Staff profile

Qualifications

• BSc(Hons) Zoology, PhD La Trobe University

Teaching areas

• MED3MSB - Medical Science B (3rd year) - Neuromuscular disorders
• Heron Island Field Course (3rd year)

Professional involvement

• Member of Australian Physiological Society
• Member of the American Physiological Society
• Member of MyoNaK Society
• Grant assessor for NH&MRC
• Review research articles for American Journal of Clinical Nutrition, Journal of Applied Physiology, American  Journal of  Cell Physiology (Cell physiol), Acta Agri Scand A Animal Sci.

Research interests

• Primarily, my research focuses on how skeletal muscle cells normally function and how their function might be altered under diseased or fatigued states. My studies predominantly utilise single muscle cells (fibres) that have their surface membrane (sarcolemma) removed.

Recent publications and presentations

Publications

• Murphy RM, Dutka TL, Lamb GD. Hydroxyl radical and glutathione interactions alter calcium sensitivity and maximum force of the contractile apparatus in rat skeletal muscle fibres. J Physiol. 2008 Apr 15;586(8):2203-16.
• Dutka TL, Murphy RM, Stephenson DG & Lamb GD. Chloride Conductance in the Transverse Tubular System of Rat Skeletal Muscle Fibres: Importance in Excitation-Contraction Coupling and Fatigue. J Physiol. 2007
• Dutka TL & Lamb GD. Transverse tubular system depolarization reduces tetanic force in rat skeletal muscle fibers by impairing action potential repriming. Am J Physiol Cell Physiol. 2007, 292, C2112-2121.
• Dutka TL & Lamb GD. Preferential ATP usage by T-system Na+/K+-ATPase of mammalian skeletal muscle. Am J Physiol Cell Physiol.  2007, 293, C967-77.
• Verburg E, Dutka TL & Lamb GD. Long-lasting muscle fatigue: partial disruption of excitation-contraction coupling by elevated cytosolic Ca2+ concentration during contractions. Am J Physiol Cell Physiol. 2006 Apr;290(4):C1199-208.
• Dutka,T.L., Cole,L. and Lamb,G.D. (2005). Calcium-phosphate precipitation in the sarcoplasmic reticulum reduces action potential-mediated Ca2+ release in mammalian skeletal muscle. American Journal of Physiology, 289, C1502-1512
• Dutka,T.L. and Lamb,G.D. (2004). Effect of carnosine on excitation-contraction coupling in mechanically-skinned rat skeletal muscle. J Mus Res Cell Motil, 25, 203-213,
• Dutka,T.L. and Lamb,G.D. (2004). Effect of low cytoplasmic [ATP] on excitation-contraction coupling in fast-twitch muscle fibres of the rat. J Physiol. In Press.
• Posterino,G.S., Dutka,T.L. and Lamb,G. D. (2001). L(+)-lactate does not affect twitch and tetanic responses in mechanically skinned mammalian muscle fibres. Pflugers Arch. 442, 197-203
• Dutka,T.L. and Lamb,G.D. (2000). Effect of lactate on depolarization-induced Ca(2+) release in mechanically skinned skeletal muscle fibers. Am J Physiol Cell Physiol. 278, C517-525

Conference presentations

• Exercise, Metabolism & Muscle Conference, Melbourne (2009). Invited Speaker
• Biennial Internatonal MyoNaK Conference, palm Cove (2009). Speaker
• AuPS, Conference, Melbourne (2008) Oral
• AuPS/ASB Conference, Newcastle (2007) Poster
• ComBio2006, Brisbane (2006) Poster
• MEG, Melbourne VUT (2006) Speaker
• AuPS/ASB Conference, Canberra (2005). Invited Speaker
• NHMRC International Congress in Sydney (2004). Speaker
• APPS, University of Sydney, Sydney (2003). Speaker
• NHMRC International Congress in Melbourne (2002). Poster (CEPP best poster award)
• IUPS 34th International congress, Christchurch (2001). Poster
• IUPS satellite conference, Heron Island, QLD (2001). Poster
• APPS, RMIT Melbourne (2000). Speaker
• Curtin conference, Canberra (2000). Speaker