

Novel antifungal proteins and methods of use: US 2012/0102595 A1

Modified plant defensins useful as anti-pathogenic agents: WO 2012/106759 A1

Treatment of proliferative diseases: WO 2011/160174 A1

Plant anti-pathogen systems: WO 2010/015024 A1

Anti fungal methods: WO 2009/094719 A1

Multi-gene expression vehicle: WO 2007/137329 A9

Nucleic acids encoding plant defensins and methods of use thereof: WO 2004/001012 A2

Insect chymotrypsin and inhibitors thereof: WO 2004/094630 A1

Defensin polynucleotides and methods of use: US 2003/0041438 A1

Plant-derived molecules and genetic sequences encoding same and uses therefor: WO 2002/063011 A1

Novel nucleic acid molecules: WO 2001/034829 A2



Dash TS, Shafee T, Harvey PJ, Zhang C, Peigneur S, Deuis JR, Vetter I, Tytgat J, Anderson M, Craik DJ, Durek T and Undheim EAB (2019) A centipede toxin family defines an ancient class of CSαβ defensins, Structure, 27(2): 315-326.e7.

Shafee T and Anderson MA (2018) A quantitative map of protein sequence space for the cis-defensin superfamily, Bioinf., doi: 10.1093/bioinformatics/bty697.

Jackson A, Gilding EK, Shafee T, Harris KS, Kaas Q, Poon S, Yap K, Jia H, Guarino R, Chan LY, Durek T, Anderson MA and Craik DJ (2018) Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases, Nat. Comm., 9: 2411.

Hayes B, Bleackley M, Anderson MA and van der Weerden N (2018) The plant defensin NaD1 enters the cytoplasm of Candida albicans via endocytosis, J Fungi, 4(1).

Parisi K, Shafee TMA, Quimbar P, van der Weerden NL, Bleackley MR and Anderson MA (2018) The evolution, function and mechanisms of action for plant defensins, Seminars in Cell and Developmental Biology, DOI: 10.1016/j.semcdb.2018.02.004.

Jӓrvå M, Lay FT, Phan TK, Humble C, Poon IKH, Bleackley MR, Anderson MA, Hulett MD and Kvansakul M (2018) X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex, Nat. Comm., 9(1): 1962.

McColl AI, Bleackley MR, Anderson MA and Lowe RGT (2018) Resistance to the Plant Defensin NaD1 Features Modifications to the Cell Wall and Osmo-Regulation Pathways of Yeast, Frontiers in Micro., 9: 1648.

Poon S, Harris KS, Jackson MA, McCorkelle OC, Gilding EK, Durek T, van der Weerden NL, Craik DJ and Anderson MA (2017) Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta, Journal of Experimental Botany, erx422.

Bleackley MR, Dawson CS, McKenna JA, Quimbar P, Hayes BME, van der Weerden NL and Anderson MA (2017) Synergistic Activity between Two Antifungal Proteins, the Plant Defensin NaD1 and the Bovine Pancreatic Trypsin Inhibitor, mSphere, 2(5): e00390-17.

Shafee TM, Lay FT, Phan TK, Anderson MA and Hulett MD (2017) Convergent evolution of defensin sequence, structure and function, Cell Mol Life Sci., 74(4): 663-82.

Payne J, Lee TH, Anderson M and Aguilar MI (2017) Examination of the Interaction between a Membrane Active Peptide and Artificial Bilayers by Dual Polarisation Interferometry, Bio-protocol, 7(1): e2087.

Shafee TM, Lay FT, Phan TK, Anderson MA and Hulett MD (2016) Convergent evolution of defensin sequence, structure and function, Cell Mol Life Sci., 74(4): 663-82.

Bleackley MR, Payne JA, Hayes BM, Durek T, Craik DJ, Shafee TM, Poon IK, Hulett MD, van der Weerden NL and Anderson MA (2016) Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variant, Antimicrob Agents Chemother., 60(10): 6302-12.

Daly NL, Gunasekera S, Clark RJ, Lin F, Wade JD, Anderson MA and Craik DJ (2106) The N‐terminal pro‐domain of the kalata B1 cyclotide precursor is intrinsically unstructured, Pep Sci., 106(6): 825-33.

Shafee TM, Lay FT, Hulett MD and Anderson MA (2016) The defensins consist of two independent, convergent protein superfamilies, Mol Biol Evol., 33(9): 2345-56.

Payne JA, Bleackley MR, Lee T-H, Shafee TM, Poon IKH, Hulett MD, Aguilar M-I, van der Weerden NL and Anderson MA (2016) The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate, Biochim Biophys Acta, 1858(6):1099-109.

Dracatos PM, Payne J, Di Pietro A, Anderson MA and Plummer KM (2016) Plant defensins NaD1 and NaD2 induce different stress response pathways in fungi, Int J Mol Sci., 17(9): 1473.

Shafee TM, Robinson AJ, van der Weerden N and Anderson MA (2016) Structural homology guided alignment of cysteine rich proteins, SpringerPlus, 5: 27.

Shafee T and Cooke I (2016) AlignStat: A web-tool and R package for statistical comparison of alternative multiple sequence alignments, BMC Bioinformatics, 17: 434.

Masukume G, Kipersztok L, Das D, Shafee T, Laurent M and Heilman J (2016) Medical journals and Wikipedia: a global health matter, Lancet Glob Health, 4(11): e791.

Strugnell J, Shafee T and Baeseman J (2016) Kudos for female Antarctic researchers, Nature, 148(536): doi:10.1038/536148b.

Shafee TMA, Robinson AJ, van der Weerden N and Anderson MA (2016) Structural homology guided alignment of cysteine rich proteins, Springerplus, 5 (27), doi: 10.1038/ncomms10199.

Lowe R, McCorkelle O, Bleackley M, Collins C, Faou P, Mathivanan S and Anderson MA (2015) Extracellular proteases of the cereal pathogen Fusarium graminearum, Front Plant Sci., 6: 962, doi: 10.3389/fpls.2015.00962.

Harris KS, Durek T, Kaas Q, Poth AG, Gilding EK, Conlan BF, Saska I, Daly NL, van der Weerden NL, Craik DJ and Anderson MA (2015) Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase, Nat Comm., doi: 10.1038/ncomms10199.

Shafee T, Harris K and Anderson M (2015) Biosynthesis of cyclotides, Adv Bot Res., 76: 227-69.

Baxter AA, Richter V, Lay FT, Poon IKH, Adda CG, Veneer PK, Phan TK, Bleackley MR, Anderson MA, Kvansakul M and Hulett MD (2015) The tomato defensin TPP3 binds phosphatidylinositol (4, 5)-bisphosphate via a conserved dimeric cationic grip conformation to mediate cell lysis, Mol Cell Biol., 35(11): 1964-78.

Samuel M, Bleackley M, Anderson M and Mathivanan S (2015) Extracellular vesicles including exosomes in cross kingdom regulation: a viewpoint from plant-fungal interactions, Front Plant Sci., 6: 766, doi: 10.3389/fpls.2015.00766.

Hayes BME, Anderson MA, Traven A, van der Weerden NL and Bleackley MR (2014) Activation of stress signalling pathways enhances tolerance of fungi to chemical fungicides and antifungal proteins, Cell Mol Life Sci., 71(14): 2651-66.

Bleackley MR, Hayes B, Parisi K, Saiyed T, Traven A, Potter ID, Weerden N and Anderson MA (2014) Bovine pancreatic trypsin inhibitor is a new antifungal peptide that inhibits cellular magnesium uptake, Mol Microbiol., 92(6): 1188-97.

Gaspar YM, McKenna JA, McGinness BS, Hinch J, Poon S, Connelly AA, Anderson MA and Heath RL (2014) Field resistance to Fusarium oxysporum and Verticillium dahliae in transgenic cotton expressing the plant defensin NaD1, J Exp Bot.,  65(6): 1541-50.

Lay FT, Poon S, McKenna JA, Connelly AA, Barbeta BL, McGinness BS, Fox JL, Daly NL, Craik DJ, Heath RL and Anderson MA (2014) The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions, BMC Plant Biol., doi: 10.1186/1471-2229-14-41.

Dracatos PM, van der Weerden NL, Carroll KT, Johnson ED, Plummer KM and Anderson MA (2013) Inhibition of cereal rust fungi by both class I and II defensins derived from the flowers of Nicotiana alata, Mol Plant Pathol., 15(1): 67-79.

Hayes BM, Bleackley MR, Wiltshire JL, Anderson MA, Traven A and van der Weerden NL (2013) Identification and mechanism of action of the plant defensin NaD1 as a new member of the antifungal drug arsenal against Candida albicans, Antimicrob Agents Chemother., 57(8): 3667-75.

Garvey M, Meehan S, Gras SL, Schirra HJ, Craik DJ, van der Weerden NL, Anderson MA, Gerrard JA and Carver JA (2013) A radish seed antifungal peptide with a high amyloid fibril-forming propensity, Biochim Biophys Acta., 1834(8): 1615-23.

Quimbar P, Malik U, Sommerhoff CP, Kaas Q, Chan LY, Huang YH, Grundhuber M, Dunse K, Craik DJ, Anderson MA and Daly NL (2013) High-affinity cyclic peptide matriptase inhibitors, J Biol Chem., 288(19): 13885-96.

van der Weerden NL, Bleackley MR and Anderson MA (2013) Properties and mechanisms of action of naturally occurring antifungal peptides, Cell Mol Life Sci., 70(19): 3545-70.